Results 21 to 30 of about 7,217 (188)

Therapeutic Potential of Nitrogen Mustard Based Hybrid Molecules

Frontiers in Pharmacology, 2018
As medicine advances, cancer is still among one of the major health problems, posing significant threats to human health. New anticancer agents features with novel scaffolds and/or unique mechanisms of action are highly desirable for the treatment of ...
Yiming Chen, Yuping Jia, Weiguo Song, Lei Zhang   +3 more
doaj   +1 more source

A Choline Oxidase Amperometric Bioassay for the Detection of Mustard Agents Based on Screen-Printed Electrodes Modified with Prussian Blue Nanoparticles

Sensors, 2015
In this work a novel bioassay for mustard agent detection was proposed. The bioassay is based on the capability of these compounds to inhibit the enzyme choline oxidase.
Fabiana Arduini, Viviana Scognamiglio, Corrado Covaia, Aziz Amine, Danila Moscone, Giuseppe Palleschi   +5 more
doaj   +1 more source

Design, synthesis and in vitro cytotoxicity study of benzodiazepine-mustard conjugates as potential brain anticancer agents

Journal of Saudi Chemical Society, 2017
The combination of two pharmacological entities in a single compound has been utilized as a promising drug design strategy for site-specificity. So two nitrogen mustard agents were synthesized by conjugating mustard with the benzodiazepine nucleus in the
Rajesh K. Singh, D.N. Prasad, T.R. Bhardwaj   +2 more
doaj   +1 more source

Analysis of Volatile Components in Fuling Pickled Mustard Tuber during Spontaneous Fermentation by Non-targeted Metabolomics Based on HS-SPME-GC-MS/MS [PDF]

Shipin Kexue
To investigate the differences in volatile components during the processing of Fuling Zhacai, or pickled mustard tuber, with three stacked layers of mustard tuber and salt, gas chromatography-tandem mass spectrometry (GC-MS/MS)-based non-targeted ...
LU Chunxia, XU Junhao, YU Jie, YOU Xiaohui, CHEN Ya, LI Chaosheng, LI Hongmin, JI Yong, TANG Zonggui, LUO Luyun
doaj   +1 more source

Glutathione S-conjugates as prodrugs to target drug-resistant tumors

Frontiers in Pharmacology, 2014
Living organisms are continuously exposed to xenobiotics. The major phase of enzymatic detoxification in many species is the conjugation of activated xenobiotics to reduced glutathione (GSH) catalyzed by the glutathione-S-transferase (GST).
Emma E. Ramsay, Pierre J. Dilda
doaj   +1 more source

Shifts in Soil Bacterial Communities as a Function of Carbon Source Used During Anaerobic Soil Disinfestation

Frontiers in Environmental Science, 2019
Anaerobic soil disinfestation (ASD) is an organic amendment-based management practice for controlling soil-borne plant pathogens. Pathogen suppression appears to be carbon source-dependent and mediated by bacteria that proliferate and produce volatile ...
Amisha T. Poret-Peterson, Sebastian Albu, Ali E. McClean, Daniel A. Kluepfel   +3 more
doaj   +1 more source

Studies on some cytotoxic compounds of the aromatic nitrogen mustard type

, 1960
Imperial Users ...
G. R. White
openalex   +2 more sources

Sustainable Protein Processing of Flaxseed By‐Product: Nutritional Quality and Functional Properties

Food Frontiers, EarlyView.
Due to its high protein content, flaxseed meal is a promising protein source. Food processing can enhance the protein quality and functional properties of flaxseed meal. Processed flaxseed meal presents low antinutritional factor concentrations, and Lysine is the first limiting amino acid for raw and processed flaxseed meals.
Amanda Gomes Almeida Sá, Maria Teresa Bertoldo Pacheco, Yara Maria Franco Moreno, Bruno Augusto Mattar Carciofi   +3 more
wiley   +1 more source

The key role of local and global farmer networks in the development of conservation agriculture in California

Journal of Environmental Quality, EarlyView.
Abstract This article chronicles the history of California's Conservation Agriculture Systems Innovation (CASI) Center and how it has increased agricultural sustainability in the San Joaquin Valley, a major production area for the United States, by using agroecological practices to reduce soil erosion and conserve soil moisture, champion systems ...
J. P. Mitchell, L. E. Jackson, D. C. Reicosky, A. Kassam, A. Shrestha, R. Harben, E. M. Miyao, K. M. Scow, G. Sposito, D. Beck, T. Friedrich, A. S. Mitchell, R. Schmidt, S. Park, B. Park, P. Foster, P. Muller, A. Brait, T. Willey, M. Bottens, C. Crum, D. Giacomazzi, T. Barcellos, M. V. Crowell, R. Roy, H. Ferris, J. L. Chiartas, E. Brennan, A. Gaudin, John Diener, Justin Diener, L. Asgill, E. A. Kueneman, J. Fisher, M. Bartz, R. A. Peiretti, R. Derpsch, J. Landers, B. J. Aegerter, M. Leinfelder‐Miles, S. E. Light, J. McPhee, R. B. Ferraz Branco   +42 more
wiley   +1 more source

Selenium biofortification: integrating one health and sustainability

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Selenium (Se) biofortification in crops has emerged as a promising strategy to address global Se deficiencies and enhance both agricultural productivity and human health. Increasing the Se content of crops through biofortification improves their resilience to abiotic and biotic stresses and boosts their nutritional value.
Silvia Estarriaga‐Navarro, Nieves Goicoechea, Daniel Plano, Carmen Sanmartín   +3 more
wiley   +1 more source