Results 21 to 30 of about 86,244 (257)
A novel conserved mechanism for plant NLR protein pairs: the ‘integrated decoy’ hypothesis
Frontiers in Plant Science, 2014 Plant immunity is often triggered by the specific recognition of pathogen effectors by intracellular nucleotide-binding, leucine-rich repeat (NLR) receptors.
Stella ecesari +5 more
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Neutrophil-lymphocyte ratio as prognostic factor in metastatic breast cancer [PDF]
Revista Brasileira de Ginecologia e ObstetríciaObjective: The aim of the study was to analyze the role of the neutrophil to lymphocyte ratio (NLR) as a prognostic factor in metastatic breast cancer (MBC).
Gustavo Motta Cabello dos Santos +7 more
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PLoS Biology, 2021 In plants, nucleotide-binding domain and leucine-rich repeat (NLR)-containing proteins can form receptor networks to confer hypersensitive cell death and innate immunity.
Lida Derevnina +15 more
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Current Opinion in Plant Biology, 2021 Recent progress in large-scale sequencing, genomics, and rapid gene isolation techniques has accelerated the identification of race-specific resistance (R) genes and their corresponding avirulence (Avr) genes in wheat, barley, rye, and their wild relatives.
Sánchez-Martín, Javier, Keller, Beat
openaire +2 more sources
PLoS ONE, 2020 Plant NLR immune receptors are multidomain proteins that can function as specialized sensor/helper pairs. Paired NLR immune receptors are generally thought to function via negative regulation, where one NLR represses the activity of the second and ...
Rafał Zdrzałek +4 more
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Toll-Like Receptors (TLRs), NOD-Like Receptors (NLRs), and RIG-I-Like Receptors (RLRs) in Innate Immunity. TLRs, NLRs, and RLRs Ligands as Immunotherapeutic Agents for Hematopoietic Diseases [PDF]
International Journal of Molecular Sciences, 2021 The innate immune system plays a pivotal role in the first line of host defense against infections and is equipped with patterns recognition receptors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs).
Katarzyna Wicherska-Pawłowska +2 more
openaire +3 more sources
eLife, 2017 Plant immunity is tightly regulated to ensure proper defense against surrounding microbial pathogens without triggering autoimmunity, which negatively impacts plant growth and development.
Zhongshou Wu +5 more
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Frontiers in Cellular and Infection Microbiology, 2021 Anaplasma phagocytophilum is a tick-transmitted obligate intracellular Gram-negative bacterium that replicates in neutrophils. It elicits febrile disease in humans and in animals. In a mouse model, elimination of A. phagocytophilum required CD4+ T cells,
Beate J. Müller +7 more
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Nature Communications, 2018 Genes that confer resistance to plant pathogens such as rice blast disease typically encode NLR-type receptor proteins. Here, Zhao et al. describe a new resistance locus that encodes a non-NLR Armadillo repeat protein required for broad-spectrum ...
Haijun Zhao +12 more
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A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant. [PDF]
PLoS Genetics, 2015 During exocytosis, the evolutionarily conserved exocyst complex tethers Golgi-derived vesicles to the target plasma membrane, a critical function for secretory pathways.
Ting Zhao +9 more
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