Results 151 to 160 of about 4,243,571 (286)

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

Molecular Signatures of Peripheral and Central Dental Pulp Subpopulations in Response to Streptococcus mutans: A Bulk RNA‐Seq Analysis

International Endodontic Journal, EarlyView.
ABSTRACT Aim The dental pulp is an immunologically active tissue that responds dynamically to cariogenic challenge. Peripheral pulp cells adjacent to dentine encounter bacterial stimuli earlier than cells located in the central pulp. To investigate signalling and immune interactions, this study profiled the transcriptomes of dentine‐adherent cells ...
Sandra Pohl, Maximilian L. Huber, Tobias Akamp, Andreas Rosendahl, Melanie Linnebank, Lea Schreiber, Claudia Gebhard, Nicholas Strieder, Michael Rehli, Wolfgang Buchalla, Matthias Widbiller   +10 more
wiley   +1 more source

The association between inflammatory markers in routine blood counts at 1 year and attention‐deficit/hyperactivity disorder (ADHD): A case–control study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Attention‐deficit/hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder marked by persistent patterns of inattention, disorganization, hyperactivity, and impulsivity. Increasing evidence implicates immune‐inflammatory processes in its etiology, with observed associations between ADHD and infectious diseases, allergic ...
Eugene Merzon, Ariel Israel, Shelly Salminis‐Linzen, Eli Magen, Akim Geishin, Shlomo Vinker, Ilan Green, Avivit Golan‐Cohen, Shai Ashkenazi, Stephen V. Faraone, Abraham Weizman, Iris Manor   +11 more
wiley   +1 more source

Effects of early pregnancy on NOD-like receptor expression in the ovine endometrium

Frontiers in Veterinary Science
IntroductionNucleotide-binding domain (NOD)-like receptors (NLRs) are expressed in the endometrium, and involved in modulating the female innate immune responses.
Leying Zhang, Jiabao Cai, Xinxin Wang, Zhen Yang, Haiquan Ding, Ling Yang   +5 more
doaj   +1 more source

β-hydroxybutyrate impairs monocyte function via the ROS-NLR family pyrin domain-containing three inflammasome (NLRP3) pathway in ketotic cows. [PDF]

Front Vet Sci, 2022
Dong Z, Sun X, Tang Y, Luo S, Jia H, Xu Q, Jiang Q, Loor JJ, Xu W, Xu C.   +9 more
europepmc   +1 more source

Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change

Journal of Integrative Plant Biology, EarlyView.
This review covers recent progress in the understanding of stress‐responsive regulatory networks in soybean and highlights emerging genomic and breeding strategies. Integrating molecular insights and precision breeding will help to accelerate the development of climate‐resilient soybean cultivars.
Ali Shahzad, Monan Sun, Shuangkang Pei, Xiaoyu Liu, Yinhe Zhang, Keheng Xu, Hongtao Gao, Yonggang Zhou, Haiyan Li   +8 more
wiley   +1 more source

The Inflammasome NLR Family Pyrin Domain-Containing Protein 3 (NLRP3) as a Novel Therapeutic Target for Idiopathic Pulmonary Fibrosis. [PDF]

Am J Pathol, 2022
Colunga Biancatelli RML, Solopov PA, Catravas JD.   +2 more
europepmc   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source

FERM domain containing kindlin 1 knockdown attenuates inflammation induced by intracerebral hemorrhage in rats via NLR family pyrin domain containing 3/nuclear factor kappa B pathway. [PDF]

Exp Anim, 2023
Wei J, Yin J, Cui Y, Wang K, Hong M, Cui J.   +5 more
europepmc   +1 more source

Coalitional Manipulation on Communication Network [PDF]

In an abstract model of division problems, we study division rules that are not manipulable through a reallocation of individual characteristic vectors within a coalition (e.g. reallocation of claims in bankruptcy problems).
Biung-Ghi Ju
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