Results 111 to 120 of about 87,795 (274)
NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function
Over the last decade, significant progress has been achieved in defining mechanisms underlying NLR regulation of immune system function. However, several NLR family members continue to defy our best attempts at characterization and routinely exhibit ...
Margaret A. Nagai-Singer +3 more
doaj +1 more source
Sequential Monte Carlo simulation for the estimation of small reachability probabilities for stochastic hybrid systems [PDF]
The problem of estimating the probability that a system reaches a given set within some time horizon is considered. Standard Monte Carlo methods for reachability probability estimation do not require specific assumptions on the system under consideration.
Krystul, J., Blom, H.A.P.
core
Russian wheat aphid: a model for genomic plasticity and a challenge to breeders
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn +8 more
wiley +1 more source
NLR regulation of the TSC family.
Both NOD2 and NLRC4 could influence or control expression of TSC22D nutrient sensor genes including control of TSC22D4 by NOD2.
openaire +2 more sources
Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri +11 more
wiley +1 more source
Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari +10 more
wiley +1 more source
NLR (NOD-like receptor) is a pattern recognition receptors (PRRs) and is crucial in the innate immune response. It identifies pathogen-associated molecular patterns (PAMPs) and modulates associated immune pathways.
Xiaochen Zhu +4 more
doaj +1 more source
Evolutionary Convergence and Divergence in NLR Function and Structure
The recognition of cellular damage caused by either pathogens or abiotic stress is essential for host defense in all forms of life in the plant and animal kingdoms.
Etienne Meunier +3 more
core +1 more source
Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation
During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu +10 more
wiley +1 more source
The NLR family pyrin domain containing 3 inflammasome in the mechanism of electroacupuncture: Current status and future perspectives. [PDF]
Yuan M, Wang D, Yang J, Lan H.
europepmc +1 more source

