3D- and 2D-QSAR models’ study and molecular docking of novel nitrogen-mustard compounds for osteosarcoma [PDF]
Frontiers in Molecular Biosciences, 2023 Background: The dipeptide-alkylated nitrogen-mustard compound is a new kind of nitrogen-mustard derivative with a strong anti-tumor activity, which can be used as a potential anti-osteosarcoma chemotherapy drug.Objective: 2D- and 3D-QSAR (structure ...
Wenkun Zhuo +4 more
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Amino alkyl-alkyl/aryl sulphides (DRDE-07 and analogues) as promising cytoprotectants for sulphur and nitrogen mustards – A review [PDF]
Toxicology ReportsSeveral antidotes and medical countermeasures were experimented for the protection of one of the notorious chemical warfare agents, the mustard gas, also known as sulphur mustard (SM).
R. Vijayaraghavan, M. Sharma
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In Situ Evaluation of the GSH Depletion Ability of Various Alkylating Agents and the Protective Effect of Several Active Thiol Compounds Based on High-Content Cell Analysis [PDF]
ToxicsThe depletion degree of reduced glutathione is a critical indicator for assessing the toxicity of alkylating agents. In the present research, we have developed a novel method to evaluate the glutathione (GSH) depletion induced by a series of alkylating ...
Jing Guo +7 more
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Study on the Reaction Kinetics of Sulfur Mustard, Nitrogen Mustard and Their Chosen Analogues with Sodium Ethoxide [PDF]
MoleculesThe course and kinetics of the reactions of sulfur mustard, nitrogen mustard and their selected analogues with sodium ethoxide were studied using a gas chromatograph coupled with a mass spectrometer.
Klaudia Kozon +3 more
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Synthesis, Clastogenic and Cytotoxic Potential, and In Vivo Antitumor Activity of a Novel N-Mustard Based on Indole-3-carboxylic Acid Derivative [PDF]
MoleculesCompound T1089—a novel nitrogen mustard based on an indole-3-carboxylic acid derivative (ICAD)—has been synthesized. The ICAD used as the basis for T1089 is a TLR agonist capable of activating an antitumor immune response.
Marina Filimonova +12 more
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The Synthesis Of Nitrogen Mustard Derivatives Of Some Steroids And Related Compounds.
, 1952 PhD ; Chemistry ; University of Michigan, Horace H. Rackham School of Graduate Studies ; http://deepblue.lib.umich.edu/bitstream/2027.42/179112/2/0003761 ...
George G. Hazen
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Studies on some cytotoxic compounds of the aromatic nitrogen mustard type
, 1960 Imperial Users ...
G. R. White
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INACTIVATION OF HOG CHOLERA VIRUS : II. INACTIVATION WITH NITROGEN MUSTARD COMPOUNDS
The Japanese Journal of Veterinary Science, 1961 Masao SOEKAWA +5 more
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Attempts at Synthesizing Compounds Isoteric with Methyl-bis-(beta-chloroethyl)amine ("Nitrogen Mustard"). [PDF]
Acta Chemica Scandinavica, 1952 Kai Jensen, Børge Alhede
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