Results 211 to 220 of about 2,262,605 (283)
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Nitrogen mustard prevents transport of Fra-1 into the nucleus to promote c-Fos- and FosB-dependent IL-8 induction in injured mouse epidermis.

Toxicology Letters, 2020
Transcription factor activator protein (AP)-1 can be activated in nitrogen-mustard-injured mouse skin, and is thought to participate in the inflammatory response.
Feng Ye   +7 more
semanticscholar   +1 more source

Synthesis and antitumor activity of formononetin nitrogen mustard derivatives

European Journal of Medicinal Chemistry, 2012
Xin Chen, Jie Ren, Hua-Jin Xu
exaly   +2 more sources

Comparative genotoxicity of nitrogen mustard and nor-nitrogen mustard

Carcinogenesis, 1984
Nitrogen mustard and nor-nitrogen mustard were investigated in Salmonella typhimurium and human lymphocytes for genotoxicity. Point mutations were assessed using the plate test, the conventional spot test and a method in which the substances were not in direct contact with the microorganisms. Both compounds were active, but nor-nitrogen mustard was far
B, Hartley-Asp, F, Hyldig-Nielsen
openaire   +2 more sources

Redox-Driven Disassembly of Polymer–Chlorambucil Polyprodrug: Delivery of Anticancer Nitrogen Mustard and DNA Alkylation

ACS Applied Polymer Materials, 2019
Utilization of nitrogen mustards as anticancer drugs opened the way for precise cancer chemotherapy owing to their ability to cross-link deoxyribonucleic acid (DNA).
B. Saha   +4 more
semanticscholar   +1 more source

Efficient nitrogen removal in a modified sequencing batch biofilm reactor treating hypersaline mustard tuber wastewater: The potential multiple pathways and key microorganisms.

Water Research, 2020
This study first compared the efficiencies and mechanisms of the nitrogen removal in an aerobic sequencing batch biofilm reactor (SBBR) treating mustard tuber wastewater from high salt (30 gNaCl L-1) to ultra-high salt (70 gNaCl L-1).
Jia-Le Wang   +5 more
semanticscholar   +1 more source

A Nitrogen Mustard Induces Formation of DNA-Histone Cross-Links in Nucleosome Core Particles.

Chemical Research in Toxicology, 2019
Nitrogen mustards have long been used in cancer chemotherapy, and their cytotoxicity has traditionally been attributed to the formation of DNA interstrand cross-links and DNA monoalkylation.
Mengdi Shang   +2 more
semanticscholar   +1 more source

Nitrogen mustard gas molecules and α-arsenene nanosheet interaction studies - A DFT insight.

Journal of Molecular Graphics and Modelling, 2019
Bis(2-chloroethyl)ethylamine (HN-1) and Bis(2-chloroethyl)methylamine (HN-2) are two classifications under the blistering agents, which are taken as target nitrogen mustard gas in the current research. α-arsenene nanosheets in its puckered configuration,
R. Bhuvaneswari   +2 more
semanticscholar   +1 more source

Synergistic Cancer Therapy: An NIR-Activated Methylene Blue-Nitrogen Mustard Prodrug for Combined Chemotherapy and Photodynamic Therapy.

Journal of Medicinal Chemistry
Nitrogen mustard, a widely used chemotherapeutic agent for more than 70 years, exhibits significant efficacy. However, its clinical applications are severely limited by poor tumor selectivity and severe side effects on normal tissues.
Tianyu Zhu   +6 more
semanticscholar   +1 more source

High-efficiency salt, sulfate and nitrogen removal and microbial community in biocathode microbial desalination cell for mustard tuber wastewater treatment.

Bioresource Technology, 2019
Considering there is no study involving simultaneous salt, sulfate and nitrogen removal from high-salinity mustard tuber wastewater (MTWW), biocathode microbial desalination cell (BMDC) was first constructed and used to treat MTWW.
Lin-Fang Zhang, Guo-Kai Fu, Zhi Zhang
semanticscholar   +1 more source

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