Results 11 to 20 of about 32,433 (236)

Synthesis of Nitroxide Diradical Using a New Approach [PDF]

Molecules, 2020
A new synthetic pathway to diradical organic systems is proposed. The effectiveness of this approach was exemplified by the synthesis of a new nitroxide diradical. An interaction of perfluorobiphenyl with lithium tert-butylamide, followed by oxidation of
Pavel Fedyushin, Tatyana Rybalova, Nargiz Asanbaeva, Elena Bagryanskaya, Alexey Dmitriev, Nina Gritsan, Maxim Kazantsev, Evgeny Tretyakov   +7 more
doaj   +2 more sources

Modulation of the Human Erythrocyte Antioxidant System by the 5- and 6-Membered Heterocycle-Based Nitroxides [PDF]

Molecules
Nitroxides are stable radicals consisting of a nitroxyl group, >N-O•, which carries an unpaired electron. This group is responsible for the paramagnetic and antioxidant properties of these compounds.
Krzysztof Gwozdzinski, Stella Bujak-Pietrek, Anna Pieniazek, Lukasz Gwozdzinski   +3 more
doaj   +2 more sources

Synthesis of tricyclic fused pyrrolidine nitroxides from 2-alkynylpyrrolidine-1-oxyls [PDF]

Beilstein Journal of Organic Chemistry
Rotational correlation time is a key parameter for organic radical contrast agents (ORCA) for magnetic resonance imaging (MRI). Design of polycyclic systems with incorporated nitroxide moieties in which rotation of the radical separately from the ...
Mark M. Gulman, Yuliya F. Polienko, Sofia Yu. Trakhininа, Yuri V. Gatilov, Tatyana V. Rybalova, Sergey A. Dobrynin, Igor A. Kirilyuk   +6 more
doaj   +2 more sources

Nitroxide-Based Contrast Agents for MRI Cancer Diagnostics: Progress, Limitations, and Perspectives [PDF]

Molecules
Magnetic resonance imaging (MRI) is one of the most powerful non-invasive methods for cancer diagnostics. To enhance image contrast and, therefore, diagnostic accuracy, contrast agents (CAs) are widely used in clinics.
Dmitry Mitin, Alexey Chubarov
doaj   +2 more sources

Rotaxane-catalyzed aerobic oxidation of primary alcohols [PDF]

Communications Chemistry
Nitroxide radicals are widely utilized as catalysts for the oxidation of primary alcohols. Here, the aerobic catalytic oxidation cycle of nitroxide radicals has been implemented within a mechanically interlocked rotaxane architecture consisting of a ...
Ilario Baù, Cecilia Poderi, Francesca Sardu, Alessia Giancola, Anna Turchetti, Paola Franchi, Lorenzo Casimiro, Leonardo Andreoni, Serena Silvi, Elisabetta Mezzina, Marco Lucarini   +10 more
doaj   +2 more sources

Towards Metabolic Organic Radical Contrast Agents (mORCAs) for Magnetic Resonance Imaging [PDF]

Molecules
We report two conjugates of gem-diethyl pyrroline nitroxide radicals with D-mannosamine as potential metabolic organic radical contrast agents, mORCAs, circumventing the need for biorthogonal reactions.
Shuyang Zhang, Sabina Dhakal, Evan Curtis, Hunter Miller, Joseph T. Paletta, Connor Gee, Suchada Rajca, Forrest Kievit, Andrzej Rajca   +8 more
doaj   +2 more sources

2-Imidazoline Nitroxide Derivatives of Cymantrene

Molecules, 2022
The 2-imidazoline nitroxide derivatives of cymantrene—2-(η5-cyclopentadienyl)tricarbonylmanganese(I)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl (NNMn) and 2-(η5-cyclopentadienyl)tricarbonylmanganese(I)-4,4,5,5-tetramethyl-4,5-dihydro-1H ...
Kseniya Maryunina, Gleb Letyagin, Galina Romanenko, Artem Bogomyakov, Vitaly Morozov, Sergey Tumanov, Sergey Veber, Matvey Fedin, Evgeniya Saverina, Mikhail Syroeshkin, Mikhail Egorov, Victor Ovcharenko   +11 more
doaj   +1 more source

The Protective Effects of Silk Sericin Against Retinal Oxidative Stress: <i>In Vitro</i> and <i>In Vivo</i> Assays with a Fluorometric Nitroxide Molecular Probe. [PDF]

Molecules
Rayner CL, Suzuki S, Chirila TV, Barnett NL.   +3 more
europepmc   +2 more sources

Fluorinated Organic Paramagnetic Building Blocks for Cross-Coupling Reactions

Molecules, 2020
New stable polyfluorinated nitroxide radicals for use in cross-coupling reactions, namely, N-tert-butyl-N-oxyamino-2,3,5,6-tetrafluoro-4-iodobenzene and N-tert-butyl-N-oxyamino-2,3,5,6-tetrafluoro-4-ethynylbenzene, were prepared from perfluoroiodobenzene.
Larisa V. Politanskaya, Pavel A. Fedyushin, Tatyana V. Rybalova, Artem S. Bogomyakov, Nargiz B. Asanbaeva, Evgeny V. Tretyakov   +5 more
doaj   +1 more source

Inhibition of metastatic brain cancer in Sonic Hedgehog medulloblastoma using caged nitric oxide albumin nanoparticles

Frontiers in Oncology, 2023
Medulloblastoma is a tumor of the cerebellum that metastasizes to the leptomeninges of the central nervous system (CNS), including to forebrain and to spinal cord.
Bohdan J. Soltys, Katie B. Grausam, Shanta M. Messerli, Carleton J. C. Hsia, Haotian Zhao, Haotian Zhao, Haotian Zhao   +6 more
doaj   +1 more source