Results 71 to 80 of about 25,127 (201)

Klotho protein alleviates heart ischemia/reperfusion injury and oxidative stress through regulation of the NOS/MMP pathway

Scientific Reports
Heart ischemia/reperfusion injury (IRI) significantly contributes to cardiac damage through oxidative and nitrosative stress, where the dysregulation of nitric oxide synthases (NOS) and the subsequent activation of matrix metalloproteinases (MMPs) are ...
Agnieszka Olejnik, Anna Krzywonos-Zawadzka, Izabela Sambor, Andrzej Mysiak, Iwona Bil-Lula   +4 more
doaj   +1 more source

May the Nitrosative and Carbonyl Stress Promote Inflammation in Patients with Colorectal Cancer?

Journal of Inflammation Research, 2022
Justyna Dorf,1 Konrad Zaręba,2 Joanna Matowicka-Karna,1 Anna Pryczynicz,3 Katarzyna Guzińska-Ustymowicz,3 Anna Zalewska,4 Mateusz Maciejczyk5 1Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Bialystok, Poland;
Dorf J, Zaręba K, Matowicka-Karna J, Pryczynicz A, Guzińska-Ustymowicz K, Zalewska A, Maciejczyk M   +6 more
doaj  

The ComEA/ComEC Operon is Critical for Nitrosative Stress Tolerance by an Oral Commensal

Molecular Oral Microbiology, EarlyView.
ABSTRACT Oral commensal streptococci play a large role in mediating microbial homeostasis. Our prior work has demonstrated that hydrogen peroxide (H2O2) produced by oral commensal streptococci can react with salivary nitrite (NO2) and generate peroxynitrite (ONOO−), a potent antimicrobial.
Sara E. Edmonds, Hernan Grenett, Priscilla Grenett, Jessica A. Scoffield   +3 more
wiley   +1 more source

Metabolic syndrome components are associated with oxidative stress in overweight and obese patients

Archives of Endocrinology and Metabolism, 2018
Objective: The aim of this study is to evaluate the influence of the body mass index (BMI) and the metabolic syndrome (MetS) parameters on oxidative and nitrosative stress in overweight and obese subjects.
Nayara Rampazzo Morelli, Bruna Miglioranza Scavuzzi, Lucia Helena da Silva Miglioranza, Marcell Alysson Batisti Lozovoy, Andréa Name Colado Simão, Isaias Dichi   +5 more
doaj   +1 more source

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Nitrosative stress in human spermatozoa causes cell death characterized by induction of mitochondrial permeability transition-driven necrosis

Asian Journal of Andrology, 2018
Peroxynitrite is a highly reactive nitrogen species and a potent inducer of apoptosis and necrosis in somatic cells. Peroxynitrite-induced nitrosative stress has emerged as a major cause of impaired sperm function; however, its ability to trigger cell ...
Pamela Uribe, María E Cabrillana, Miguel W Fornés, Favián Treulen, Rodrigo Boguen, Vladimir Isachenko, Evgenia Isachenko, Raúl Sánchez, Juana V Villegas   +8 more
doaj   +1 more source

Differential intestinal injury and unchanged systemic inflammatory responses to leg and whole‐body passive hyperthermia in healthy humans

Experimental Physiology, EarlyView.
Abstract Hyperthermia can cause intestinal injury, facilitating endotoxin translocation and an inflammatory response that has been associated with heat illness. However, the potential occurrence of these responses has been incompletely reported during passive hyperthermia, and the independent effect of hyperthermia is equivocal.
Oliver R. Gibson, Orlando Laitano, Kazuhito Watanabe, José González‐Alonso   +3 more
wiley   +1 more source

nitrosative stress

Citation: 'nitrosative stress' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.15918 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

Experimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris, Anton Trask‐Marino, Alemayehu Jufar, Ashenafi H. Betrie, Adam Southon, Sally G. Hood, Rinaldo Bellomo, Abraham H. Hulst, Clive N. May, Connie P. C. Ow, Yugeesh R. Lankadeva   +10 more
wiley   +1 more source

Nitrosative and oxidative stress responses in fungal pathogenicity

Current Opinion in Microbiology, 2009
Fungal pathogenicity has arisen in polyphyletic manner during evolution, yielding fungal pathogens with diverse infection strategies and with differing degrees of evolutionary adaptation to their human host. Not surprisingly, these fungal pathogens display differing degrees of resistance to the reactive oxygen and nitrogen species used by human cells ...
Brown, Alistair JP, Haynes, Ken, Quinn, Janet   +2 more
openaire   +2 more sources