Results 1 to 10 of about 87,795 (274)
Structure and evolutionary history of a large family of NLR proteins in the zebrafish [PDF]
Open Biology, 2016 Multicellular eukaryotes have evolved a range of mechanisms for immune recognition. A widespread family involved in innate immunity are the NACHT-domain and leucine-rich-repeat-containing (NLR) proteins.
Kerstin Howe +8 more
doaj +7 more sources
The Nod-like receptor (NLR) family: a tale of similarities and differences. [PDF]
PLoS ONE, 2008 Innate immunity represents an important system with a variety of vital processes at the core of many diseases. In recent years, the central role of the Nod-like receptor (NLR) protein family became increasingly appreciated in innate immune responses ...
Martina Proell +4 more
doaj +6 more sources
Genome-wide identification and analysis of the NLR gene family in Medicago ruthenica
Frontiers in Genetics, 2023 Medicago ruthenica, important forage in the legume family, possesses high nutritional value and carries abundant tolerance genes. This study used whole-genome data of M.
Chunyan Tong +5 more
doaj +5 more sources
The NLR family of innate immune and cell death sensors [PDF]
ImmunityNucleotide-binding oligomerization domain (NOD)-like receptors, also known as nucleotide-binding leucine-rich repeat receptors (NLRs), are a family of cytosolic pattern recognition receptors that detect a wide variety of pathogenic and sterile triggers. Activation of specific NLRs initiates pro- or anti-inflammatory signaling cascades and the formation
Balamurugan Sundaram +2 more
exaly +4 more sources
BMC Evolutionary Biology, 2008 Background A large multigene family of NOD-like receptor (NLR) molecules have been described in mammals and implicated in immunity and apoptosis. Little information, however, exists concerning this gene family in non-mammalian taxa.
Winton James R +3 more
doaj +4 more sources
Genetic Variations of NLR family genes in Behcet's Disease. [PDF]
Sci Rep, 2016 Abstract This study aimed to investigate whether single nucleotide polymorphisms (SNPs) of five NLR family genes (NOD1, NOD2, NLRP1, NLRP3 and CIITA) are associated with Behcet’s disease (BD) in a Chinese Han population. The study was carried out in 950 BD patients and 1440 controls for 19 SNPs in the selected NLR genes.
Li L +6 more
europepmc +5 more sources
Posttranslational Regulation of the NLR Family Pyrin Domain-Containing 3 Inflammasome [PDF]
Frontiers in Immunology, 2018 The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is a multi-protein complex that can be activated by a variety of pathogen-associated molecular patterns or damage-associated molecular patterns.
Do-Wan Shim, Kwang-Ho Lee, Kwang-Ho Lee
doaj +5 more sources
Genome-wide identification of the NLR gene family in Haynaldia villosa by SMRT-RenSeq [PDF]
BMC Genomics, 2022 Background Nucleotide-binding and leucine-rich repeat (NLR) genes have attracted wide attention due to their crucial role in protecting plants from pathogens.
Zhenpu Huang +11 more
doaj +5 more sources
NLRC4 (NLR Family, CARD domain containing 4) [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 Review on NLRC4 (NLR Family, CARD domain containing 4), with data on DNA, on the protein encoded, and where the gene is implicated.
Y Kumar, V Radha, G Swarup
openaire +2 more sources
Fine dissection of limber pine resistance to Cronartium ribicola using targeted sequencing of the NLR family [PDF]
BMC Genomics, 2021 Background Proteins with nucleotide binding site (NBS) and leucine-rich repeat (LRR) domains (NLR) make up one of most important resistance (R) families for plants to resist attacks from various pathogens and pests. The available transcriptomes of limber
Jun-Jun Liu +5 more
doaj +2 more sources