Results 81 to 90 of about 208 (129)
Stereoselective design of amino acid bioconjugates: targeting strategies and physicochemical optimization. [PDF]
Mandal S, Choudhary R, Konkimalla VB.
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M, Hasegawa, T, Okamoto
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Mutagenicity in yeast of nitroquinolines and related compounds
Toxicology and Applied Pharmacology, 1969Abstract A series of 14 nitroquinolines and hydroxyaminoquinolines, related to the potent water-soluble carcinogen 4-nitroquinoline 1-oxide (4-NQO), were tested for induction of respiratory-deficient mutants in Saccharomyces cerevisiae . Eight quinolines, including 4-NQO and 4-hydroxyaminoquinoline 1-oxide, were mutagenic at concentrations markedly ...
S S Epstein
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Oxidative Methylamination of Nitroquinolines
Liebigs Annalen der Chemie, 1993Abstract3‐, 5‐, 6‐, 7‐ and 8‐nitroquinoline as well as 5,7‐ and 6,8‐dinitroquinoline are methylaminated with a liquid methylamine solution of potassium permanganate (LMA/PP) to the corresponding mono‐ and bis(methylamino)‐substituted compounds. 2‐Nitroquinoline is aminated with LMA/PP to 2‐(methylamino)quinoline.
Marian Woźniak, Maria Grzegożek
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Synthesis of polyfluorinated aminoquinolines via nitroquinolines
Journal of Fluorine Chemistry, 2018Abstract Transformation of 14 quinolines polyfluorinated in the benzene moiety was investigated in nitration systems: a mixture of HNO3 and H2SO4, NaNO3 in H2SO4, NO2BF3OH in sulfolane, or NaNO3 in oleum. 5-Nitro- and/or 8-nitro derivatives formed if positions 5 or 8 were unoccupied in the starting compounds.
Irina Bagryanskaya +2 more
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Methods for the Synthesis of Nitroquinolines (A Review)
Russian Journal of Organic Chemistryexaly +2 more sources
Substituent effect of a fluorine atom on the mutagenicity of nitroquinolines
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1999Some 16 nitroquinolines (NQs) and their fluorinated derivatives were tested for mutagenicity in Salmonella typhimurium TA100 without S9 mix to investigate the effect of fluorine-substitution on the mutagenicity. These NQs consist of 5-NQs, 5-nitroquinoline N-oxides (5-NQOs), N-methyl-5-nitroquinolinium methanesulfonates (N-Me-5-NQs) and 8-NQs ...
K, Saeki +6 more
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Technology of Preparing 8‐Hydroxy‐5‐nitroquinoline.
ChemInform, 2005AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. A. Isaev +3 more
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Carcinogenicity of 8-nitroquinoline in Sprague—Dawley rats
Cancer Letters, 19788-Nitroquinoline was added to the semisynthetic diet of outbred Sprague-Dawley rats for 48 weeks. Squamous cell carcinomas of the upper digestive tract (tongue and esophagus), but especially of the forestomach, occurred among the higher concentration groups.
M, Takahashi +5 more
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