Results 221 to 230 of about 23,150 (274)
Comparative genotoxicity of nitrogen mustard and nor-nitrogen mustard [PDF]
Carcinogenesis, 1984 Nitrogen mustard and nor-nitrogen mustard were investigated in Salmonella typhimurium and human lymphocytes for genotoxicity. Point mutations were assessed using the plate test, the conventional spot test and a method in which the substances were not in direct contact with the microorganisms. Both compounds were active, but nor-nitrogen mustard was far
Beryl Hartley-Asp, F. Hyldig-Nielsen
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Inactivation of Complement by Nitrogen Mustard [PDF]
Nature, 1948 THE recent clinical use of the nitrogen mustards for the treatment of Hodgkin‘s and other neoplastic diseases1 has focused attention on these compounds and more particularly on their biological action. The intensive study of these vesicants made during the War2, when they were regarded as potential chemical warfare agents, has been continued in the ...
Arthur Wormall, W. M. Watkins
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EXPERIENCES WITH NITROGEN MUSTARD THERAPY
Journal of the American Medical Association, 1949Until recently, the palliative treatment of lymphoblastoma and other neoplastic diseases has depended almost entirely on the use of irradiation by roentgen rays or radium. With the recent introduction of the nitrogen mustards as potential therapeutic agents in this field, a concentrated effort has been made by various groups of investigators1to ...
C. C. Shullenberger +2 more
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TREATMENT OF PSORIASIS WITH TOPICAL NITROGEN MUSTARD [PDF]
International Journal of Dermatology, 1979 With the advent of various new methods of treating psoriasis, it is necessary to remind physicians to consider an agent that is easy to administer, locally effective, relatively inexpensive, not time-consuming and without systemic toxic effects. Nineteen patients were treated with topical nitrogen mustard between 1972 and 1976, and only five developed ...
Roland S. Medansky, Raymond M. Handler
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Journal of Pharmaceutical Sciences, 1967
As potential anticancer agents, three new 3-thenyl nitrogen mustards have been prepared from the corresponding diethanolamine derivatives. The NMR data for these compounds are reported.
W. Lewis Nobles, Charles M. Darling
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As potential anticancer agents, three new 3-thenyl nitrogen mustards have been prepared from the corresponding diethanolamine derivatives. The NMR data for these compounds are reported.
W. Lewis Nobles, Charles M. Darling
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NITROGEN MUSTARD IN THE TREATMENT OF MYCOSIS FUNGOIDES [PDF]
Journal of the American Medical Association, 1947 Nitrogen mustard has been used in the treatment of a case of mycosis fungoides. REPORT OF CASE C. D., a man aged 79, had mycosis fungoides for the past four years. Lesions evolved through the premycotic and mycotic stages in the usual fashion. Previously roentgen therapy had controlled the infiltrations and tumors nicely. On Feb.
A. R. Woodburne +2 more
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Effect of nitrogen mustard of hyaluronate
Biochemical Pharmacology, 1969Abstract The effect in vitro of nitrogen mustard (HN2) treatment on physical parameters of partially purified hyaluronate from human umbilical cords and of synovial fluid from patients with rheumatoid arthritis was studied. Intrinsic viscosities, gel filtration elution patterns (Sepharose 2B) and acrylamide gel disk electrophoresis runs on HN2 ...
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JAMA: The Journal of the American Medical Association, 1984
The beginning of the era of cytotoxic chemotherapy was documented in this signal publication. The title is a concise yet accurate description of the contents of the publication. The trivial name assigned to this chemical — nitrogen mustard —persists today, and the association of the chemical with the word therapy was virtually clairvoyant. The authors
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The beginning of the era of cytotoxic chemotherapy was documented in this signal publication. The title is a concise yet accurate description of the contents of the publication. The trivial name assigned to this chemical — nitrogen mustard —persists today, and the association of the chemical with the word therapy was virtually clairvoyant. The authors
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NITROGEN MUSTARD IN TREATMENT OF RHEUMATOID ARTHRITIS
Journal of the American Medical Association, 1953The value of corticotropin (ACTH) and cortisone in rheumatoid arthritis and allied diseases has been well established. The pituitary-adrenal axis relationship has been described by Selye 1 and others, and this has been the stimulus for various types of clinical application.
Edward S. Cooper +2 more
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