Results 91 to 100 of about 4,243,571 (286)

Tracing the path from conservation to expansion evolutionary insights into NLR genes in oleaceae

open access: yesBMC Plant Biology
The Oleaceae family, encompassing key genera such as Fraxinus (ash trees), Olea (olives), Jasminum (jasmine), Syringa (lilac), and Forsythia, plays a crucial ecological and economic role.
Saba Parvez   +10 more
doaj   +1 more source

Phylogenomics of Plant NLR Immune Receptors to Identify Functionally Conserved Sequence Motifs

open access: yesBio-Protocol
In recent years, the increase in genome sequencing across diverse plant species has provided a significant advantage for phylogenomics studies, allowing the analysis of one of the most diverse gene families in plants: nucleotide-binding leucine-rich ...
Toshiyuki Sakai   +2 more
doaj   +1 more source

Plant NLRs: The Whistleblowers of Plant Immunity

open access: yesPlant Communications, 2020
The study of plant diseases is almost as old as agriculture itself. Advancements in molecular biology have given us much more insight into the plant immune system and how it detects the many pathogens plants may encounter.
Solveig van Wersch   +3 more
doaj   +1 more source

ASC filament formation serves as a signal amplification mechanism for inflammasomes [PDF]

open access: yes, 2016
A hallmark of inflammasome activation is the ASC speck, a micrometre-sized structure formed by the inflammasome adaptor protein ASC (apoptosis-associated speck-like protein containing a CARD), which consists of a pyrin domain (PYD) and a caspase ...
Broz, Petr   +4 more
core   +1 more source

Nanopore adaptive sampling to identify the NLR-gene family in melon (Cucumis meloL.)

open access: yesBMC Genomics, 2023
AbstractBackgroundNanopore Adaptive Sampling (NAS) offers a promising approach for assessing genetic diversity in targeted genomic regions. Herein, we design and validate an experiment to enrich a set of resistance genes in several melon cultivars as a proof of concept.ResultsWe showed that each of the 15 regions we identified in two newly assembled ...
Javier Belinchon-Moreno   +13 more
openaire   +5 more sources

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

open access: yesAdvanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou   +17 more
wiley   +1 more source

NOD-like receptors in fish: evolution, structure, immune signaling, and targeting for aquaculture vaccine adjuvants

open access: yesFrontiers in Immunology
Teleost fish possess a highly diverse innate immune system, which is well-adapted to the pathogen-rich aquatic environment in which they reside. NOD-like receptors (NLRs), a conserved family of cytosolic pattern recognition receptors, are at the center ...
Banikalyan Swain, Kavi R. Miryala
doaj   +1 more source

The role of NOD-like receptors in innate immunity

open access: yesFrontiers in Immunology, 2023
The innate immune system in vertebrates and invertebrates relies on conserved receptors and ligands, and pathways that can rapidly initiate the host response against microbial infection and other sources of stress and danger.
Cássio Luiz Coutinho Almeida-da-Silva   +3 more
doaj   +1 more source

4‐Hydroxybenzyl Alcohol Mitigates Hyperlipidemia‐Associated Depression by Inhibiting Neuroinflammation via the NKIRAS2/NF‐κB Pathway

open access: yesAdvanced Science, EarlyView.
4‐HBA upregulates NKIRAS2 levels, inhibiting the activation of the NF‐κB pathway and subsequently reducing the levels of neuroinflammatory markers. This modulation helps restore normal mood and behavior in hyperlipidemic conditions, providing a potential therapeutic strategy for managing hyperlipidemia‐associated depression.
Ying Zhang   +7 more
wiley   +1 more source

Advances in Plant-Nematode Interactions with Emphasis on the Notorious Nematode Genus Meloidogyne. [PDF]

open access: yes, 2019
Plant infections by plant-parasitic nematodes (PPNs) continue to be one of the major limitations in agricultural systems. Root-knot nematodes (RKNs), belonging to the genus Meloidogyne, are one of the most important groups of PPNs worldwide.
Kaloshian, Isgouhi, Teixeira, Marcella
core  

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