β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows. [PDF]
Front Vet Sci, 2022 Dong Z +9 more
europepmc +1 more source
“Hold on, I'm comin'”: Copyright, political campaigns, and the limits of songwriter control
The Journal of World Intellectual Property, EarlyView.Abstract This article examines how songwriters in the United States object to the unwanted performance of their musical works at live political events, and the legal options available to challenge such uses. Prompted by the repeated use of ‘Hold On, I'm Comin'’ as outro music at Donald Trump's campaign events between 2020 and 2024, and the recent ...
Joel Cooper, Marie Hadley
wiley +1 more source
The Inflammasome NLR Family Pyrin Domain-Containing Protein 3 (NLRP3) as a Novel Therapeutic Target for Idiopathic Pulmonary Fibrosis. [PDF]
Am J Pathol, 2022 Colunga Biancatelli RML +2 more
europepmc +1 more source
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility
Molecular Microbiology, EarlyView.Motility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Fatemeh Mohaghegh +2 more
wiley +1 more source
LURP1, a SARD1‐regulated protein, coordinates with the helper NLR ADR1 to promote plant immunity
New Phytologist, EarlyView.The working model of LURP1 function in plant immunity. Upon pathogen infection, SARD1/CBP60g promotes the transcription of LURP1 directly. LURP1 likely functions as an adaptor protein that associates with the PRRs–BAK1 complexes at the plasma membrane (PM) while also interacts with the ADR1 family helper NLRs.
Xueru Liu +7 more
wiley +1 more source
Frontiers in Cardiovascular MedicineObjectiveThe aim of this paper was to investigate the correlation between neutrophil/lymphocyte (NLR), monocyte/lymphocyte (MLR), and CRP/ALB ratios with the degree of coronary artery disease and their predictive value.MethodsThis study retrospectively ...
Mingming Zhao +3 more
doaj +1 more source
FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway. [PDF]
Exp Anim, 2023 Wei J +5 more
europepmc +1 more source
Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole‑kindled mice. [PDF]
Int J Mol Med, 2021 Wang L +10 more
europepmc +1 more source
Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction
Obesity Reviews, EarlyView.Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey +7 more
wiley +1 more source
Long noncoding RNA X-inactive specific transcript regulates NLR family pyrin domain containing 3/caspase-1-mediated pyroptosis in diabetic nephropathy. [PDF]
World J Diabetes, 2022 Xu J +6 more
europepmc +1 more source