Results 31 to 40 of about 1,342,871 (301)

A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant. [PDF]

PLoS Genetics, 2015
During exocytosis, the evolutionarily conserved exocyst complex tethers Golgi-derived vesicles to the target plasma membrane, a critical function for secretory pathways.
Ting Zhao, Lu Rui, Juan Li, Marc T Nishimura, John P Vogel, Na Liu, Simu Liu, Yaofei Zhao, Jeffery L Dangl, Dingzhong Tang   +9 more
doaj   +1 more source

The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance

Nature Communications, 2018
Genes that confer resistance to plant pathogens such as rice blast disease typically encode NLR-type receptor proteins. Here, Zhao et al. describe a new resistance locus that encodes a non-NLR Armadillo repeat protein required for broad-spectrum ...
Haijun Zhao, Xueyan Wang, Yulin Jia, Bastian Minkenberg, Matthew Wheatley, Jiangbo Fan, Melissa H. Jia, Adam Famoso, Jeremy D. Edwards, Yeshi Wamishe, Barbara Valent, Guo-Liang Wang, Yinong Yang   +12 more
doaj   +1 more source

The NLR-Annotator Tool Enables Annotation of the Intracellular Immune Receptor Repertoire [PDF]

Plant Physiology, 2020
Disease resistance genes encoding nucleotide-binding and leucine-rich repeat (NLR) intracellular immune receptor proteins detect pathogens by the presence of pathogen effectors. Plant genomes typically contain hundreds of NLR-encoding genes. The availability of the hexaploid wheat (Triticum aestivum) cultivar Chinese Spring reference genome allows a ...
Steuernagel, Burkhard, Witek, Kamil, Krattinger, Simon G, Ramirez-Gonzalez, Ricardo H, Schoonbeek, Henk-jan, Yu, Guotai, Baggs, Erin, Witek, Agnieszka I, Yadav, Inderjit, Krasileva, Ksenia V, Jones, Jonathan D G, Uauy, Cristobal, Keller, Beat, Ridout, Christopher J, Wulff, Brande B H   +14 more
openaire   +5 more sources

Association Between Neutrophil-Lymphocyte Ratio and Oncotype Dx Recurrence Score in Early-Stage Hormonal Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer

Cancer Management and Research, 2021
Bader Alshamsan,1,2 Aisha Alshibany,1 Mahmoud A Elshenawy,1,3 Ahmed Badran,1,4 Tusneem Elhassan,1 Dahish Ajarim,1 Adher Alsayed,1 Kausar Suleman,1 Taher Al-Tweigeri1 1Medical Oncology, Oncology Center, King Faisal Specialist Hospital & Research Centre ...
Alshamsan B, Alshibany A, Elshenawy MA, Badran A, Elhassan T, Ajarim D, Alsayed A, Suleman K, Al-Tweigeri T   +8 more
doaj  

Effects of Primary Tumor Resection on Metastatic Breast Cancer Survival and the Predictive Power of Neutrophil: Lymphocyte Ratio on Prognosis

European Journal of Breast Health, 2021
Objective:The aim was to investigate the effect of primary tumor resection (PTR) on survival in metastatic breast cancer patients and to assess the power of the neutrophil-to-lymphocyte ratio (NLR) regarding the prediction of prognosis in this patient ...
Yaşar Çöpelci, Umut Rıza Gündüz, Bülent Dinç, Nurhan Haluk Belen, Şeyda Gündüz   +4 more
doaj   +1 more source

The BTB/POZ-MATH Protein ZmBPM1 Interacts With Autophagy-related Protein ZmATG6 and Modulates the NLR Protein Rp1-D21-Mediated Defense Response in Maize. [PDF]

Adv Sci (Weinh)
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Tang CX, Liu TT, Ge QD, Liu XY, Wang W, Sun Y, Liu Y, Li F, Wang GF.   +8 more
europepmc   +2 more sources

Uncovering the repertoire of legume NLR immune receptors

, 2022
The legume family (Fabaceae) is the third-largest angiosperm family and is considered one of the most important crop families. Biotic stress constrains legume yield, and resistance breeding is currently considered the most sustainable management method to deal with pathogen pressure in the field.
Marques, Rita Maravilha, Santos, Carmen, Patto, Carlota Vaz, Kamoun, Sophien, Kourelis, Jiorgos   +4 more
openaire   +2 more sources

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

Communications Biology, 2022
This review discusses emerging roles for the NLR family pyrin domain containing 6 receptor (NLRP6) in intestinal homeostasis, inflammation, cancer, the nervous system and liver disease.
Diego Angosto-Bazarra, Cristina Molina-López, Pablo Pelegrín   +2 more
doaj   +1 more source

Protein-protein interactions in the RPS4/RRS1 immune receptor complex.

PLoS Pathogens, 2017
Plant NLR (Nucleotide-binding domain and Leucine-rich Repeat) immune receptor proteins are encoded by Resistance (R) genes and confer specific resistance to pathogen races that carry the corresponding recognized effectors.
Sung Un Huh, Volkan Cevik, Pingtao Ding, Zane Duxbury, Yan Ma, Laurence Tomlinson, Panagiotis F Sarris, Jonathan D G Jones   +7 more
doaj   +1 more source

The allelic rice immune receptor Pikh confers extended resistance to strains of the blast fungus through a single polymorphism in the effector binding interface.

PLoS Pathogens, 2021
Arms race co-evolution drives rapid adaptive changes in pathogens and in the immune systems of their hosts. Plant intracellular NLR immune receptors detect effectors delivered by pathogens to promote susceptibility, activating an immune response that ...
Juan Carlos De la Concepcion, Josephine H R Maidment, Apinya Longya, Gui Xiao, Marina Franceschetti, Mark J Banfield   +5 more
doaj   +1 more source