Results 1 to 10 of about 90,508 (248)

NEKfla: A Genetically Encoded Förster Resonance Energy Transfer Biosensor for Live-Cell Monitoring of Early NIMA-Related Kinase 7-NLR Family Pyrin Domain Containing 3 Inflammasome Signaling. [PDF]

Biomater Res
Ahn S, Suh JS, Jang Y, Choi G, Han K, Lee Y, Lee D, Song C, Go JM, Kim M, Lee J, Lee JH, Kim HW, Yun H, Kim TJ.   +14 more
europepmc   +1 more source

A basic function of the NLR family is control and detection of neuropeptide expression.

Quantity of gene product present in the cell is strictly held under transcriptional control. Molecules with bioactive properties, like neuropeptides involved in feeding, anxiety and social behaviors, may be guarded at the level of quantity through distinct mechanisms to prevent ensuing disease related to or based on derestricted function of the guarded
openaire   +2 more sources

miR-23a-5p Alleviates Gouty Inflammation by Targeting Interleukin-17A and Inhibiting NLR Family Pyrin Domain Containing 3 Inflammasome Activation. [PDF]

Arch Rheumatol
Yuan X, Lin C, Zhang Y, He H, Li L.
europepmc   +1 more source

Knock-down of microRNA miR-556-5p increases cisplatin-sensitivity in non-small cell lung cancer (NSCLC) via activating NLR family pyrin domain containing 3 (NLRP3)-mediated pyroptotic cell death. [PDF]

Bioengineered, 2021
Shi F, Zhang L, Liu X, Wang Y.
europepmc   +1 more source

Celastrol alleviates esophageal stricture in rats by inhibiting NLR family pyrin domain containing 3 activation. [PDF]

World J Gastroenterol
Zhang MX, Wu C, Feng XX, Tian W, Zhao NH, Lu PP, Ding Q, Liu M.   +7 more
europepmc   +1 more source

New insights into the structure domain and function of NLR family CARD domain containing 5. [PDF]

Cell Commun Signal
Zhu H, Xiao C, Chen J, Guo B, Wang W, Tang Z, Cao Y, Zhan L, Zhang JH.   +8 more
europepmc   +1 more source

Apurinic/apyrimidinic endonuclease 1/reduction-oxidation effector factor-1 (APE1) regulates the expression of NLR family pyrin domain containing 3 (NLRP3) inflammasome through modulating transcription factor NF-κB and promoting the secretion of inflammatory mediators in macrophages. [PDF]

Ann Transl Med, 2021
Tang Z, Wang Y, Wan Y, Xie Y, Li S, Tao D, Wang C, Wu YZ, Sui JD.   +8 more
europepmc   +1 more source

Peroxiredoxin 1 inhibits tumorigenesis by activating the NLR family pyrin domain containing 3/gasdermin D pathway: Advanced therapies targeting heterogeneous cell death mechanisms. [PDF]

World J Gastroenterol
Smirnova A, Eygel D, Kondrasheva I, Baranovskii DS, Klabukov ID.   +4 more
europepmc   +1 more source

PKC Delta Activation Promotes Endoplasmic Reticulum Stress (ERS) and NLR Family Pyrin Domain-Containing 3 (NLRP3) Inflammasome Activation Subsequent to Asynuclein-Induced Microglial Activation: Involvement of Thioredoxin-Interacting Protein (TXNIP)/Thioredoxin (Trx) Redoxisome Pathway. [PDF]

Front Aging Neurosci, 2021
Samidurai M, Palanisamy BN, Bargues-Carot A, Hepker M, Kondru N, Manne S, Zenitsky G, Jin H, Anantharam V, Kanthasamy AG, Kanthasamy A.   +10 more
europepmc   +1 more source

Insights into the structure of NLR family member X1: Paving the way for innovative drug discovery. [PDF]

Comput Struct Biotechnol J
Jewell S, Nguyen TB, Ascher DB, Robertson AAB.   +3 more
europepmc   +1 more source