Results 91 to 100 of about 86,244 (257)

The soybean plasma membrane GmDR1 protein conferring broad-spectrum disease and pest resistance regulates several receptor kinases and NLR proteins

Scientific Reports
Overexpression of Glycine max disease resistant 1 (GmDR1) exhibits broad-spectrum resistance against Fusarium virguliforme, Heterodera glycines (soybean cyst nematode), Tetranychus urticae (Koch) (spider mites), and Aphis glycines Matsumura (soybean ...
Micheline N. Ngaki, Subodh K. Srivastava, Wang Feifei, Madan K. Bhattacharyya   +3 more
doaj   +1 more source

Genome-wide identification and functional characterization of NOD-like receptors (NLRs) in snakehead (Channa argus)

Comparative Immunology Reports
NLR (NOD-like receptor) is a pattern recognition receptors (PRRs) and is crucial in the innate immune response. It identifies pathogen-associated molecular patterns (PAMPs) and modulates associated immune pathways.
Xiaochen Zhu, Beibei Wang, Lu Zhang, Xiaoyan Zhang, Chao Li   +4 more
doaj   +1 more source

HPV Serology and Circulating Viral DNA for Detection, Genotyping, and Measurement of Disease Burden in Oropharyngeal Cancer

International Journal of Cancer, EarlyView.
ABSTRACT The incidence of human papillomavirus‐positive (HPV+) oropharyngeal cancer (OPC) has increased rapidly, and HPV early antigen serology has been proposed as a scalable and cost‐effective early detection test. HPV seropositivity can precede clinical presentation of OPC by several years, so additional surveillance procedures may be necessary to ...
Lucas Penny, Eric Yang Stutheit‐Zhao, Birgitta E. Michels, Fabian Rosing, Zhen Zhao, Yangqiao Zheng, Jinfeng Zou, Shao Hui Huang, Johnny Carlton, Andrew McPartlin, John R. de Almeida, David Goldstein, Andrew Hope, Ali Hosni, John Kim, Fei‐Fei Liu, C. Jillian Tsai, John N. Waldron, Anna Spreafico, Enrique Sanz‐Garcia, Lillian L. Siu, Tim Waterboer, Geoffrey Liu, Scott V. Bratman   +23 more
wiley   +1 more source

The plant microbiome: From ecological foundations to precision microbial engineering for sustainable agriculture

iMeta, EarlyView.
From ecological principles to precision engineering of plant microbiomes for sustainable agriculture. The plant holobiont integrates diverse microbial niches (including rhizosphere, endosphere, phyllosphere, seed, and aerial‐root mucilagesphere), host genetics (namely M genes), and host metabolites. Furthermore, molecular dialogues, including rhizobial
Mi Wei, Tengxiang Lian, Liying Chen, Lanxiang Wang, Junjie Ye, Xiaofang Yao, Shilong Duan, Ziyu Lu, Jinji Tu, Hongfu Li, Xin‐Yue Xu, Jie Zhou, Junliang He, Feiying Zhu, Paola Bonfante, Lam‐Son Phan Tran, Zhiqiang Pang, Xin Zhou, Zhihui Xu, Lin Zhang, Mengcen Wang, Xiaolin Wang, Chang‐Fu Tian, Yong‐Xin Liu, Kai Sun, Ertao Wang, Xianan Xie   +26 more
wiley   +1 more source

Tomato I2 Immune Receptor Can Be Engineered to Confer Partial Resistance to the Oomycete Phytophthora infestans in Addition to the Fungus Fusarium oxysporum

Molecular Plant-Microbe Interactions, 2015
Plants and animals rely on immune receptors, known as nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins, to defend against invading pathogens and activate immune responses.
Artemis Giannakopoulou, John F. C. Steele, Maria Eugenia Segretin, Tolga O. Bozkurt, Ji Zhou, Silke Robatzek, Mark J. Banfield, Marina Pais, Sophien Kamoun   +8 more
doaj   +1 more source

A New Paradigm: 46 Structural Cell Types Function as Environment‐Supporting Innate Immune Cells, With Endothelial and Vascular Smooth Muscle Cells as Key Prototypes

iNew Medicine, EarlyView.
ABSTRACT The scope, organization, and biological significance of innate immune functions across structural cell types remain poorly defined. To address these fundamental knowledge gaps, we analyzed experimental data of transcriptomes generated by our group and others.
Juanjuan Liu, Gayani K. Nanayakkara, Yifan Lu, Fatma Saaoud, Keman Xu, Ying Shao, Bo Yuan, Shih‐Yu Hung, Haiyan Xiang, Xianwei Wang, Sadia Mohsin, Sheng Wu, Xiaolei Liu, Juncheng Wei, Zhengjie Zhou, Beata Kosmider, Mingui Fu, Laisel Martinez, Roberto Vazquez‐Padron, Wenhui Hu, Shuping Ge, Hong Wang, Xiaofeng Yang   +22 more
wiley   +1 more source

The dynamic TaRACK1B-TaSGT1-TaHSP90 complex modulates NLR-protein-mediated antiviral immunity in wheat

Cell Reports
Summary: Nucleotide-binding leucine-rich repeat (NLR) proteins contribute widely to plant immunity by regulating defense mechanisms through the elicitation of a hypersensitive response (HR).
Haichao Hu, Tianye Zhang, Jinnan Wang, Jun Guo, Yaoyao Jiang, Qiansheng Liao, Lu Chen, Qisen Lu, Peng Liu, Kaili Zhong, Jiaqian Liu, Jianping Chen, Jian Yang   +12 more
doaj   +1 more source

A New Diagnostic Approach Using the NLR/LMR Ratio in the Differential Diagnosis of Neck Masses: Hematologic Evaluation of Patients With Cervical Lymphadenopathy

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates complete blood count–derived inflammatory ratios for differentiating lymphoma from benign cervical lymphadenopathies. The novel NLR/LMR ratio demonstrated superior diagnostic performance (AUC = 0.71, OR = 4.6) compared with conventional indices.
Servet Erdemes, Gizem Ay Haldız, Müslüm Ayral, Ali Çetin   +3 more
wiley   +1 more source

Hematological Inflammation Indices Are Associated With Active Uveitis in Ankylosing Spondylitis

Journal of Clinical Laboratory Analysis, EarlyView.
Hematological inflammation indices reflect the systemic inflammatory burden in ankylosing spondylitis. Patients with active uveitis exhibit a distinct pro‐inflammatory profile characterised by increased NLR, PLR, SII, SIRI, and AISI, along with decreased HALP and CALLY scores.
Mesude Seda Aydoğdu, Zarife Ekici Gök
wiley   +1 more source

Cell autonomous and non-autonomous functions of plant intracellular immune receptors in stomatal defense and apoplastic defense.

PLoS Pathogens, 2019
Stomatal closure defense and apoplastic defense are two major immunity mechanisms restricting the entry and propagation of microbe pathogens in plants. Surprisingly, activation of plant intracellular immune receptor NLR genes, while enhancing whole plant
Jiapei Yan, Huiyun Yu, Bo Li, Anqi Fan, Jeffrey Melkonian, Xiue Wang, Tong Zhou, Jian Hua   +7 more
doaj   +1 more source