NLR network mediates immunity to diverse plant pathogens [PDF]
Both plants and animals rely on nucleotide-binding domain and leucine-rich repeat-containing (NLR) proteins to respond to invading pathogens and activate immune responses. An emerging concept of NLR function is that “sensor” NLR proteins are paired with “
Ahmed Abd-El-Haliem +12 more
core +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Genomic evidence for genes encoding leucine-rich repeat receptors linked to resistance against the eukaryotic extra- and intracellular Brassica napus pathogens Leptosphaeria maculans and Plasmodiophora brassicae [PDF]
© 2018 Stotz et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Fitt, Bruce +7 more
core +3 more sources
Wheat Disease Resistance Genes and Their Diversification Through Integrated Domain Fusions
Plants are in a constant evolutionary arms race with their pathogens. At the molecular level, the plant nucleotide-binding leucine-rich repeat receptors (NLRs) family has coevolved with rapidly evolving pathogen effectors.
Ethan J. Andersen +7 more
doaj +1 more source
Nlrp6 promotes recovery after peripheral nerve injury independently of inflammasomes [PDF]
Background: NOD-like receptors (Nlrs) are key regulators of immune responses during infection and autoimmunity. A subset of Nlrs assembles inflammasomes, molecular platforms that are activated in response to endogenous danger and microbial ligands and ...
De Winter, Vicky +6 more
core +2 more sources
Neutrophil Lymphocyte Ratio (NLR) in COVID-19 Patients Receiving Convalescent Plasma Therapy
Recently, a new RNA virus from the Coronaviridae family was discovered, known as SARS-Cov-2. This virus causes pneumonia and inflammation in the body.
Desyani Ariza +2 more
doaj +1 more source
The NLR family pyrin domain‐containing 3 (NLRP3) inflammasome plays an important role in liver fibrosis (LF) development. However, the mechanisms involved in NLRP3‐induced fibrosis are unclear.
M. Inzaugarat +9 more
semanticscholar +1 more source
Dust in active nuclei. II. Powder or gravel? [PDF]
In a companion paper, Maiolino et al. (2000) presented various observational evidences for "anomalous" dust properties in the circumnuclear region of AGNs and, in particular, the reduced E(B-V)/N_H and Av/N_H ratios, the absence of the silicate ...
Maiolino, R., Marconi, A., Oliva, E.
core +2 more sources
The Hippo pathway, an evolutionarily conserved protein kinase cascade, tightly regulates cell growth and survival. Activation of yes‐associated protein (YAP), a downstream effector of the Hippo pathway, has been shown to modulate tissue inflammation ...
Changyong Li +9 more
semanticscholar +1 more source
Infrared spectroscopy of NGC 1068: Probing the obscured ionizing AGN continuum [PDF]
The ISO-SWS 2.5-45 um infrared spectroscopic observations of the nucleus of the Seyfert 2 galaxy NGC 1068 (see companion paper) are combined with a compilation of UV to IR narrow emission line data to determine the spectral energy distribution (SED) of ...
Amiel Sternberg +51 more
core +5 more sources

