Results 151 to 160 of about 2,356,861 (215)

Potentiation of nitrogen mustard cytotoxicity to leukemia cells by sulfur-containing compounds administered in vivo

International Journal of Radiation Oncology Biology Physics, 1986
Fifteen sulfur-containing compounds were examined for their ability to both protect normal hematopoietic stem cells (NCFU) from the cytotoxic effect of nitrogen mustard (HN2), and potentiate the cytotoxicity of HN2 to AKR leukemia cells (LCFU). All except four agents demonstrated some protection of NCFU with WR-2721 being most active.
Fred Valeriote, F Valeriote
exaly   +3 more sources

Chloroalkyl piperazine and nitrogen mustard porphyrins: synthesis and anticancer activity

open access: yesBioorganic and Medicinal Chemistry, 2004
Fifteen new chloroalkyl piperazine and nitrogen mustard porphyrins have been synthesized by the direct condensation of chloroalkyl piperazine, nitrogen mustard benzaldehyde, and pyrrole. Each porphyrin bears 1-4 chloroalkyl piperazine or nitrogen mustard
Can-Cheng Guo
exaly   +2 more sources

Sulfur and Nitrogen Mustard Carbonate Analogues [PDF]

open access: yesEuropean Journal of Organic Chemistry, 2012
Sulfur and nitrogen half-mustard compounds lose their aggressive properties when the chlorine atom is replaced by a carbonate moiety. The anchimeric effect of the novel mustard carbonate analogues is investigated.
Pietro Tundo, Fabio Aricò
exaly   +2 more sources

New compounds: N-arylglyoxylohydroxamyl derivatives of nitrogen mustard

Journal of Pharmaceutical Sciences, 1967
The synthesis and physical properties of some N,N - bis (2 - chloroethyl)arylglyoxylohy-droxamamides are described.
J P, Larocca, C A, Gibson
openaire   +2 more sources

Phosphorus-nitrogen compounds. 24. Phosphoramide mustard carrier derivatives

Journal of Medicinal Chemistry, 1984
Diethylstilbestrol, psoralen, and propranolol were used as potential carrier molecules for selective concentrations of a nitrogen mustard moiety in breast, skin, and lung tissues, respectively. The propranolol derivative gave two racemic mixtures, which were tested to ascertain any differences in anticancer activity.
L A, Cates   +3 more
openaire   +2 more sources

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