Results 31 to 40 of about 90,508 (248)

NLRC4/IPAF: a CARD carrying member of the NLR family [PDF]

open access: yesClinical Immunology, 2009
The NOD-like receptor (NLR) family of proteins is involved in the regulation of innate immune responses and cell death pathways. Recent findings show that the NLR family member NLRC4 (also known as IPAF) has important roles in innate immune responses to Gram-negative bacteria.
Fayyaz S, Sutterwala, Richard A, Flavell
openaire   +2 more sources

Predictive Value of Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Immediate Outcomes of ST-elevation Myocardial Infarction: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: There have been various inflammatory markers implicated in the pathogenesis of Acute Coronary Syndromes (ACS). However, the role of the Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as prognostic markers in ST ...
Sneha Barkur sadashiva, KS Chenthil
doaj   +1 more source

Comparative-genomic analysis reveals dynamic NLR gene loss and gain across Apiaceae species

open access: yesFrontiers in Genetics, 2023
Introduction: Nucleotide-binding leucine-rich repeat (NLR) genes play a crucial role in green plants’ responding to various pathogens. Genome-scale evolutionary studies of NLR genes are important for discovering and applying functional NLR genes. However,
Xiaohui Liang, Junming Dong
doaj   +1 more source

Phylogenetic Analyses and Transcriptional Survey Reveal the Characteristics, Evolution, and Expression Profile of NBS-Type Resistance Genes in Papaya

open access: yesAgronomy, 2023
Carica papaya maintains an abnormally small but complete NLR family while showing weak disease resistance. To better understand their origin, evolution, and biological function, we identified 59 NLR genes via a customized RGAugury and investigated their ...
Qian Jiang   +8 more
doaj   +1 more source

Dancing with the Stars: An Asterid NLR Family

open access: yesTrends in Plant Science, 2017
Wu and co-workers show how a network of sensor and helper NOD-like receptor proteins (NLRs) act together to confer robust resistance to diverse plant pathogens.
Rathjen, John, Dodds, Peter
openaire   +4 more sources

PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB–p65/NLRP3 pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Asthma is a complex inflammatory disease of the lungs marked by increased infiltration of leukocytes into the airways, which restricts respiratory function.
Rui Fang   +4 more
doaj   +1 more source

NLRC4 (NLR Family, CARD domain containing 4) [PDF]

open access: yesAtlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on NLRC4 (NLR Family, CARD domain containing 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Y Kumar, V Radha, G Swarup
openaire   +1 more source

Association between neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and diabetic retinopathy among diabetic patients without a related family history

open access: yesDiabetology & Metabolic Syndrome, 2020
Background Diabetic retinopathy (DR) is a specific neurovascular complication of diabetes mellitus (DM). Clinically, family history is a widely recognized risk factor for DR, assisting diagnosis and risk strata.
Jin-Rui Wang   +12 more
doaj   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

Frequent Gene Duplication/Loss Shapes Distinct Evolutionary Patterns of NLR Genes in Arecaceae Species

open access: yesHorticulturae, 2021
Nucleotide-binding leucine-rich repeat (NLR) genes play a key role in plant immune responses and have co-evolved with pathogens since the origin of green plants.
Xiao-Tong Li   +5 more
doaj   +1 more source

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