Results 31 to 40 of about 4,243,571 (286)

Molecular Evolution of the NLR Gene Family Reveals Diverse Innate Immune Strategies in Bats [PDF]

open access: yesBiomolecules
Bats, as the world’s second-largest mammalian order, have garnered significant attention for their ability to harbor numerous viruses without exhibiting disease symptoms.
Gang Liu   +10 more
doaj   +2 more sources

Genome-Wide Identification and Functional Evolution of NLR Gene Family in Capsicum annuum

open access: yesCurrent Issues in Molecular Biology
Capsicum annuum (pepper) is a globally significant Solanaceous crop vulnerable to devastating pathogens such as Phytophthora capsici. Nucleotide-binding leucine-rich repeat (NLRs) proteins are crucial intracellular immune receptors mediating effector ...
Chong Feng   +4 more
doaj   +3 more sources

Correlation of neutrophil/lymphocyte, monocyte/lymphocyte, and CRP/ALB ratios with the extent of coronary artery lesions and their predictive value [PDF]

open access: yesFrontiers in Cardiovascular Medicine
ObjectiveThe aim of this paper was to investigate the correlation between neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), and CRP/ALB ratios with the degree of coronary artery disease and their predictive value.MethodsThis study retrospectively ...
Mingming Zhao   +3 more
doaj   +2 more sources

Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Few studies have investigated the mechanism by which exercise training promotes neural repair during rehabilitation after stroke. In this study, we evaluated the neuroprotective effects of exercise training and pyroptosis-associated factors
Fang Luo   +5 more
doaj   +1 more source

Editorial: The role of nod-like receptor (NLR) family of proteins in inflammation [PDF]

open access: yesFrontiers in Immunology
Atika Dhar   +3 more
doaj   +2 more sources

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis

open access: yesJournal of Innate Immunity, 2023
PR domain-containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis.
Qingsong Zhao   +6 more
doaj   +1 more source

The NLR Gene Family: A Standard Nomenclature [PDF]

open access: yesImmunity, 2008
Iimmune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, cryopyrin/NALP3 are members of a family characterized by the presence of a nucleotide-binding domain (NBD) and leucine-rich repeats (LRR). Members of this gene family encode a protein structure similar to the NB-LRR subgroup of disease-resistance genes in plants and are involved ...
Ting, Jenny P.-Y.   +23 more
openaire   +4 more sources

NLR family pyrin domain containing 3 (NLRP3) and caspase 1 (CASP1) modulation by intracellular Cl– concentration

open access: yesImmunology, 2021
The impairment of the cystic fibrosis transmembrane conductance regulator (CFTR) activity induces intracellular chloride (Cl–) accumulation. The anion Cl–, acting as a second messenger, stimulates the secretion of interleukin‐1β (IL‐1β), which starts an ...
Mariángeles Clauzure   +9 more
semanticscholar   +1 more source

Genome-wide identification of nucleotide-binding domain leucine-rich repeat (NLR) genes and their association with green peach aphid (Myzus persicae) resistance in peach

open access: yesBMC Plant Biology, 2023
Resistance genes (R genes) are a class of genes that are immune to a wide range of diseases and pests. In planta, NLR genes are essential components of the innate immune system.
Haixiang Yu   +8 more
doaj   +1 more source

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