Results 151 to 160 of about 922,646 (221)

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

open access: yesAnimal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen   +2 more
wiley   +1 more source

Design, Synthesis and Biological Activity Evaluation of β-Carboline Derivatives Containing Nitrogen Heterocycles. [PDF]

open access: yesMolecules
Wu G   +10 more
europepmc   +1 more source

Accelerating green heterocyclic synthesis: Convergence of AI, automation, and sustainable chemistry

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Green heterocyclic synthesis and data‐driven tools such as AI, high‐throughput experimentation, continuous flow, and self‐driving laboratories have developed largely in parallel. This review connects them and asks how green metrics such as E‐factor and PMI might serve as explicit optimization targets rather than post‐hoc measures, toward sustainable ...
Noor Aisyah Ahmad Shah   +8 more
wiley   +1 more source

Multicomponent reactions for DNA‐encoded library construction: Scaffold diversity and reaction engineering strategies

open access: yesBulletin of the Korean Chemical Society, EarlyView.
Abstract DNA‐encoded libraries (DELs) enable large‐scale screening for hit identification, but accessing sp3‐rich, three‐dimensional chemotypes beyond flat, aromatic scaffolds remains challenging. Multicomponent reactions (MCRs) assemble such complexity from simple building blocks in a single step, and reaction‐engineering strategies have extended on ...
Jimin Moon   +3 more
wiley   +1 more source

Synthesis and Energetic Characterization of Borane-Amines on High-Nitrogen Heterocycles. [PDF]

open access: yesACS Omega
Lin R   +7 more
europepmc   +1 more source

Combined Enzyme- and Transition Metal-Catalyzed Strategy for the Enantioselective Syntheses of Nitrogen Heterocycles: (-)-Coniine, DAB-1, and Nectrisine. [PDF]

open access: yesACS Omega, 2020
Deardorff DR   +8 more
europepmc   +1 more source

Ternary Crosslinking Builds Nanosheet Hard Carbon and Interfacial Polarization Regulates Na⁺ Kinetics in Hard Carbon Anodes

open access: yesCarbon Energy, EarlyView.
Nanosheet Hard Carbon for Fast Na+ Storage ABSTRACT Hard‐carbon anodes for sodium‐ion batteries are often constrained by low initial Coulombic efficiency, severe interfacial polarization, and sluggish Na⁺ kinetics, especially when porosity engineering amplifies electrolyte consumption.
Dongke Cai   +5 more
wiley   +1 more source

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