Results 81 to 90 of about 4,243,571 (286)

NLRC5: A Potential Target for Central Nervous System Disorders

Frontiers in Immunology, 2021
Nucleotide oligomerization domain-like receptors (NLRs), a class of pattern recognition receptors, participate in the host’s first line of defense against invading pathogenic microorganisms.
Lu Zhang, Lu Zhang, Cui Jiao, Cui Jiao, Lingjuan Liu, Lingjuan Liu, Aiping Wang, Aiping Wang, Li Tang, Li Tang, Yi Ren, Yi Ren, Peng Huang, Peng Huang, Jie Xu, Jie Xu, Dingan Mao, Dingan Mao, Liqun Liu, Liqun Liu   +19 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Isolation and fine mapping of Rps6: An intermediate host resistance gene in barley to wheat stripe rust [PDF]

, 2016
A plant may be considered a nonhost of a pathogen if all known genotypes of a plant species are resistant to all known isolates of a pathogen species. However, if a small number of genotypes are susceptible to some known isolates of a pathogen species ...
AJ Castro, Amelia Hubbard, Andrew M. Dawson, B Lü, C Silvar, CN Stewart Jr, CR Wellings, D Schulte, DM Vienne de, E Potokina, FH McNeal, FK Yeo, G Backes, H Jafary, H Jafary, H Thordal-Christensen, I Nover, IBGSC, J Bettgenhaeuser, J Eriksson, John N. Ferguson, JW Ooijen van, KF Mayer, KS Mysore, L Derevnina, M Kearse, M Mascher, M Muñoz-Amatriaín, M Schönfeld, Matthew Gardiner, Matthew J. Moscou, MC Heath, MH Borhan, MJ Moscou, N Lauter, P Schulze-Lefert, P Szűcs, Phon Green, R Aghnoum, R Ariyadasa, R Brueggeman, R Kota, RE Niks, RE Niks, RH Ramirez-Gonzalez, RW Doerge, RW Michelmore, S Cesari, S Krattinger, S Seeholzer, T Inukai, T Maekawa, T Nürnberger, T Toojinda, T Wicker, TJ Close, U Lundqvist, V Pahalawatta, W Straib, WR Bushnell, X Sui, Y Tosa, Y Tosa   +62 more
core   +1 more source

Clinical, histological, and serological predictors of renal function loss in lupus nephritis.

Arthritis Care &Research, Accepted Article.
Objective Kidney survival is the ultimate goal in lupus nephritis (LN) management, but long‐term predictors remain inadequately studied, requiring long‐term follow‐up. This study aimed to identify baseline and early longitudinal predictors of kidney survival in the Accelerating Medicines Partnership LN longitudinal cohort.
Shangzhu Zhang, Laurence Magder, Daniel Goldman, Judith A. James, Joel M Guthridge, Carla Guthridge, Peter Izmirly, Jill P Buyon, H.Michael Belmont, Richard A. Furie, Noa Schwartz, Chaim Putterman, Jennifer L. Barnas, Jennifer H. Anolik, Sarah French, Maria Dall'era, Avi Z. Rosenberg, Jeffrey Hodgin, Dawit S. Demeke, the Accelerating Medicines Partnership RA/SLE Network, Michelle Petri, Andrea Fava   +21 more
wiley   +1 more source

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

Communications Biology, 2022
This review discusses emerging roles for the NLR family pyrin domain containing 6 receptor (NLRP6) in intestinal homeostasis, inflammation, cancer, the nervous system and liver disease.
Diego Angosto-Bazarra, Cristina Molina-López, Pablo Pelegrín   +2 more
doaj   +1 more source

The Lick AGN Monitoring Project: Alternate Routes to a Broad-line Region Radius [PDF]

, 2010
It is now possible to estimate black hole masses across cosmic time, using broad emission lines in active galaxies. This technique informs our views of how galaxies and their central black holes coevolve.
Aaron J. Barth, Alexander, Alexei V. Filippenko, Bennert, Bennert, Bentz, Bentz, Bentz, Bentz, Bentz, Bentz, Bentz, Blackburne, Carol E. Hood, Collier, Dasyra, Davies, Denney, Denney, Desroches, Diamond-Stanic, Dietrich, Dietrich, Elinor Gates, Ferrarese, Gallimore, Gebhardt, Greene, Greene, Greene, Greene, Greene, Greene, Gültekin, Hicks, Ho, Hopkins, Jahnke, Jenny E. Greene, Jonelle L. Walsh, Jong-Hak Woo, Kaspi, Kaspi, Kelly, Kollmeier, Kuo, Liu, Marconi, Marconi, Matthew A. Malkan, McGill, Meléndez, Misty C. Bentz, Morgan, Murray, Nelson, Netzer, Netzer, Onken, Onken, Peng, Peng, Peterson, Peterson, Peterson, Peterson, Salviander, Schmitt, Schmitt, Shapiro, Shen, Shen, Shields, Silk, Steffen, Tanaka, Timmer, Tommasin, Tommaso Treu, Tremaine, Treu, Treu, Ueda, Ulrich, Vardha N. Bennert, Veilleux, Vestergaard, Vestergaard, Walsh, Walter, Woo, Woo, Woo   +92 more
core   +3 more sources

RNF213 Is an Interferon‐Stimulated Gene That Targets Influenza A Virus NP and Activates MDA5 to Restrict Infection

Advanced Science, EarlyView.
RNF213 is characterized as a dual‐functional antiviral effector. It directly mediates the degradation of the influenza A virus nucleoprotein (NP) while simultaneously activating the MDA5‐mediated innate immune signaling pathway. This coordinated response establishes a powerful host defense system against viral infection. ABSTRACT Influenza A virus (IAV)
Haoning Li, Yuying Zhang, Jingjing Wang, Qianqian Zhang, Hailiang Sun, Fanhua Wei   +5 more
wiley   +1 more source

The Role of NOD-like Receptors in Recognition of Pathogen-associated Molecular Patterns of Infectious Pathogens and in Development of Inflammation. Part 1. NLR family

Zdorovʹe Rebenka, 2013
The characteristic of the family of pattern-recognizing receptors — NLR — is presented in the review.
A.Ye. Abaturov, A.P. Volosovets, Ye.I. Yulish   +2 more
doaj   +1 more source

The Predictive Value of the Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratio in Patients with Recurrent Idiopathic Granulomatous Mastitis

European Journal of Breast Health, 2020
Objective: The aim of this study was to investigate the relationship between the inflammatory parameters including neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) and the prognosis of idiopathic granulomatous mastitis (IGM ...
Ömer Arda Çetinkaya, Süleyman Utku Çelik, Serdar Gökay Terzioğlu, Aydan Eroğlu   +3 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

Advanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang, Xinyan Sun, Yingchao Sun, Zeqiang Cheng, Zixiang Cheng, Shengbo Han, Ying Feng, Wenbo Yang, Huimin Li, Meichen Zhu, Xiaoling Wu, Jinghua Zhang, Jihua Tang, Honglian Li, Yanyong Cao, Canxing Duan, Yan Shi   +16 more
wiley   +1 more source