Results 101 to 110 of about 4,243,571 (286)

NLR family pyrin domain containing 3 (NLRP3) inflammasome gene polymorphism rs7512998 (C>T) predicts aging-related increase of blood pressure, the TAMRISK study

Immunity & Ageing, 2015
BackgroundThe activation of NLR family pyrin domain containing 3 (NLRP3) inflammasome by cellular stress leads to activation of the inflammasome, and NLRP3 gene polymorphisms have been associated with autoinflammatory diseases.
T. Kunnas, Kirsi Määttä, S. Nikkari   +2 more
semanticscholar   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

Possible utility of neutrophil/lymphocyte ratio as a predictor of suicidal risk in mood disorders

European Psychiatry, 2022
Introduction Correlations between neutrophil/lymphocyte, platelet/lymphocyte, and monocyte/lymphocyte ratios (NLR, PLR, and MLR, respectively) and psychopathological and clinical variables in the context of mood disorders are increasingly emerging in ...
W. Flamini, S. Torrigiani, F. Mucci, T. Ivaldi, D. Marazziti, L. Dell’Osso   +5 more
doaj   +1 more source

Functional requirement of the Arabidopsis importin-α nuclear transport receptor family in autoimmunity mediated by the NLR protein SNC1

bioRxiv, 2020
IMPORTIN-α3/MOS6 (MODIFIER OF SNC1, 6) is one of nine importin-α isoforms in Arabidopsis that recruit nuclear localization signal (NLS)-containing cargo proteins to the nuclear import machinery.
Daniel Lüdke, Charlotte Roth, Sieglinde A. Kamrad, Jana Messerschmidt, Denise Hartken, J. Appel, Bojan F. Hörnich, Qiqi Yan, S. Kusch, Melanie Klenke, A. Gunkel, L. Wirthmueller, M. Wiermer   +12 more
semanticscholar   +1 more source

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

The Effect of Self-gravity of Gas on Gas Fueling in Barred Galaxies with a Supermassive Black Hole

, 1998
In our previous paper, we have shown that a gas disk in the nuclear region of a barred galaxy which contains a central supermassive black hole (SMBH) rapidly evolves into a nuclear gas ring by the effect of an additional inner Lindblad resonance caused ...
Fukuda, Hiroyuki, Habe, Asao, Wada, Keiichi   +2 more
core   +1 more source

MicroRNA regulation of bovine monocyte inflammatory and metabolic networks in an in vivo infection model. [PDF]

, 2014
peer-reviewedBovine mastitis is an inflammation-driven disease of the bovine mammary gland that costs the global dairy industry several billion dollars per annum.
Baker, Mike, Bryan, Kenneth, Lawless, Nathan, Lippolis, John D., Lynn, David J, O'Farrelly, Cliona, Pesch, Bruce, Reinhardt, Timothy A., Sonstegard, Tad, Zimmerman, Duane, Zuelke, Kurt   +10 more
core   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Characterizing Multi-Scale Self-Similar Behavior and Non-Statistical Properties of Financial Time Series

, 2010
We make use of wavelet transform to study the multi-scale, self similar behavior and deviations thereof, in the stock prices of large companies, belonging to different economic sectors. The stock market returns exhibit multi-fractal characteristics, with
Bouchaud, Burke, Campbell, Daubechies, Eadie, Farge, Gabaix, Ghashghaie, Gopikrishnan, Ivanov, Kantelhardt, Kolmogorov, Laloux, Mallat, Mallat, Mandelbrot, Mandelbrot, Manimaran, Manimaran, Manimaran, Manimaran, Mantegna, Mantegna, Mantegna, Marsaglia, Massey, Matia, Melo, Miller, P. Manimaran, Panigrahi, Plerou, Plerou, Podobnik, Podobnik, Podobnik, Podobnik, Prasanta K. Panigrahi, Santhanam, Sayantan Ghosh, Sengupta, Smirnoff, Sornette, Torrence   +43 more
core   +1 more source

The 'Humour' element in engineering lectures across cultures:An approach to pragmatic annotation [PDF]

, 2016
Humour is one of the most difficult pragmatic devices for lecturers and students to engage with, and for researchers to identify systematically. Humour does not always travel well across cultures.
Alsop, Sian
core   +1 more source