Results 131 to 140 of about 134,694 (275)

The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins. [PDF]

Int J Mol Sci, 2021
León Machado JA, Steimle V.
europepmc   +1 more source

GLIM criteria for the diagnosis of malnutrition in patients with cirrhosis: A narrative review

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background This narrative review aims to describe and discuss the validity of the Global Leadership Initiative on Malnutrition (GLIM) criteria in patients with cirrhosis. Methods The literature search was performed in PubMed and EMBASE between May and August 2024 and updated in January 2025, including original studies published in English in ...
Bárbara Chaves Santos, Ana Teresa Limon‐Miro, Puneeta Tandon, Maria Isabel Toulson Davisson Correia, Carla M. Prado, Maria Cristina Gonzalez, Lucilene Rezende Anastácio   +6 more
wiley   +1 more source

Admission Plasma Lipopolysaccharide‐binding protein, Procalcitonin, and Lactate for Early Identification of Nosocomial Infection in Cirrhotic Patients With Upper Gastrointestinal Bleeding: A Retrospective Analysis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to assess whether admission plasma lipopolysaccharide‐binding protein (LBP), procalcitonin (PCT), and lactate could improve detection of nosocomial infection in cirrhotic patients presenting with upper gastrointestinal bleeding (UGIB).
Li Chen, Shan‐Shan Dun, Fang Xiao
wiley   +1 more source

Filamentation activates bacterial NLR-like antiviral protein

AbstractBacterial antiviral STANDs (Avs) are evolutionarily related to the nucleotide-binding leucine-rich repeat containing receptors (NLRs) widely distributed in immune systems across animals and plants.EfAvs5, an Avs type 5 protein fromEscherichia fergusonii, contains an N-terminal SIR2 effector domain, a nucleotide-binding oligomerization domain ...
Jianting Zheng, Yiqun Wang, Yuqing Tian, Xu Yang, Feng Yu   +4 more
openaire   +1 more source

Wheat zinc finger protein TaZF interacts with both the powdery mildew AvrPm2 protein and the corresponding wheat Pm2a immune receptor

Plant Communications
Plant defense responses to pathogens are induced after direct or indirect perception of effector proteins or their activity on host proteins. In fungal–plant interactions, relatively little is known about whether, in addition to avirulence effectors and ...
Beatrice Manser, Helen Zbinden, Gerhard Herren, Joel Steger, Jonatan Isaksson, Stephanie Bräunlich, Thomas Wicker, Beat Keller   +7 more
doaj   +1 more source

Triglyceride‐Glucose Index‐Based Nomogram for Predicting Short‐Term Mortality in Sepsis Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The triglyceride‐glucose (TyG) index, a marker of insulin resistance, is associated with outcomes in critical illness; however, its predictive role for 28‐day mortality in Asian patients with sepsis has not been established. To address this, the current investigation was designed to evaluate its prognostic significance and to construct a risk ...
Jing Zhang, Yu‐Jing Jiang, Ya‐Ting Lv, Tong‐Qin Li, Li Ma   +4 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

Med Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang, Ge Zhang, Tian‐Ding Liu, Tianshu Gu, Fengyi Yu, Pengyuan Xu, Wunan Mi, Xuanjiang Zhao, Qian Guo, Honglin Zheng, Taiqi Zhao, Qiang Li, Di Lu, Mingxuan Duan, Chaoyang Yu, Ruhao Wu, Shiqian Zhang, Haonan Zhang, Zeyu Wang, Youyang Zheng, Yan Xiao, Zenglei Zhang, Ge Zhang   +22 more
wiley   +1 more source

NLRX1: Versatile functions of a mitochondrial NLR protein that controls mitophagy

Biomedical Journal
NLRX1 is a member of the of the Nod-like receptor (NLR) family, and it represents a unique pattern recognition molecule (PRM) as it localizes to the mitochondrial matrix in resting conditions. Over the past fifteen years, NLRX1 has been proposed to regulate multiple cellular processes, including antiviral immunity, apoptosis, reactive oxygen species ...
Paul Y. Bi, Samuel A. Killackey, Linus Schweizer, Stephen E. Girardin   +3 more
openaire   +3 more sources

White Adipose Tissue Browning and Cross Talk With Metabolic Diseases and Tumors: From Molecular Mechanisms to Clinical Translation

Med Research, EarlyView.
White adipose tissue undergoes browning under endogenous and exogenous stimuli, primarily regulated by core molecules such as PRDM16 and UCP1. It exhibits a double‐edged sword effect in metabolic diseases and tumors: while mitigating metabolic disease impacts and suppressing early‐stage tumors through nutritional competition, it may accelerate cachexia
Yingjiao Wang, Diyuan Zhang, Yuqin Zhou, Ling Qian, Yan Wang, Lei Peng, Min Zhao, Hao Tian, Zhenyu Wu, Aiqi Tang, Minghao Sun, Yi Zhang, Xiaowei Qi   +12 more
wiley   +1 more source

Phylogenomics of Plant NLR Immune Receptors to Identify Functionally Conserved Sequence Motifs

Bio-Protocol
In recent years, the increase in genome sequencing across diverse plant species has provided a significant advantage for phylogenomics studies, allowing the analysis of one of the most diverse gene families in plants: nucleotide-binding leucine-rich ...
Toshiyuki Sakai, AmirAli Toghani, Hiroaki Adachi   +2 more
doaj   +1 more source