Results 31 to 40 of about 14,461 (232)

Synthesis and Evaluation of Ciprofloxacin-Nitroxide Conjugates as Anti-Biofilm Agents

Molecules, 2016
As bacterial biofilms are often refractory to conventional antimicrobials, the need for alternative and/or novel strategies for the treatment of biofilm related infections has become of paramount importance.
Anthony D. Verderosa, Sarah C. Mansour, César de la Fuente-Núñez, Robert E. W. Hancock, Kathryn E. Fairfull-Smith   +4 more
doaj   +1 more source

A New Method for the Synthesis of Heterospin Complexes

Crystals, 2015
The interaction of binuclear Co(II) pivalate [Сo2(H2O)Piv4(HPiv)4] with nitronyl nitroxide HL1 (2-(2-hydroxy-5-nitrophenyl)-4,4,5,5-tetramethyl-4,5-dihydro-1H-imidazole-3-oxide-1-oxyl) in organic solvents led to the formation of a pentanuclear heterospin
Victor Ovcharenko, Olga Kuznetsova, Elena Fursova, Gаlinа Romаnenko, Artem Bogomyakov   +4 more
doaj   +1 more source

Application of a Fluorescent Probe for the Online Measurement of PM-Bound Reactive Oxygen Species in Chamber and Ambient Studies

Sensors, 2019
This manuscript details the application of a profluorescent nitroxide (PFN) for the online quantification of radical concentrations on particulate matter (PM) using an improved Particle Into Nitroxide Quencher (PINQ). A miniature flow-through fluorimeter
Reece Brown, Svetlana Stevanovic, Zachary Brown, Mingfu Cai, Shengzhen Zhou, Wei Song, Xinming Wang, Branka Miljevic, Jun Zhao, Steven Bottle, Zoran Ristovski   +10 more
doaj   +1 more source

Studies on the antioxidative activity of red pigments in Italian-type dry-cured ham [PDF]

, 2003
Aqueous phosphate buffer extracts and acetone/water extracts of pigments from Parma ham were assessed as antioxidants by (1) electron spin resonance spectroscopy using a spin probing technique to evaluate their efficiencies as scavengers of free radicals,
Adamsen, Christina E., Hansen, Mette L., Møller, Jens K.S., Skibsted, Leif H.   +3 more
core   +1 more source

Residue‐Specific Signatures of Structural Water Identified by Dissolution Dynamic Nuclear Polarization with UV‐Generated Radicals

Angewandte Chemie, EarlyView.
Structural water molecules in proteins are notoriously hard to detect in solution. Hyperpolarized water with UV radicals as polarizing agents provides the sensitivity and resolution to detect residue‐specific signatures of structural water with NMR spectroscopy.
Fabian Hecker, Kaare Teilum, Andrea Capozzi, Mathilde Hauge Lerche   +3 more
wiley   +2 more sources

Bis(nitrato-κO)bis[4,4,5,5-tetramethyl-2-(5-methyl-1H-imidazol-4-yl-κN3)-2-imidazoline-1-oxyl 3-oxide-κO]nickel(II)

Acta Crystallographica Section E, 2011
In the centrosymmetric mononuclear title complex, [Ni(NO3)2(C11H17N4O2)2], the NiII atom displays a distorted octahedral coordination geometry and is six-coordinated by two N,O-bidentate nitronyl nitroxide radical ligands and two monodentate nitrate ...
Jiu Li Chang, Zhi Yong Gao
doaj   +1 more source

Electrochemical behavior of indolone-N-oxides: Relationship to structure and antiplasmodial activity [PDF]

, 2012
Indolone-N-oxides exert high parasiticidal activity at the nanomolar level in vitro against Plasmodiumfalciparum, the parasite responsible for malaria.
Fabre, Paul-Louis, Ibrahim, Hany, Montrose, Armelle, Nepveu, Françoise, Nguyen, Thi Hoang Yen, Perio, Pierre, Reybier, Karine   +6 more
core   +3 more sources

Simultaneous Imaging of Cu+ and Cu2+ in Neural Cells Using DNAzyme Probes Reveals Mechanistic Link Between Copper Redox Imbalance and Amyloid Pathology

Angewandte Chemie, EarlyView.
We develop Cu+‐ and Cu2+‐specific DNAzyme fluorescent probes to visualize both copper redox states in living neurons. Aβ oligomers cause intracellular copper overload, triggering FDX1 dependent cuproptosis and generating ROS. This work links copper redox imbalance with Aβ pathology and offers a selective, sensitive way to monitor copper homeostasis in ...
Xiangli Shao, Zhenglin Yang, Zhihao Xu, Weijie Guo, Whitney Lewis, Boyi Gan, Yi Lu   +6 more
wiley   +2 more sources

A Crystallographic Study of a Novel Tetrazolyl-Substituted Nitronyl Nitroxide Radical

Crystals, 2018
Spin-labelled compounds are widely used in chemistry, physics, biology, and material sciences, but the directed synthesis of some functionalized organic radicals is still a challenge.
Vasily E. Romanov, Irina Yu. Bagryanskaya, Dmitry E. Gorbunov, Nina P. Gritsan, Elena V. Zaytseva, Dominique Luneau, Evgeny V. Tretyakov   +6 more
doaj   +1 more source

Computational study of radicals derived from hydroxyurea and its methylated analogues. [PDF]

, 2012
Structural and electronic properties and chemical fate of free radicals generated from hydroxyurea (HU) and its methylated analogues N-methylhydroxyurea (NMHU) and O-methylhydroxyurea (OMHU) are of utmost importance for their biological and ...
Birus, Mladen, Sakic, Davor, Vinkovic Vrcek, Ivana, Vrcek, Valerije, Zipse, Hendrik   +4 more
core   +1 more source