Results 141 to 150 of about 4,243,571 (286)
NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function
Frontiers in Immunology, 2019 Over the last decade, significant progress has been achieved in defining mechanisms underlying NLR regulation of immune system function. However, several NLR family members continue to defy our best attempts at characterization and routinely exhibit ...
Margaret A. Nagai-Singer +3 more
doaj +1 more source
Allergy, EarlyView.Imaging mass cytometry shows lupus panniculitis lesions are dominated by cytotoxic and skin‐homing T cells with abundant macrophages and B‐cell aggregates. Spatial neighborhood analysis reveals organized leukocyte architecture, including B‐cell proximity to naïve T cells and M1 macrophages to cytotoxic T cells.
Milad Ameri +11 more
wiley +1 more source
Measuring complexity in a business cycle [PDF]
, 2009 The purpose of this paper is to study the dynamical behavior of a family of two- dimensional nonlinear maps associated to an economic model. Our objective is to measure the complexity of the system using techniques of symbolic dynamics in order to ...
Duarte, Jorge +2 more
core
Brain Pathology, EarlyView.Neuritic plaques increase in the intermediate stage of Alzheimer's neuropathological change. The intermediate stage of Alzheimer's disease was investigated by transcriptomics and immunohistochemistry. This revealed that inflammasome sensors NLRP1, NLRP3, and AIM2 oligomerize with ASC speck to form the inflammasome complex and initiate the downstream ...
Juan Pablo de Rivero Vaccari +10 more
wiley +1 more source
Comparative Immunology ReportsNLR (NOD-like receptor) is a pattern recognition receptors (PRRs) and is crucial in the innate immune response. It identifies pathogen-associated molecular patterns (PAMPs) and modulates associated immune pathways.
Xiaochen Zhu +4 more
doaj +1 more source
Recognition of extracellular bacteria by NLRs and its role in the development of adaptive immunity
Frontiers in Immunology, 2013 Innate immune recognition of bacteria is the first requirement for mounting an effective immune response able to control infection. Over the previous decade, the general paradigm was that extracellular bacteria were only sensed by cell surface-expressed ...
Jonathan eFerrand, Richard Louis Ferrero
doaj +1 more source
Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging
Cancer Science, EarlyView.Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka +4 more
wiley +1 more source
Constraining the size of the narrow line region in distant quasars
, 2006 We propose a proper method to measure the size of the narrow line region (NLR) in distant quasars. The apparent angular size of the NLR is, in general, too small to resolve technically. However, it is possible to map the NLR if with gravitational lensing.
Adam G. +3 more
core +2 more sources
Lactate Accelerates Early Angiogenesis and Bone Regeneration Through Macrophage M1 Polarisation
Cell Proliferation, EarlyView.During the early stage of bone defect healing, lactate accumulates and contributes to increasing NOD1 expression by stabilising HIF1α that in turn triggers a calcium influx, which ultimately polarises macrophages towards the M1 phenotype and accelerates vascularisation of endothelial cells.
Lulu Liu +10 more
wiley +1 more source
Didymin, a natural flavonoid, relieves the progression of myocardial infarction via inhibiting the NLR family pyrin domain containing 3 inflammasome. [PDF]
Pharm Biol, 2022 Zhang Y, RuXian G.
europepmc +1 more source