Results 61 to 70 of about 87,795 (274)

Early Pregnancy Modulates Expression of the Nod-like Receptor Family in Lymph Nodes of Ewes

Animals, 2022
NOD receptors (NLRs) mediate adaptive immune responses and immune tolerance. Nevertheless, it is not clear if gestation modulates the NLR signaling pathway in lymph nodes of ewes. In this study, lymph nodes of ewes were collected at day 16 of the estrous
Zhenyang Zhao, Yuanjing Li, Jianhua Cao, Hongxu Fang, Leying Zhang, Ling Yang   +5 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Clinical significance and correlation of microRNA-21 expression and the neutrophil-lymphocyte ratio in patients with acute myocardial infarction [PDF]

Clinics, 2019
OBJECTIVES: To explore the clinical significance and correlation of microRNA-21 (miR-21) and the neutrophil-lymphocyte ratio (NLR) in patients with acute myocardial infarction (AMI).
Changkui Gao, Dan Zhao, Jingjing Wang, Ping Liu, Baohe Xu   +4 more
doaj   +2 more sources

NLRC5: A Potential Target for Central Nervous System Disorders

Frontiers in Immunology, 2021
Nucleotide oligomerization domain-like receptors (NLRs), a class of pattern recognition receptors, participate in the host’s first line of defense against invading pathogenic microorganisms.
Lu Zhang, Lu Zhang, Cui Jiao, Cui Jiao, Lingjuan Liu, Lingjuan Liu, Aiping Wang, Aiping Wang, Li Tang, Li Tang, Yi Ren, Yi Ren, Peng Huang, Peng Huang, Jie Xu, Jie Xu, Dingan Mao, Dingan Mao, Liqun Liu, Liqun Liu   +19 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Clinical, Histologic, and Serological Predictors of Renal Function Loss in Lupus Nephritis

Arthritis Care &Research, EarlyView.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M. Guthridge, Carla Guthridge, Peter Izmirly, Jill P. Buyon, H. Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'Era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (RA/SLE) Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

Communications Biology, 2022
This review discusses emerging roles for the NLR family pyrin domain containing 6 receptor (NLRP6) in intestinal homeostasis, inflammation, cancer, the nervous system and liver disease.
Diego Angosto-Bazarra, Cristina Molina-López, Pablo Pelegrín   +2 more
doaj   +1 more source

NLR-B30.2 online supplement

, 2015
Online supplementary material for manuscript on the evolutionary history of the NLR-B30.2 gene family in zebrafish.
Philipp Schiffer (99040)
core   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

The NLR-Annotator tool enables annotation of the intracellular immune receptor repertoire [PDF]

, 2019
Disease resistance genes encoding nucleotide-binding and leucine-rich repeat (NLR) intracellular immune receptor proteins detect pathogens by the presence of pathogen effectors. Plant genomes typically contain hundreds of NLR-encoding genes.
Ramirez-Gonzalez, Ricardo H., Wulff, Brande B, Keller, Beat, Krattinger, Simon G., Baggs, Erin, Ridout, Christopher James, Schoonbeek, Henk-jan, Witek, Agnieszka, Jones, Jonathan D, Witek, Kamil, Yu, Guotai, Krasileva, Ksenia V, Yadav, Inderjit, Steuernagel, Burkhard, Uauy, Cristobal   +14 more
core   +2 more sources