Results 21 to 30 of about 90,508 (248)

Pan-NLR gene family analyses decipher evolutionary dynamics, population diversity, and potential disease resistance genes in cucumber

BMC Plant Biology
Background Cucumber (Cucumis sativus L.) is a globally important crop, yet its production is severely hampered by pathogen attacks, leading to substantial economic losses. Nucleotide-binding site-leucine-rich repeat (NLR) genes are critical components of
Baohui Zhang, Ying Deng
doaj   +2 more sources

Molecular Evolution of the NLR Gene Family Reveals Diverse Innate Immune Strategies in Bats

Biomolecules
Bats, as the world’s second-largest mammalian order, have garnered significant attention for their ability to harbor numerous viruses without exhibiting disease symptoms.
Gang Liu, Fujie Han, Xinya Guo, Liya Yang, Nishan Du, Xue Zhao, Chen Zhang, Jie Peng, Kangkang Zhang, Jiang Feng, Ying Liu   +10 more
doaj   +3 more sources

Imperatorin alleviated NLR family pyrin domain-containing 3 inflammasome cascade-induced synovial fibrosis and synovitis in rats with knee osteoarthritis [PDF]

Bioengineered, 2021
Haosheng Zhang, Pei-Min Wang, Zhengquan Huang   +2 more
exaly   +2 more sources

Corrigendum: Genetic Variations of NLR family genes in Behcet's Disease. [PDF]

Sci Rep, 2016
Scientific Reports 6: Article number: 20098; published online: 01 February 2016; updated: 31 May 2016 This Article contains errors. In Table 1, the number of Female ‘186’ and Male ‘764’ patients enrolled in this study is incorrectly given as ‘950’ and ‘755’ respectively.
Li L, Yu H, Jiang Y, Deng B, Bai L, Kijlstra A, Yang P.   +6 more
europepmc   +4 more sources

Genome-Wide Identification and Functional Evolution of NLR Gene Family in Capsicum annuum

Current Issues in Molecular Biology
Capsicum annuum (pepper) is a globally significant Solanaceous crop vulnerable to devastating pathogens such as Phytophthora capsici. Nucleotide-binding leucine-rich repeat (NLRs) proteins are crucial intracellular immune receptors mediating effector ...
Chong Feng, Qi Chen, Wenhao Liu, Tengfei Li, Tuo Ji   +4 more
doaj   +3 more sources

Treadmill training attenuates pyroptosis in rats with cerebral ischemia/reperfusion injury [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Few studies have investigated the mechanism by which exercise training promotes neural repair during rehabilitation after stroke. In this study, we evaluated the neuroprotective effects of exercise training and pyroptosis-associated factors
Fang Luo, Mingjin Zhu, Kunkun Lv, Di Sun, Guifen Yang, Guoyuan Pan   +5 more
doaj   +1 more source

Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis

Journal of Innate Immunity, 2023
PR domain-containing 1 with zinc finger domain (PRDM1) has been reported as a promoter of inflammation, which is a critical process involved in the pathogenesis of acute gouty arthritis.
Qingsong Zhao, Nan Xia, Jinmei Xu, Yingnan Wang, Luwen Feng, Dihan Su, Zhifeng Cheng   +6 more
doaj   +1 more source

The NLR Gene Family: A Standard Nomenclature [PDF]

Immunity, 2008
Iimmune regulatory proteins such as CIITA, NAIP, IPAF, NOD1, NOD2, NALP1, cryopyrin/NALP3 are members of a family characterized by the presence of a nucleotide-binding domain (NBD) and leucine-rich repeats (LRR). Members of this gene family encode a protein structure similar to the NB-LRR subgroup of disease-resistance genes in plants and are involved ...
Ting, Jenny P.-Y., Lovering, Ruth C., Alnemri, Emad S., Bertin, John, Boss, Jeremy M., Davis, Beckley K., Flavell, Richard A., Girardin, Stephen E., Godzik, Adam, Harton, Jonathan A., Hoffman, Hal M., Hugot, Jean-Pierre, Inohara, Naohiro, Mackenzie, Alex, Maltais, Lois J., Nunez, Gabriel, Ogura, Yasunori, Otten, Luc A., Philpott, Dana, Reed, John C., Reith, Walter, Schreiber, Stefan, Steimle, Viktor, Ward, Peter A.   +23 more
openaire   +3 more sources

Regulation of intestinal microbiota by the NLR protein family [PDF]

International Immunology, 2013
Abstract The human intestine harbors a diverse microbial community consisting of a large number of bacteria and other micro-organisms that have co-evolved with the host intestinal immune system. During this process, microbiota and the host immune system shape one another by various mechanisms to achieve a successful symbiotic ...
Amlan, Biswas, Koichi S, Kobayashi
openaire   +2 more sources

Genome-wide identification of nucleotide-binding domain leucine-rich repeat (NLR) genes and their association with green peach aphid (Myzus persicae) resistance in peach

BMC Plant Biology, 2023
Resistance genes (R genes) are a class of genes that are immune to a wide range of diseases and pests. In planta, NLR genes are essential components of the innate immune system.
Haixiang Yu, Xuelian Wu, Jiahui Liang, Ziying Han, Yuansong Xiao, Hao Du, Yihua Liu, Jian Guo, Futian Peng   +8 more
doaj   +1 more source