Results 41 to 50 of about 4,243,571 (286)

Predictive Value of Neutrophil Lymphocyte Ratio and Platelet Lymphocyte Ratio in Immediate Outcomes of ST-elevation Myocardial Infarction: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2021
Introduction: There have been various inflammatory markers implicated in the pathogenesis of Acute Coronary Syndromes (ACS). However, the role of the Neutrophil Lymphocyte Ratio (NLR) and Platelet Lymphocyte Ratio (PLR) as prognostic markers in ST ...
Sneha Barkur sadashiva, KS Chenthil
doaj   +1 more source

Activation of caspase-1 is mediated by stimulation of interferon genes and NLR family pyrin domain containing 3 in monocytes of active systemic lupus erythematosus.

open access: yesClinical and Experimental Rheumatology, 2021
OBJECTIVES Emerging evidence has shown the importance of inflammasome activation in the progression of autoimmune diseases. In this study, we aimed to identify the main cell types activating inflammasome in autoimmune diseases and to clarify the ...
S. Inokuchi   +9 more
semanticscholar   +1 more source

Regulation of intestinal microbiota by the NLR protein family [PDF]

open access: yesInternational Immunology, 2013
Abstract The human intestine harbors a diverse microbial community consisting of a large number of bacteria and other micro-organisms that have co-evolved with the host intestinal immune system. During this process, microbiota and the host immune system shape one another by various mechanisms to achieve a successful symbiotic ...
Amlan, Biswas, Koichi S, Kobayashi
openaire   +2 more sources

Comparative-genomic analysis reveals dynamic NLR gene loss and gain across Apiaceae species

open access: yesFrontiers in Genetics, 2023
Introduction: Nucleotide-binding leucine-rich repeat (NLR) genes play a crucial role in green plants’ responding to various pathogens. Genome-scale evolutionary studies of NLR genes are important for discovering and applying functional NLR genes. However,
Xiaohui Liang, Junming Dong
doaj   +1 more source

Phylogenetic Analyses and Transcriptional Survey Reveal the Characteristics, Evolution, and Expression Profile of NBS-Type Resistance Genes in Papaya

open access: yesAgronomy, 2023
Carica papaya maintains an abnormally small but complete NLR family while showing weak disease resistance. To better understand their origin, evolution, and biological function, we identified 59 NLR genes via a customized RGAugury and investigated their ...
Qian Jiang   +8 more
doaj   +1 more source

Comparative analysis of plant immune receptor architectures uncovers host proteins likely targeted by pathogens. [PDF]

open access: yes, 2016
BACKGROUND: Plants deploy immune receptors to detect pathogen-derived molecules and initiate defense responses. Intracellular plant immune receptors called nucleotide-binding leucine-rich repeat (NLR) proteins contain a central nucleotide-binding (NB ...
Cevik, Volkan   +4 more
core   +11 more sources

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

open access: yesHepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong   +9 more
wiley   +1 more source

PGC-1α agonist ZLN005 ameliorates OVA-induced asthma in BALB/c mice through modulating the NF-κB–p65/NLRP3 pathway [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Asthma is a complex inflammatory disease of the lungs marked by increased infiltration of leukocytes into the airways, which restricts respiratory function.
Rui Fang   +4 more
doaj   +1 more source

Association between neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and diabetic retinopathy among diabetic patients without a related family history

open access: yesDiabetology & Metabolic Syndrome, 2020
Background Diabetic retinopathy (DR) is a specific neurovascular complication of diabetes mellitus (DM). Clinically, family history is a widely recognized risk factor for DR, assisting diagnosis and risk strata.
Jin-Rui Wang   +12 more
doaj   +1 more source

Frequent Gene Duplication/Loss Shapes Distinct Evolutionary Patterns of NLR Genes in Arecaceae Species

open access: yesHorticulturae, 2021
Nucleotide-binding leucine-rich repeat (NLR) genes play a key role in plant immune responses and have co-evolved with pathogens since the origin of green plants.
Xiao-Tong Li   +5 more
doaj   +1 more source

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