Results 41 to 50 of about 35,271 (262)
Elicitation of immune responses against Nipah virus by an engineered synthetic DNA vaccine
Frontiers in Virology, 2022 Nipah virus (NiV) is a re-emerging pathogen that causes severe disease in animals and humans. Current treatment measures for NiV infection are insufficient, and there is no approved vaccine against NiV for either humans or animals.
Hyeree Choi +8 more
doaj +1 more source
Loss of O-glycans in NiV G does not affect NiV F incorporation in pseudotyped virions, but affects NiV F processing and pseudotyped viral entry. [PDF]
, 2016 A) Western blot of NiV/VSV viral lysates. NiV G (top panel) and NiV F (bottom panel) were detected as described in Fig 2. B) F incorporation and F processing of the NiV mutant pseudotyped virions determined by densitometry.
Jacquelyn A. Stone (488032) +3 more
core +1 more source
Co-assembly of viral envelope glycoproteins regulates their polarized sorting in neurons. [PDF]
PLoS Pathogens, 2014 Newly synthesized envelope glycoproteins of neuroinvasive viruses can be sorted in a polarized manner to the somatodendritic and/or axonal domains of neurons.
Rafael Mattera +3 more
doaj +1 more source
Advanced Materials Technologies, EarlyView.This review systematically explains the synthesis, properties, and energy storage and conversion applications of vanadium carbides. We introduce the structural and the synthetic strategies and reviewed recent developments in the material synthesis processes. The emerging applications of vanadium carbides in energy storage and conversion are highlighted.
Swathy B. Saseendran +2 more
wiley +1 more source
Advanced Science, EarlyView.The cysteine redox state of the Hendra virus W (WHeV) protein controls assembly into fibrils or amorphous aggregates, with residues 2–29 required for fibrillation. In cells, WHeV forms different types of nuclear condensates. Impaired ability to form redox‐sensitive, non‐filamentous condensates reduces WHeV inhibition of the NF‐κB pathway, while it ...
Frank Gondelaud +12 more
wiley +1 more source
Establishment of Humanized EFNB2/B3 Murine Models for Investigating Nipah Virus Pathogenesis
Animal Research and One Health, EarlyView.ABSTRACT Nipah virus (NiV) is a zoonotic paramyxovirus classified as a WHO priority pathogen, which causes severe respiratory disease and encephalitis in humans with high mortality. Currently, no licensed vaccines or specific antiviral therapies are available.
Wei Dong +6 more
wiley +1 more source
Non-invasive positive pressure ventilation in children
Journal of Pediatric Critical Care, 2018 Respiratory problems are common in pediatric population and need advanced respiratory support in intensive care for various reasons. Mechanical ventilation is most important mode of therapy/support of modern era in intensive care units.
Kundan Mittal +3 more
doaj +1 more source
Clinical signs and outcome of hamsters inoculated with NiV-M or NiV-B. [PDF]
, 2013 aExcluding survivors.bSignificant difference between NiV-M and NiV-B at dose 103 TCID50 ...
Joseph Prescott (102362) +5 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić +4 more
wiley +1 more source
Long-term non-invasive ventilation for stable chronic hypercapnic COPD
European Clinical Respiratory Journal, 2019 Introduction: Long-term non-invasive ventilation (LTNIV) for the stable hypercapnic chronic obstructive pulmonary disease (COPD)-patients have been a subject of much debate in the last two decades.
Eline K. Gantzhorn +2 more
doaj +1 more source