Deuterium-labeled compounds play a pivotal role in physical organic chemistry, life sciences, and materials science. This has resulted in a surge of interest in deuterium-labeled active pharmaceutical ingredients in recent years.
Gellért, Sipos +5 more
core +1 more source
Rhodium-Catalyzed C-H Alkenylation/Electrocyclization Cascade Provides Dihydropyridines That Serve as Versatile Intermediates to Diverse Nitrogen Heterocycles. [PDF]
Dongbang S, Confair DN, Ellman JA.
europepmc +1 more source
Energetic and Geometric Characteristics of the Substituents: Part 2: The Case of NO2, Cl, and NH2 Groups in Their Mono-Substituted Derivatives of Simple Nitrogen Heterocycles. [PDF]
Wieczorkiewicz PA +2 more
europepmc +1 more source
Late‐Stage Functionalization of Peptides on the Solid Phase
Peptide modifications are essential to control pharmacodynamic and pharmacokinetic properties of peptide drugs. Consequently, strategies that allow for efficient and rapid incorporation of non‐canonical modifications into peptides in parallel formats are highly sought after.
Marius Werner +2 more
wiley +1 more source
Prescribed drugs containing nitrogen heterocycles: an overview. [PDF]
Heravi MM, Zadsirjan V.
europepmc +1 more source
Microwave assisted synthesis of five membered nitrogen heterocycles. [PDF]
Meera G +3 more
europepmc +1 more source
An unusual formal migrative cycloaddition of aurone-derived azadienes: synthesis of benzofuran-fused nitrogen heterocycles. [PDF]
Feng Q, Wu A, Zhang X, Song L, Sun J.
europepmc +1 more source
Biological and Teratogenic Evaluations of Nitrogen Heterocycles for Anticancer Therapy. [PDF]
Dos Santos JC +12 more
europepmc +1 more source
Double Ionization of Polycyclic Aromatic Nitrogen Heterocycles: Simulations on Phenanthridine. [PDF]
Basilio JHC +4 more
europepmc +1 more source
Multicomponent Syntheses of glycoside-decorated N-heterocyclic pharmacophores
We report in this communication on the synthesis of carbohydrate decorated N-heterocycles, namely dihydropyrimidin-2-ones, dihydropyridines, and azetidin-2-ones, via multicomponent Biginelli, Hantzsch, and Staudinger reactions ...
MASSI, Alessandro, DONDONI, Alessandro
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