Results 91 to 100 of about 90,508 (248)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Bisphenol A and Its Analogs: Toxicity Analysis in Mouse and Rat Liver—A Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA) and its analogs are widely recognized for their use in industry and plastic manufacturing. Consequently, humans and animals are continually exposed to various substances in their daily lives. This review evaluates the hepatic toxicity of BPA and its analogs in mice and rats, with particular emphasis on molecular mechanisms ...
Sevda Bagdatli, Muhammed Canik, Gizem Gencay, Nurbanu Zengin, Tarık Dinc, Nazan Deniz Yön   +5 more
wiley   +1 more source

MicroRNA‐Mediated Autophagy and Cardiovascular Diseases: Exploring the Crossroads of Atherosclerosis and Beyond

Journal of Clinical Laboratory Analysis, EarlyView.
This graphical abstract illustrates the dynamic bidirectional crosstalk between microRNA biogenesis and autophagy, which serves as a critical regulatory axis in cardiovascular homeostasis. We highlight how specific miRNAs modulate autophagic flux to mitigate vascular inflammation and plaque instability, while concurrently, the autophagic machinery ...
Sepehr Ebrahimi‐Dehkordi, Amir Hossein Barjasteh, Aida Zarei, Sina Bazmi, Sarah Vaseghi, Sara Ashna, Amirreza Solati, Ali Yousefzadeh, Bita Safarzadeh Nasrabad, Zahra Mohammadi, Hamed Haddad Kashani, Mohammad Hossein Pourhanifeh   +11 more
wiley   +1 more source

Machine Learning–Based Comparative Analysis of Blood Cell–Derived Inflammatory Indices for Predicting MAFLD and Liver Fibrosis: Evidence From NHANES 2017–2020

Journal of Clinical Laboratory Analysis, EarlyView.
This research assesses the correlations and diagnostic efficacy of blood cell‐derived inflammatory indicators in predicting metabolic dysfunction‐associated fatty liver disease (MAFLD) and liver fibrosis using NHANES 2017–2020 data. AISI had the highest predictive capability for MAFLD, while PLR served as the most efficacious indicator for fibrosis ...
Hao Chen, Qinmei Chen, Xiangqian Wang, Yixian He, Xiqiao Zhou   +4 more
wiley   +1 more source

NOD2 Deficiency Protects against Cardiac Remodeling after Myocardial Infarction in Mice

Cellular Physiology and Biochemistry, 2013
Background/Aims: Although the pathogenesis of myocardial infarction (MI) is multifactorial, activation of innate immune system to induce inflammation has emerged as a key pathophysiological process in MI.
Xiang Li, Fengli Li, Yongli Chu, Xiaojie Wang, Hongyu Zhang, Yanyan Hu, Yan Zhang, Ziying Wang, Xinbing Wei, Wencheng Jian, Xiumei Zhang, Fan Yi   +11 more
doaj   +1 more source

Visual Patterns of Diaphragmatic Motion in Acute Respiratory Failure: A Prospective Pilot Study

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 421-428, March/April 2025.
In this prospective bicentric study, we studied the relationship between the appearance of diaphragmatic motion and the etiological diagnosis of patients admitted to the emergency department with ARF. We observed a different visual pattern in patients with pneumonia. This is an interesting result as it allows the diagnosis of pneumonia without the need
Thibaut Markarian, Matthieu Daniel, Kevin Guillemet, Florian Ajavon, Florent Femy, Romain Genre Grandpierre, Anne‐Laure Feral‐Pierssens, Xavier Bobbia   +7 more
wiley   +1 more source

Interleukin‐37 Enhances Liver NK Cell Cytotoxicity and Improves Recurrence‐Free Survival in Hepatocellular Carcinoma Patients

Journal of Hepato-Biliary-Pancreatic Sciences, EarlyView.
ABSTRACT Introduction Hepatocellular carcinoma (HCC) remains a major cause of cancer‐related mortality worldwide, and postoperative recurrence continues to limit long‐term survival. Liver‐resident natural killer (NK) cells are key effectors of antitumor immunity in the hepatic microenvironment. Interleukin‐37 (IL‐37), an anti‐inflammatory cytokine, has
Yuki Imaoka, Masahiro Ohira, Yuka Tanaka, Toshihiro Nakayama, Miho Akabane, Shinichiro Yokota, Sheri M. Krams, Olivia M. Martinez, Carlos O. Esquivel, Kazunari Sasaki, Hideki Ohdan   +10 more
wiley   +1 more source

Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi, Nishant Pandey, Sushan Ghimire, Avilasha Shah, Anurag Tiwari, Salina Subedi, Deepika Neupane   +6 more
wiley   +1 more source

Genome-wide identification of NOD-like receptor genes in redclaw crayfish (Cherax quadricarinatus) and their responses to DIV1 infection

Aquaculture Reports
Nucleotide-binding and oligomerization domain (NOD)-like receptors (NLRs), classified as pattern recognition receptors (PRRs), play crucial roles in innate immune responses. However, research on this topic in crustaceans remains limited.
He Chang-Xi, Zheng Jian-Bo, Yucheng Zhang, Liu Shi-Li, Jiang Wen-Ping, Chi Mei-Li, Cheng Shun, Li Fei, Jia Yong-Yi   +8 more
doaj   +1 more source

NLRX1 Is a Multifaceted and Enigmatic Regulator of Immune System Function

Frontiers in Immunology, 2019
Over the last decade, significant progress has been achieved in defining mechanisms underlying NLR regulation of immune system function. However, several NLR family members continue to defy our best attempts at characterization and routinely exhibit ...
Margaret A. Nagai-Singer, Holly A. Morrison, Irving C. Allen, Irving C. Allen   +3 more
doaj   +1 more source