Results 81 to 90 of about 208 (129)

Mutagenicity in yeast of nitroquinolines and related compounds

Toxicology and Applied Pharmacology, 1969
Abstract A series of 14 nitroquinolines and hydroxyaminoquinolines, related to the potent water-soluble carcinogen 4-nitroquinoline 1-oxide (4-NQO), were tested for induction of respiratory-deficient mutants in Saccharomyces cerevisiae . Eight quinolines, including 4-NQO and 4-hydroxyaminoquinoline 1-oxide, were mutagenic at concentrations markedly ...
S S Epstein
exaly   +3 more sources

Oxidative Methylamination of Nitroquinolines

Liebigs Annalen der Chemie, 1993
Abstract3‐, 5‐, 6‐, 7‐ and 8‐nitroquinoline as well as 5,7‐ and 6,8‐dinitroquinoline are methylaminated with a liquid methylamine solution of potassium permanganate (LMA/PP) to the corresponding mono‐ and bis(methylamino)‐substituted compounds. 2‐Nitroquinoline is aminated with LMA/PP to 2‐(methylamino)quinoline.
Marian Woźniak, Maria Grzegożek
openaire   +1 more source

Synthesis of polyfluorinated aminoquinolines via nitroquinolines

Journal of Fluorine Chemistry, 2018
Abstract Transformation of 14 quinolines polyfluorinated in the benzene moiety was investigated in nitration systems: a mixture of HNO3 and H2SO4, NaNO3 in H2SO4, NO2BF3OH in sulfolane, or NaNO3 in oleum. 5-Nitro- and/or 8-nitro derivatives formed if positions 5 or 8 were unoccupied in the starting compounds.
Irina Bagryanskaya   +2 more
exaly   +2 more sources

Substituent effect of a fluorine atom on the mutagenicity of nitroquinolines

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 1999
Some 16 nitroquinolines (NQs) and their fluorinated derivatives were tested for mutagenicity in Salmonella typhimurium TA100 without S9 mix to investigate the effect of fluorine-substitution on the mutagenicity. These NQs consist of 5-NQs, 5-nitroquinoline N-oxides (5-NQOs), N-methyl-5-nitroquinolinium methanesulfonates (N-Me-5-NQs) and 8-NQs ...
K, Saeki   +6 more
openaire   +2 more sources

Technology of Preparing 8‐Hydroxy‐5‐nitroquinoline.

ChemInform, 2005
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
A. A. Isaev   +3 more
openaire   +1 more source

Carcinogenicity of 8-nitroquinoline in Sprague—Dawley rats

Cancer Letters, 1978
8-Nitroquinoline was added to the semisynthetic diet of outbred Sprague-Dawley rats for 48 weeks. Squamous cell carcinomas of the upper digestive tract (tongue and esophagus), but especially of the forestomach, occurred among the higher concentration groups.
M, Takahashi   +5 more
openaire   +2 more sources

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