3D- and 2D-QSAR models’ study and molecular docking of novel nitrogen-mustard compounds for osteosarcoma [PDF]
Frontiers in Molecular Biosciences, 2023 Background: The dipeptide-alkylated nitrogen-mustard compound is a new kind of nitrogen-mustard derivative with a strong anti-tumor activity, which can be used as a potential anti-osteosarcoma chemotherapy drug.Objective: 2D- and 3D-QSAR (structure ...
Wenkun Zhuo +4 more
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Covalent Protein Adduction of Nitrogen Mustards and Related Compounds
, 2017 Chemical warfare agents continue to pose a global threat despite the efforts of the international community to prohibit their use in warfare. For this reason, improvement in the detection of these compounds remains of forensic interest. Protein adducts formed by the covalent modification of an electrophilic xenobiotic and a nucleophilic amino acid may ...
Vanessa R. Thompson
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Studies on the protective action of cysteamine and related compounds against nitrogen mustard (HN2) injected into mice [PDF]
Acta Radiologica, 1958 Investigations into the protective action of cyeteamine against nitrogen mustard (HN2) are described. A selective protection upon the bone marrow as compared with the small intestine and spleen was observed. The comparative protective action of related agents is discussed in detail and an explanation is put forward for the variation in the toxicity of ...
A. J. Therkelsen
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Clinical studies on triethylenephosphoramide and diethylenephosphoramide, compounds with nitrogen-mustard-like activity [PDF]
Cancer, 1953 David A. Karnofsky +3 more
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Attempts at Synthesizing Compounds Isoteric with Methyl-bis-(beta-chloroethyl)amine ("Nitrogen Mustard"). [PDF]
Acta Chemica Scandinavica, 1952 Børge Alhede, K. A. Jensen
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Chemotherapy of leukemia.III. Further studies on the effect of nitrogen mustards and related compounds on transmitted mouse leukemia [PDF]
Cancer, 1951 Joseph H. Burchenal +2 more
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Synthesis of nitrogen mustard-based fluorophores for cell imaging and cytotoxicity studies
Journal of Advanced Pharmaceutical Technology & Research, 2023 Nitrogen mustards are important alkylating anticancer drugs used for neoplasms treatment. However, little research about the integration of luminophore into nitrogen mustard-based compounds for both imaging and therapeutic application was reported.
Yuanwei Liang +5 more
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Degradation of Chemical Warfare Agent Nitrogen Mustard Using Ferrate (VI)
Toxics, 2023 Chemical warfare agents (CWAs) are one of the most toxic compounds. Degradation of CWAs using decontamination agents is one of the few ways to protect human health against the harmful effects of CWAs. A ferrate (VI)-based potential chemical warfare agent
Miroslav Labaška +2 more
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Agronomy, 2022 Utilizing innovative agricultural practices that enhance the nutritional quality of staple foods such as potatoes provides farmers with tools to successfully meet the challenges of feeding a rising global population while sustaining organic food ...
Daniel Temmen, John Randall, Inna Popova
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