Results 51 to 60 of about 4,320,383 (194)

Nitrosative stress induced cytotoxicity in Giardia intestinalis [PDF]

Journal of Applied Microbiology, 2003
To investigate the antigiardial properties of the nitrosating agents: sodium nitrite, sodium nitroprusside and Roussin's black salt.Use of confocal laser scanning microscopy and flow cytometry indicated permeabilization of the plasma membrane to the anionic fluorophore, DiBAC4(3) [bis(1,3-dibutylbarbituric acid) trimethine oxonol].
Lloyd, D, Harris, J C, Maroulis, S, Mitchell, A, Hughes, M N, Wadley, R B, Edwards, M R   +6 more
openaire   +3 more sources

The Effect of N-Acetylcysteine on Respiratory Enzymes, ADP/ATP Ratio, Glutathione Metabolism, and Nitrosative Stress in the Salivary Gland Mitochondria of Insulin Resistant Rats

Nutrients, 2020
This is the first study to assess the effect of N-acetylcysteine (NAC) on the mitochondrial respiratory system, as well as free radical production, glutathione metabolism, nitrosative stress, and apoptosis in the salivary gland mitochondria of rats with ...
A. Zalewska, I. Szarmach, M. Żendzian-Piotrowska, M. Maciejczyk   +3 more
semanticscholar   +1 more source

Doxorubicin-induced oxidative and nitrosative stress: Mitochondrial connexin 43 is at the crossroads

International Journal of Molecular Medicine, 2020
Oxidative stress is widely accepted as a key factor of doxorubicin (Doxo)-induced cardiotoxicity. There is evidence to indicate that nitrosative stress is involved in this process, and that Doxo interacts by amplifying cell damage. Mitochondrial connexin
M. Pecoraro, Barbara Pala, M. C. Di Marcantonio, R. Muraro, S. Marzocco, A. Pinto, G. Mincione, A. Popolo   +7 more
semanticscholar   +1 more source

Oxidative and Nitrosative Stress and Fibrogenic Response [PDF]

Clinics in Liver Disease, 2008
Uncontrolled production of collagen I is the main feature of liver fibrosis. Following a fibrogenic stimulus such as alcohol, hepatic stellate cells (HSC) transform into an activated collagen-producing cell. In alcoholic liver disease, numerous changes in gene expression are associated with HSC activation, including the induction of several ...
R, Urtasun, L, Conde de la Rosa, N, Nieto   +2 more
openaire   +2 more sources

A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria

Frontiers in Microbiology, 2017
Mycobacterium tuberculosis has the ability to survive inside macrophages under acid-nitrosative stress. M. tuberculosis Rv1685c and its ortholog in M. smegmatis, MSMEG_3765, are induced on exposure to acid-nitrosative stress.
Filomena Perrone, Barbara De Siena, Lidia Muscariello, Sharon L. Kendall, Simon J. Waddell, Margherita Sacco   +5 more
doaj   +1 more source

Manganese import protects Salmonella enterica serovar Typhimurium against nitrosative stress.

Metallomics, 2020
Nitric oxide (NO˙) is a radical molecule produced by mammalian phagocytic cells as part of the innate immune response to bacterial pathogens. It exerts its antimicrobial activity in part by impairing the function of metalloproteins, particularly those ...
Shehla Yousuf, J. Karlinsey, S. L. Neville, C. McDevitt, S. Libby, F. Fang, E. Frawley   +6 more
semanticscholar   +1 more source

S-Glutathionylation of metallothioneins by nitrosative/oxidative stress

Experimental Gerontology, 2008
Cystein residues within metallothionein (MT) structure have been shown to be particularly prone to S-nitrosylation. The objective of this study was to examine the possibility that MTs undergo S-glutathionylation under nitrosative/oxidative stress. MT from rabbit liver was treated with different concentrations of GSNO, diamide plus GSH or H(2)O(2) plus ...
CASADEI M, PERSICHINI T, POLTICELLI F, MUSCI, Giovanni, COLASANTI M.   +4 more
openaire   +5 more sources

Role of AP-1 transcriptional factor in development of oxidative and nitrosative stress in periodontal tissues during systemic inflammatory response

Ukrainian Biochemical Journal, 2019
Chronic systemic inflammatory response syndrome (SIRS) underlies many diseases (sepsis, atherosclerosis, diabetes mellitus). According to research data of recent years the key role in the development of SIRS is played by the activation of various nuclear
A. M. Yelins’ka, O. Akimov, V. Kostenko   +2 more
semanticscholar   +1 more source

A Novel Mechanism for Nitrosative Stress Tolerance Dependent on GTP Cyclohydrolase II Activity Involved in Riboflavin Synthesis of Yeast

Scientific Reports, 2020
The biological functions of nitric oxide (NO) depend on its concentration, and excessive levels of NO induce various harmful situations known as nitrosative stress.
K. Anam, Ryo Nasuno, H. Takagi
semanticscholar   +1 more source

Cellular responses of Candida albicans to phagocytosis and the extracellular activities of neutrophils are critical to counteract carbohydrate starvation, oxidative and nitrosative stress.

PLoS ONE, 2012
Neutrophils are key players during Candida albicans infection. However, the relative contributions of neutrophil activities to fungal clearance and the relative importance of the fungal responses that counteract these activities remain unclear.
Pedro Miramón, Christine Dunker, Hanna Windecker, Iryna M Bohovych, Alistair J P Brown, Oliver Kurzai, Bernhard Hube   +6 more
doaj   +1 more source