Results 281 to 290 of about 98,851 (337)
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo +11 more
wiley +1 more source
The NGS and PCR-based Detection of EGFR Mutations in Liquid Biopsy: A Systematic Review and Meta-analysis Compared With Tissue Biopsy in Treatment-naïve Patients With Non-small Cell Lung Cancer. [PDF]
Molina MDSG +3 more
europepmc +1 more source
Oxidative Stress: Molecular Mechanisms, Diseases, and Therapeutic Targets
Oxidative stress occurs when the reactive oxygen species (ROS) production overwhelms the ROS scavenging, which lead to genomic instability, epigenetic regulation, proteostasis imbalance, and lipid peroxidation, subsequently causing the occurrence and development of numerous diseases. ABSTRACT Although the physiological level of reactive oxygen species (
Yi Qin +10 more
wiley +1 more source
Genome-wide identification and evolutionary analysis of disease resistance genes in Brassica carinata. [PDF]
Amas JC +7 more
europepmc +1 more source
Inflammation and Cancer: Molecular Mechanisms and Therapeutic Targets
Chronic inflammation fuels tumorigenesis via “internal drivers” and “external attractions.” Targeting these core mechanisms with combined therapies/novel deliveries enables precise, potent anti‐inflammatory–antitumor treatment. ABSTRACT Inflammation is a core pathological factor regulating tumor initiation, progression, and therapeutic resistance, and ...
Xiaodie Liu +4 more
wiley +1 more source
From Inflammation to Bone Loss: The Multifaceted Role of Neutrophils in Osteoporosis. [PDF]
Cheng H, Cheng Y, Wang G, Wang D, Liu X.
europepmc +1 more source
ABSTRACT The treatment of migraine is hampered by inter‐individual variability, leading to an inefficient “trial and error” approach. Artificial intelligence (AI) and machine learning (ML) offer a path towards precision medicine by predicting therapeutic outcomes.
Martina Giacon, Salvatore Terrazzino
wiley +1 more source
A Study of the Association of Cerebrospinal Fluid Neutrophil-to-Lymphocyte Ratio with Severity and Mortality in Patients with Tuberculous Meningitis. [PDF]
Mateen S +4 more
europepmc +1 more source
ABSTRACT Background Clozapine initiation often triggers inflammatory responses that can alter metabolism via Cytochrome P450 1A2 (CYP1A2) suppression. Although C‐reactive protein (CRP) is the recommended marker, it may be unavailable in community settings.
Nicoline Bihelek +3 more
wiley +1 more source

