Results 41 to 50 of about 4,320,383 (194)
Remarkable interest has risen in the idea that oxidative/nitrosative stress is mediated in the etiology of numerous human diseases. Oxidative/Nitrosative stress is the result of an disequilibrium in oxidant/antioxidant which reveals from continuous ...
E. Kurutaş
semanticscholar +1 more source
Neuro-oxidative-nitrosative stress in sepsis [PDF]
Neuro-oxidative-nitrosative stress may prove the molecular basis underlying brain dysfunction in sepsis. In the current review, we describe how sepsisinduced reactive oxygen and nitrogen species (ROS/RNS) trigger lipid peroxidation chain reactions throughout the cerebrovasculature and surrounding brain parenchyma, due to failure of the local ...
Berg, Ronan M G +2 more
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Regulation of Apoptosis by Nitrosative Stress [PDF]
Nitrosative stress can prevent or induce apoptosis. It occurs via S-nitrosylation by the interaction of nitric oxide (NO) with the biological thiols of proteins. Cellular redox potential and non-heme iron content determine S-nitrosylation. Apoptotic cell death is inhibited by S-nitrosylation of the redox-sensitive thiol in the catalytic site of caspase
Ki-Mo, Kim +5 more
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Nitrosative Stress and Human Disease: Therapeutic Potential of Denitrosylation
Proteins dynamically contribute towards maintaining cellular homeostasis. Posttranslational modification regulates the function of target proteins through their immediate activation, sudden inhibition, or permanent degradation.
Somy Yoon, G. Eom, Gaeun Kang
semanticscholar +1 more source
Does Oxidative Stress Change During Orthotopic Liver Transplantation?
In clinical ischemia/reperfusion injury, damage resulting from oxidative and nitrosative stress is generally considered crucial for graft functioning.
Dimitrios Tsikas
doaj +1 more source
Excess production of nitric oxide (NO) and reactive nitrogen intermediates (RNIs) causes nitrosative stress on cells. Schizosaccharomyces pombe was used as a model to study nitrosative stress response.
Pranjal Biswas +2 more
doaj +1 more source
iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. [PDF]
Nitrosative stress compromises force generation in Duchenne muscular dystrophy (DMD). Both inducible nitric oxide synthase (iNOS) and delocalized neuronal NOS (nNOS) have been implicated.
Dejia Li, Jin-Hong Shin, Dongsheng Duan
doaj +1 more source
Nitrosative Stress and Its Association with Cardiometabolic Disorders
Reactive nitrogen species (RNS) are formed when there is an abnormal increase in the level of nitric oxide (NO) produced by the inducible nitric oxide synthase (iNOS) and/or by the uncoupled endothelial nitric oxide synthase (eNOS).
I. Pérez-Torres +4 more
semanticscholar +1 more source
Alzheimer’s disease (AD) is the most common form of dementia worldwide, being characterized by the deposition of senile plaques, neurofibrillary tangles (enriched in the amyloid beta (Aβ) peptide and hyperphosphorylated tau (p-tau), respectively) and ...
A. Duarte +9 more
semanticscholar +1 more source
The metabolic reprogramming evoked by nitrosative stress triggers the anaerobic utilization of citrate in Pseudomonas fluorescens. [PDF]
Nitrosative stress is an ongoing challenge that most organisms have to contend with. When nitric oxide (NO) that may be generated either exogenously or endogenously encounters reactive oxygen species (ROS), it produces a set of toxic moieties referred to
Christopher Auger +4 more
doaj +1 more source

