Results 11 to 20 of about 13,078 (157)

Selective, Oxygen-Tunable, and Metal-Free Functionalization of Polyethylene Through Dual-Mode Nitrosation and Carbonylation. [PDF]

Angew Chem Int Ed Engl
A metal‐free nitrosation process enables direct C–H functionalization of polyethylene (PE) with high selectivity, producing either oxime‐ or carbonyl‐functionalized polymers. Using t‐BuONO under visible light or thermal conditions, the process operates in both lab‐scale and industrial settings.
Cluzeau L, Robert F, Bassani DM, Landais Y, Taton D.   +4 more
europepmc   +3 more sources

Quercetin Enhances Gastric Nitric Oxide Formation and Potentiates the Antihypertensive Effects of Oral Nitrite Administration. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Oral nitrite supplementation enhances nitric oxide (NO) bioavailability and lowers blood pressure. Quercetin may facilitate the reduction of nitrite to NO. However, the combined effects of nitrite and Quercetin on gastric NO formation and blood pressure have not been explored.
Silva-Cunha M, Conde-Tella SO, Rebelo MA, Kemmer ILM, Lima-Silva AK, Caetano ESP, Tanus-Santos JE.   +6 more
europepmc   +2 more sources

Drug Discovery Applications of Nitroso (Hetero)Arene Derivatives. [PDF]

Chempluschem
Nitroso (hetero)aromatic compounds are bioactive molecules with antiviral, anticancer, neuroprotective, and antimicrobial properties. This review highlights their mechanisms of action—oxidative stress, DNA damage, and enzyme inhibition—alongside synthesis, structure–activity relationships, and toxicity challenges, offering insight into their ...
Roscales S, Csáky AG.
europepmc   +2 more sources

Multifaceted Effects of a Multiple Nitric Oxide Photoreleaser and its Photoproducts on Amyloid-β Aggregation. [PDF]

Chembiochem
A blue light‐activatable NO photodonor sequentially releases two NO molecules accompanied by two stable photoproducts, showing differentiated effects on the β‐amyloid aggregation. Aberrant aggregation of β‐amyloid (Aβ) peptides into insoluble fibrils is recognized as one of the hallmarks of Alzheimer's disease (AD).
Laneri F, Parisi C, Sortino S.
europepmc   +2 more sources

The key role of nitric oxide in hypoxia: hypoxic vasodilation and energy supply-demand matching [PDF]

, 2013
Significance: a mismatch between energy supply and demand induces tissue hypoxia with the potential to cause cell death and organ failure. Whenever arterial oxygen concentration is reduced, increases in blood flow - 'hypoxic vasodilation' - occur in an ...
Alex Dyson, Audibert G, Berne RM, Blitzer ML, Boutilier RG, Brown IP, Devlin C, Furukawa K, Hall JE, Heyes MP, Jekabsone A, Lehninger A, Leone AM, Louis CA, Martin Feelisch, Mervyn Singer, Michele Umbrello, Modin A, Munk VC, Pohl U, Rengasamy A, Rengasamy A, Vallance P, Whorton AR   +23 more
core   +1 more source

A further study of acetylacetone nitrosation [PDF]

, 2013
The nitrosation of acetylacetone (AcAc) has been revised in an aqueous acid medium of perchloric acid and buffers of mono-, di-, or tri-chloroacetic acid.
Brandariz, Isabel, Iglesias, Emilia
core   +2 more sources

Urinary levels of N-nitroso compounds in relation to risk of gastric cancer: Findings from the Shanghai cohort study [PDF]

, 2015
Background: N-Nitroso compounds are thought to play a significant role in the development of gastric cancer. Epidemiological data, however, are sparse in examining the associations between biomarkers of exposure to N-nitroso compounds and the risk of ...
A Jemal, AJ Cross, AR Tricker, AR Tricker, C La Vecchia, CA Gonzalez, CL Sun, D Pobel, DM Parkin, DR Scott, E De Stefani, FD Ji, G De Bernardinis, H Ohshima, H Ohshima, H Ohshima, H Suzuki, Heather H. Nelson, JC Lunn, JE Stuff, Jeffrey S Chang, JG Kusters, JH Hotchkiss, Jian-Min Yuan, JM van Maanen, JM Yuan, JM Yuan, JM Yuan, JS Griesenbeck, KA Moy, Ling Xu, M Carboni, M McCracken, NE Breslow, NP Sen, P Jakszyn, P Jakszyn, P Knekt, R Schoental, Renwei Wang, RK Ross, S Calmels, SL He, SS Mirvish, T Herod-Leszczynska, W Lijinsky, Xin-Di Chu, Y Grosse, Yong-Hua Qu, Yu-Tang Gao   +49 more
core   +7 more sources

Nitrosylation of Myoglobin and Nitrosation of Cysteine by Nitrite in a Model System Simulating Meat Curing [PDF]

, 2012
Demand is growing for meat products cured without the addition of sodium nitrite. Instead of the direct addition of nitrite to meat in formulation, nitrite is supplied by bacterial reduction of natural nitrate often added as vegetable juice/powder ...
AOAC, Binkerd E. F., Cassens R. G., Dangour A. D., Dautrevaux M., Ellman G. L., Ender F., Food and Drug Administration (FDA), Ford P. C., Fox J. B., Fox J. B. J., Gamgee A., Gary A. Sullivan, Giddings G. G., Haldane J., Henry Y. A., Hughner R. S., Jackson A. L., Joseph G. Sebranek, Kanner J., Kemp J. D., Killday K. B., Koppang N., Lewis W. L., Loke K. E., Lundberg J. O., Magnusson M. K., Miersch S., Nunes K., O'Leary V., Peterson L. A., Rehder D. S., Rodriguez J., Sebranek J. G., Sebranek J. G., Shiva S., Sindelar J. J., Tompkin R. B., U.S. Department of Agriculture (USDA), United States Department of Agriculture (USDA), United States Department of Agriculture (USDA), Williams D. L. H., Winter C. K., Woolford G., Woolford G., Xi Y.   +45 more
core   +3 more sources

Detection of reactive oxygen and nitrogen species by electron paramagnetic resonance (EPR) technique [PDF]

, 2017
During the last decade there has been growing interest in physical-chemical oxidation processes and the behavior of free radicals in living systems. Radicals are known as intermediate species in a variety of biochemical reactions.
Gurer-Orhan, H., Saso, L., Suzen, S.
core   +2 more sources

S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration [PDF]

, 2016
Protein S-nitrosation (SNO-protein), the nitric oxide-mediated posttranslational modification of cysteine thiols, is an important regulatory mechanism of protein function in both physiological and pathological pathways.
Bhat, Vadiraja B., Nott, Alexi, Ravindra, Kodihalli C., Seneviratnea, Uthpala, Tannenbaum, Steven R, Tsai, Li-Huei, Wishnok, John S   +6 more
core   +1 more source