Results 131 to 140 of about 90,508 (248)

NLR Family Member X1 [PDF]

, 2020
openaire   +1 more source

Multi‐omics analyses reveal host–microbe interactions in atopic dermatitis and psoriasis

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Atopic dermatitis (AD) and psoriasis (PSO) are chronic inflammatory skin diseases with complex host–microbe interactions. This study analysed skin samples from patients and healthy individuals using integrated microbial and transcriptomic profiling. Both diseases showed disrupted fungal–bacterial interactions and alterations in host immune responses ...
Ying Yang, Peter Olah, Alexander Salava, Jonathan Barker, Antti Lauerma, Björn Andersson, Nanna Fyhrquist, Bernhard Homey, Harri Alenius   +8 more
wiley   +1 more source

AR-A014418, a glycogen synthase kinase-3β inhibitor, mitigates lipopolysaccharide-induced inflammation in rat dental pulp stem cells via NLR family pyrin domain containing 3 inflammasome impairment. [PDF]

J Dent Sci, 2023
Xie H, Lin Y, Fang F.
europepmc   +1 more source

RING E3 ligase SNIPER8 functions redundantly with three close homologs to regulate the turnover of transcriptional co‐repressor TPR1

Journal of Integrative Plant Biology, EarlyView.
The Arabidopsis E3 ligase SNIPER8 negatively regulates immunity by promoting ubiquitination and proteasomal degradation of the transcriptional corepressor TOPLESS‐RELATED1, limiting excessive immune responses, maintaining immune homeostasis, and balancing defense activation and normal plant growth.
Xueru Liu, Paul Kapos, Zhongshou Wu, Yujun Peng, Meixuezi Tong, Asana Khajavi, Yan Huang, Yuelin Zhang, Xin Li   +8 more
wiley   +1 more source

Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression. [PDF]

Bioengineered, 2022
Wang B, Liu Y, Jiang R, Liu Z, Gao H, Chen F, Mei J.   +6 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

Galangin Enhances Anticancer Efficacy of 5-Fluorouracil in Esophageal Cancer Cells and Xenografts Through NLR Family Pyrin Domain Containing 3 (NLRP3) Downregulation. [PDF]

Med Sci Monit, 2021
Zhang C, Luo CL, Shang GS, Jiang DX, Song Q.   +4 more
europepmc   +1 more source

NLR family member X1 (NLRX1) [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Phloridzin Mitigates Aging‐Associated Periodontitis by Restraining Inflammatory Cell Death

Journal of Periodontal Research, EarlyView.
Phloridzin attenuated oxidative stressinduced senescence, inflammatory responses, and osteogenic dysfunction in HPDLCs. In an aging‐associated experimental periodontitis model, phloridzin alleviated alveolar bone loss, suggesting its potential to maintain periodontal tissue integrity under aging‐related inflammatory conditions.
Da Eun Lee, Eun‐Nam Kim, Gil‐Saeng Jeong   +2 more
wiley   +1 more source

Activation of NLR family, domain of pyrin containing 3 inflammasome by nitrous oxide through thioredoxin-interacting protein to induce nerve cell injury. [PDF]

Bioengineered, 2021
Liu W, Zhang G, Sun B, Wang S, Lu Y, Xie H.   +5 more
europepmc   +1 more source