Results 51 to 60 of about 57,017 (303)

Switching disease‐modifying therapies in patients with spinal muscular atrophy: A systematic review on effectiveness outcomes

British Journal of Clinical Pharmacology, EarlyView.
With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić, Elvira Meni Maria Gkrinia, Patrick Eustaquio, Andrea Katrin Faour, Dinko Vitezić   +4 more
wiley   +1 more source

The Association Between Perpetration of Relational Aggressive Tendencies and Adolescent Antisocial Behavior

Behavioral Sciences &the Law, EarlyView.
ABSTRACT Most research on relational aggression has primarily examined these behaviors among children, with limited exploration of its developmental progression during early adolescence and its associations with antisocial behaviors such as alcohol use, physical aggression, and rule‐breaking conduct.
Briana Amador, Timothy Lawrence, Qiyue Zhang, Ariel McField, Lily Palmer, Oi‐Man Kwok   +5 more
wiley   +1 more source

Non-invasive positive pressure ventilation in children

Journal of Pediatric Critical Care, 2018
Respiratory problems are common in pediatric population and need advanced respiratory support in intensive care for various reasons. Mechanical ventilation is most important mode of therapy/support of modern era in intensive care units.
Kundan Mittal, N Rungta, Vinayak Patki, H K Aggarwal   +3 more
doaj   +1 more source

An Epidemiological Analysis of SARS-CoV-2 Genomic Sequences from Different Regions of India

Viruses, 2021
The number of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) cases is increasing in India. This study looks upon the geographic distribution of the virus clades and variants circulating in different parts of India between January and August
Pragya D. Yadav, Dimpal A. Nyayanit, Triparna Majumdar, Savita Patil, Harmanmeet Kaur, Nivedita Gupta, Anita M. Shete, Priyanka Pandit, Abhinendra Kumar, Neeraj Aggarwal, Jitendra Narayan, Neetu Vijay, Usha Kalawat, Attayur P. Sugunan, Ashok Munivenkatappa, Tara Sharma, Sulochna Devi, Tapan Majumdar, Subhash Jaryal, Rupinder Bakshi, Yash Joshi, Rima Sahay, Jayanti Shastri, Mini Singh, Manoj Kumar, Vinita Rawat, Shanta Dutta, Sarita Yadav, Kaveri Krishnasamy, Sharmila Raut, Debasis Biswas, Biswajyoti Borkakoty, Santwana Verma, Sudha Rani, Hirawati Deval, Disha Patel, Jyotirmayee Turuk, Bharti Malhotra, Bashir Fomda, Vijaylakshmi Nag, Amita Jain, Anudita Bhargava, Varsha Potdar, Sarah Cherian, Priya Abraham, Anjani Gopal, Samiran Panda, Balram Bhargava   +47 more
doaj   +1 more source

Proposed regulation of NiV-F neuronal sorting by NiV-G.

, 2014
NiV-F (F0 inactive precursor) and NiV-G (G) exhibit relatively fast and slow biosynthetic trafficking, respectively (full and dashed lines in scheme). In the absence of G, F0 is first sorted to the somatodendritic plasma membrane and then internalized to
Gonzalo A. Mardones (500143), Rafael Mattera (564920), Juan S. Bonifacino (249633), Ginny G. Farías (564921)   +3 more
core   +1 more source

The Incidence, Severity and Clinical Consequence of Left Pulmonary Artery Stenosis After PDA Device Closure in Premature Infants Less Than 2 Kilograms

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Transcatheter patent ductus arteriosus (PDA) device closure is an effective treatment option for premature infants with hemodynamically significant PDA. Left pulmonary artery (LPA) stenosis has been reported as a complication, however there is limited data on risk factors, clinical significance, and long‐term outcomes.
Bryan Mosher, Robin Wolschendorf, Preston Boyer, Jimmy C. Lu, Ray Lowery, Sunkyung Yu, Ashley Duimstra, Jeffrey D. Zampi   +7 more
wiley   +1 more source

Long-term non-invasive ventilation for stable chronic hypercapnic COPD

European Clinical Respiratory Journal, 2019
Introduction: Long-term non-invasive ventilation (LTNIV) for the stable hypercapnic chronic obstructive pulmonary disease (COPD)-patients have been a subject of much debate in the last two decades.
Eline K. Gantzhorn, Thomas Skovhus Prior, Ole Hilberg   +2 more
doaj   +1 more source

Comparison of NIV-NAVA and NCPAP in facilitating extubation for very preterm infants

BMC Pediatrics, 2019
BackgroundVarious types of noninvasive respiratory modalities that lead to successful extubation in preterm infants have been explored. We aimed to compare noninvasive neurally adjusted ventilatory assist (NIV-NAVA) and nasal continuous positive airway ...
B. Lee, Seung-Han Shin, Y. Jung, E. Kim, Han-Suk Kim   +4 more
semanticscholar   +1 more source

Interaction with NiV-G abolishes somatodendritic sorting of NiV-F.

, 2014
(A) Co-immunoprecipitation of NiV-F and NiV-G. HEK293T cells were co-transfected with NiV-F-GFP and NiV-G-HA; approximately 24–27 h post-transfection, cells were lysed and subjected to immunoprecipitation (IP) with rabbit anti-HA.
Gonzalo A. Mardones (500143), Rafael Mattera (564920), Juan S. Bonifacino (249633), Ginny G. Farías (564921)   +3 more
core   +1 more source

Volume Targeted Algorithms. Are they a one-size-fits-all approach to noninvasive ventilation?

Journal of Mechanical Ventilation
Noninvasive ventilation (NIV) has rapidly expanded as the principle respiratory support strategy in a variety of disease states ultimately resulting in respiratory insufficiency including COPD, overlap syndrome (COPD + comingled sleep disordered ...
David Troxell
doaj   +1 more source