Results 41 to 50 of about 13,078 (157)

Meat processing and colon carcinogenesis: Cooked, nitrite-treated and oxidized high-heme cured meat promotes mucin depleted foci in rats [PDF]

, 2010
Processed meat intake is associated with colorectal cancer risk, but no experimental study supports the epidemiologic evidence. To study the effect of meat processing on carcinogenesis promotion, we first did a 14-day study with 16 models of cured meat ...
Caderni, Claude Genot, Cross, Cummings, Denis E. Corpet, Estevez, Fabrice H.F. Pierre, Françoise Guéraud, Jean-Luc Vendeuvre, Kälble, Lethuaut, Linseisen, Michelle Viau, Mirvish, Mirvish, Nathalie Naud, Parnaud, Pierre, Pierre, Pierre, Raphaëlle L. Santarelli, Sandhu, Sawa, Sesink, Shahidi, Sinha, Sylviane Taché   +26 more
core   +4 more sources

Total Synthesis of the Cyanobacterial Alkaloid Nostodione A

European Journal of Organic Chemistry, Volume 29, Issue 2, January 16, 2026.
The total synthesis of the alkaloid nostodione A is successfully achieved utilizing 3,4‐dihydrocyclopenta[b]indole‐1,2‐dione as a key intermediate. The sensitive benzylidene moiety is introduced via a Knoevenagel condensation with p‐hydroxybenzaldehyde.
Oscar F. Casadiego‐Díaz, Ángel Rentería‐Gómez, Teresa Ramírez‐Apan, Rubén O. Torres‐Ochoa   +3 more
wiley   +1 more source

1,4-Bis(4-nitrosophenyl)piperazine: novel bridging ligand in dinuclear complexes of rhodium(III) and iridium(III). [PDF]

, 2012
The synthesis, spectroscopic characterization and crystal structures of the first 1,4-bis(4-nitrosophenyl)piperazine (BNPP) (4) bridged dinuclear complexes of rhodium(III) and iridium(III) are presented. The reaction of the μ2-halogenido-bridged dimers [(
Barth, Florian, Lorenz, Ingo-Peter, Wirth, Stefan   +2 more
core   +1 more source

Crucial Role of Oxidation for the Prebiotic Peptide Elongation Promoted by Carbonyl Sulfide

European Journal of Organic Chemistry, Volume 29, Issue 1, January 12, 2026.
The prebiotic activation of amino acid (AA) into peptides via N‐carboxyanhydride (NCA), promoted by carbonyl sulfide (COS), cannot proceed without an oxidizing step (enabling better leaving groups than sulfur dianion). While being efficient even at mild pH the prebiotic scope of COS promoted activation of AA, it is however limited because side ...
Alexandre Desfoux, Jean‐Christophe Rossi, Laurent Boiteau, Gaulthier Rydzek, Robert Pascal   +4 more
wiley   +1 more source

Une réévaluation de la methode d'incorporation de H14C03- pour mesurer la nitrification autotrophe et son application pour estimer des biomasses de bactéries nitrifiantes [PDF]

, 1998
Le processus de nitrification joue un rôle essentiel dans le cycle de l'azote dans les milieux aquatiques naturels. La mesure de l'activité nitrifiante est une étape obligée pour bien comprendre et quantifier les flux d'azote dans ces milieux. Ce travail
Billen, G., Brion, N.
core   +1 more source

Freeze-Dried Ham Promotes Azoxymethane-Induced Mucin-Depleted Foci and Aberrant Crypt Foci in Rat Colon [PDF]

, 2010
Processed and red meat consumption is associated with the risk of colorectal cancer. Meta-analyses have suggested that the risk associated with processed meat is higher. Most processed meats are cured and cooked, which leads to formation of free nitrosyl
Bonneson C, Caderni G, Cross A J, Cummings J H, Denis E. Corpet, Fabrice H. F. Pierre, Françoise Guéraud, Karkare M R, Nathalie Naud, Ossama Allam, Pierre F, Raphaëlle L. Santarelli, Sandhu M S, Sesink A LA, Sinha R, Sylviane Taché, Van Den Berg J W   +16 more
core   +4 more sources

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury [PDF]

, 2014
Background Many diseases and pathological conditions are characterized by transient or constitutive overproduction of reactive oxygen species (ROS).
Ashraf, Muhammad Imtiaz, Brandacher, Gerald, Dragun, Duska, Ebner, Matthias, Enthammer, Marion, Haller, Martina, Hermann, Martin, Khalid, Sana, Koziel, Katarzyna, Santer, Peter, Schwelberger, Hubert, Sickinger, Stephan, Soleiman, Afschin, Steger, Christina, Sucher, Robert, Troppmair, Jakob, Vallant, Stephanie, Wallner, Christoph   +17 more
core   +2 more sources

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

British Journal of Pharmacology, Volume 183, Issue 1, Page 40-56, January 2026.
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue, Sophia K. Heuser, Marla Lindemann, Junjie Li, Masudur Rahman, Malte Kelm, Johannes Stegbauer, Miriam M. Cortese‐Krott   +7 more
wiley   +1 more source

Interactions between cell surface protein disulphide isomerase and S-nitrosoglutathione during nitric oxide delivery [PDF]

, 2007
In this study, we investigated the role of protein disulphide isomerase (PDI) in rapid metabolism of S-nitrosoglutathione (GSNO) and S-nitrosoalbumin (albSNO) and in NO delivery from these compounds into cells.
Askew, Burgess, C.M. Shah, Chen, Cooper, Crane, Crane, de Belder, Essex, Essex, Freedman, Gordge, Gordge, H.S. Chowdrey, Hogg, Hogg, Hogg, I.C. Locke, Jordan, Lahav, Lipton, Liu, Liu, M.P. Gordge, Ogura, O’Neill, Park, Park, Pfeiffer, Ramachandran, Richardson, Root, S.E. Bell, Shah, Simon, Sogo, Stamler, Walsh, Yan, Zai, Zeng, Zhang, Zhang   +42 more
core   +1 more source

Non‐canonical nitric oxide signalling and DNA methylation: Inflammation induced epigenetic alterations and potential drug targets

British Journal of Pharmacology, Volume 183, Issue 1, Page 24-39, January 2026.
Abstract DNA methylation controls DNA accessibility to transcription factors and other regulatory proteins, thereby affecting gene expression and hence cellular identity and function. As epigenetic modifications control the transcriptome, epigenetic dysfunction is strongly associated with pathological conditions and ageing.
Christopher H. Switzer
wiley   +1 more source