Results 31 to 40 of about 57,017 (303)

Computational Identification of Potential Multitarget Inhibitors of Nipah Virus by Molecular Docking and Molecular Dynamics

open access: yesMicroorganisms, 2022
Nipah virus (NiV) is a recently emerged paramyxovirus that causes severe encephalitis and respiratory diseases in humans. Despite the severe pathogenicity of this virus and its pandemic potential, not even a single type of molecular therapeutics has been
Vinay Randhawa   +2 more
doaj   +1 more source

NiV-C interacts with NiV-M to promote budding.

open access: yes, 2016
(A) NiV-C-HA and NiV-M were transfected as indicated in 293T cells, and lysates were immunoprecipitated with anti-NiV-M as described in Materials and Methods. NiV-C was detected with anti-HA.
Tatyana Yun (404063)   +8 more
core   +1 more source

“Comparison between high-flow nasal cannula (HFNC) therapy and noninvasive ventilation (NIV) in children with acute respiratory failure by bronchiolitis: a randomized controlled trial”

open access: yesBMC Pediatrics
The objective of this study was to compare HFNC therapy to noninvasive ventilation (NIV/BiPAP) in children with bronchiolitis who developed respiratory failure. We hypothesized that HFNC therapy would not be inferior to NIV.
A. C. E. Z. Santos   +7 more
semanticscholar   +1 more source

NiV-M and NiV-B genome:Particle:PFU ratio.

open access: yes, 2018
NiV-M and NiV-B genome:Particle:PFU ratio.
Kenneth S. Jensen (5420984)   +5 more
core   +1 more source

NiV-M targets TRIM6 for degradation during NiV infection.

open access: yes, 2016
A) HeLa cells were infected with NiV-WT or NiV lacking the matrix protein (NiV-ΔM), expressing GFP, at MOI of 0.1. Forty-eight hours p.i.
Preeti Bharaj (30274)   +9 more
core   +1 more source

NiV-M budding is enhanced by NiV-C in an ESCRT-dependent manner.

open access: yes, 2016
(A) A schematic of the NiV genome is shown, with the NiV genes arrayed between the genomic termini, the 3’ leader (3’le) and 5’ trailer (5’tr). NiV-V and -W are produced by the stochastic inclusion of additional G nucleotides in the P mRNA via polymerase
Tatyana Yun (404063)   +8 more
core   +1 more source

Microencapsulation of engineered bacteria towards whole-cell-based environmental biosensing

open access: yesFrontiers in Bioengineering and Biotechnology
IntroductionLegitimate concerns about the quality of environmental waters are on the rise. As a consequence, efforts are being made by both the scientific community and policymakers to develop proficient methods for the monitoring and detection of ...
Luana Cuvillier, Guillaume Nonglaton
doaj   +1 more source

NiV-M interacts with TRIM6 and inhibits TRIM6-medited IFNβ induction and signaling.

open access: yes, 2016
A) NiV-M interacts with TRIM6. HEK293T cells were transfected with NiV-M, empty vector or HA-TRIM6. Cells were harvested and whole cell extracts (WCE) were used for TRIM6 immunoprecipitation using anti-HA-beads.
Preeti Bharaj (30274)   +9 more
core   +1 more source

Comparative pathogenicity study of monkeypox virus Clade Ib and Clade IIb in a rabbit model

open access: yesVirulence
Mpox has emerged as a significant public health concern, spreading across continents with the emergence of new variants. Clade IIb, from the recent global outbreak, and the newly identified Clade Ib have shown changes in transmission dynamics and ...
Sreelekshmy Mohandas   +6 more
doaj   +1 more source

Elicitation of immune responses against Nipah virus by an engineered synthetic DNA vaccine

open access: yesFrontiers in Virology, 2022
Nipah virus (NiV) is a re-emerging pathogen that causes severe disease in animals and humans. Current treatment measures for NiV infection are insufficient, and there is no approved vaccine against NiV for either humans or animals.
Hyeree Choi   +8 more
doaj   +1 more source

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