Results 11 to 20 of about 7,232 (217)

S-Nitrosation and Ubiquitin-Proteasome System Interplay in Neuromuscular Disorders [PDF]

International Journal of Cell Biology, 2014
Protein S-nitrosation is deemed as a prototype of posttranslational modifications governing cell signaling. It takes place on specific cysteine residues that covalently incorporate a nitric oxide (NO) moiety to form S-nitrosothiol derivatives and depends
Salvatore Rizza, Costanza Montagna, Giuseppina Di Giacomo, Claudia Cirotti, Giuseppe Filomeni   +4 more
doaj   +2 more sources

Nitrosation of dietary precursors. [PDF]

Cancer surveys, 1989
The diet contains a large number of constituents which can be nitrosated in the gastrointestinal tract (especially in the stomach) to potentially carcinogenic nitroso compounds (NOC). The nitrosation of food mixtures has been investigated with a number of assays, such as chemical analysis or detection of alkylating potential, mutagenicity and ...
Shephard, S. E., Lutz, Werner K.
openaire   +4 more sources

Safe by Design Flow Technology for Diazoacetonitrile Generation and Direct Conversion to Pyrazoles. [PDF]

ChemistryOpen
A safe by design flow process generates diazoacetonitrile (DAN) in water, transfers it with minimal hold up into an organic phase, and immediately consumes it in a telescoped [3 + 2] cycloaddition. Mapping of solvent, temperature, pressure, and residence time windows enables controlled DAN handling and practical access to cyanopyrazoles.
Bošković D, Loebbecke S, Piscopo CG, Radulescu LJ, Schwarzer M.   +4 more
europepmc   +2 more sources

Encapsulated Reagents for Nitrosation. [PDF]

ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
Grigory V, Zyryanov, Dmitry M, Rudkevich
openaire   +2 more sources

A Versatile New Reagent for Nitrosation under Mild Conditions [PDF]

, 2021
We report a new chemical reagent for transnitrosation under mild experimental conditions. This new reagent is stable to air and moisture across a broad range of temperatures, and is effective for transnitrosation in multiple solvents.
Ryan, Baxter, Hrant, Hratchian, James C., Fettinger, Cristian, Sarabia, Jordan D., Galloway   +4 more
core   +1 more source

Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation [PDF]

, 2007
<b>Background</b>: The major potential site of acid nitrosation is the proximal stomach, an anatomical site prone to a rising incidence of metaplasia and adenocarcinoma.
Paterson, S., Crozier, A., Winter, J., Iijima, K., Preston, T., Combet, E., Mullen, W., McColl, K.E.L.   +7 more
core   +1 more source

Decomposition Kinetics of Solution and Lyophilized Powder of S-Nitroso-N-Cetylcysteine. [PDF]

J Food Sci
ABSTRACT Recently, S‐nitrosothiols (RSNO) have received increased attention in the food industry as replacements for nitrite salts in meat products. However, their industrial applications are limited because of their high instability in concentrated aqueous solutions.
Andrade BF, Carmo LRD, da Silva VM, Filho RAT, Fontes PR, Ramos ALS, Ramos EM.   +6 more
europepmc   +2 more sources

Redox-sensitivity and site-specificity of S- and N- denitrosation in proteins [PDF]

, 2010
Background S-nitrosation – the formation of S-nitrosothiols (RSNOs) at cysteine residues in proteins – is a posttranslational modification involved in signal transduction and nitric oxide (NO) transport.
Park Joo-Ho, Bhagavan Nadhipuram V., Fernandez Bernadette O., David Jourd'heuil, Ha Chung-Eun, Lowery Anthony M., Feelisch, Martin, Frances L Jourd'heuil, Sanie Mnaimneh, Jourd'heuil Frances L., Melton Elaina M., Bhagavan, Nadhipuram V., Chung-eun Ha, Martin Feelisch, Ha, Chung-Eun, Elaina M Melton, Fernandez, Bernadette O., Jourd'heuil David, Bauer, Joseph Alan, Feelisch Martin, Bryan, Nathan S., Jourd'heuil, David, Park, Joo-Ho, Nathan S Bryan, Nadhipuram V Bhagavan, Nadhipuram V. Bhagavan, Lowery, Anthony M., Melton, Elaina M., Anthony M. Lowery, Frances L. Jourd’heuil, Bernadette O Fernandez, Mnaimneh Sanie, Elaina M. Melton, Joo-ho Park, Anthony M Lowery, Bernadette O. Fern, Frances L. Jourd'heuil, Mnaimneh, Sanie, Nathan S. Bryan, Bryan Nathan S., Bernadette O. Fernandez, Jourd'heuil, Frances L.   +41 more
core   +1 more source

The Peroxidatic Thiol of Peroxiredoxin 1 is Nitrosated by Nitrosoglutathione but Coordinates to the Dinitrosyl Iron Complex of Glutathione

Antioxidants, 2020
Protein S-nitrosation is an important consequence of NO●·metabolism with implications in physiology and pathology. The mechanisms responsible for S-nitrosation in vivo remain debatable and kinetic data on protein S-nitrosation by different agents ...
Daniela R. Truzzi, Simone V. Alves, Luis E. S. Netto, Ohara Augusto   +3 more
doaj   +1 more source

Losartan API and Nitrosamines Impurities-Stability Profile Investigation Using HPLC, LC-MS, and In Silico Assessment. [PDF]

J Sep Sci
ABSTRACT Nitrosamines are potent genotoxic impurities with well reported mutagenic and carcinogenic effects. Their presence has been detected in several pharmaceutical products among them losartan, an angiotensin II receptor blocker. Considering the risks already reported for these impurities, the present study aimed to investigate the influence of ...
Martini PRR, Machioli LF, Santos BPD, Oliveira TF, Paula FR, Paim CS, Mendez ASL.   +6 more
europepmc   +2 more sources