Results 31 to 40 of about 82,639 (162)

Regulation of plant immune receptor accumulation through translational repression by a glycine-tyrosine-phenylalanine (GYF) domain protein

eLife, 2017
Plant immunity is tightly regulated to ensure proper defense against surrounding microbial pathogens without triggering autoimmunity, which negatively impacts plant growth and development.
Zhongshou Wu, Shuai Huang, Xiaobo Zhang, Di Wu, Shitou Xia, Xin Li   +5 more
doaj   +1 more source

A truncated NLR protein, TIR-NBS2, is required for activated defense responses in the exo70B1 mutant. [PDF]

PLoS Genetics, 2015
During exocytosis, the evolutionarily conserved exocyst complex tethers Golgi-derived vesicles to the target plasma membrane, a critical function for secretory pathways.
Ting Zhao, Lu Rui, Juan Li, Marc T Nishimura, John P Vogel, Na Liu, Simu Liu, Yaofei Zhao, Jeffery L Dangl, Dingzhong Tang   +9 more
doaj   +1 more source

The rice blast resistance gene Ptr encodes an atypical protein required for broad-spectrum disease resistance

Nature Communications, 2018
Genes that confer resistance to plant pathogens such as rice blast disease typically encode NLR-type receptor proteins. Here, Zhao et al. describe a new resistance locus that encodes a non-NLR Armadillo repeat protein required for broad-spectrum ...
Haijun Zhao, Xueyan Wang, Yulin Jia, Bastian Minkenberg, Matthew Wheatley, Jiangbo Fan, Melissa H. Jia, Adam Famoso, Jeremy D. Edwards, Yeshi Wamishe, Barbara Valent, Guo-Liang Wang, Yinong Yang   +12 more
doaj   +1 more source

The new era of bioengineered plant NLR receptors. [PDF]

Plant Commun
Cao P, Sun Z, Wang S, Zhang Q, An Y, Zhang M.   +5 more
europepmc   +2 more sources

NLR receptors in plant immunity: making sense of the alphabet soup

EMBO reports, 2023
AbstractPlants coordinately use cell‐surface and intracellular immune receptors to perceive pathogens and mount an immune response. Intracellular events of pathogen recognition are largely mediated by immune receptors of the nucleotide binding and leucine rich‐repeat (NLR) classes.
Contreras, Mauricio P., Lüdke, Daniel, Pai, Hsuan, Toghani, AmirAli, Kamoun, Sophien   +4 more
openaire   +4 more sources

Association Between Neutrophil-Lymphocyte Ratio and Oncotype Dx Recurrence Score in Early-Stage Hormonal Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer

Cancer Management and Research, 2021
Bader Alshamsan,1,2 Aisha Alshibany,1 Mahmoud A Elshenawy,1,3 Ahmed Badran,1,4 Tusneem Elhassan,1 Dahish Ajarim,1 Adher Alsayed,1 Kausar Suleman,1 Taher Al-Tweigeri1 1Medical Oncology, Oncology Center, King Faisal Specialist Hospital & Research Centre ...
Alshamsan B, Alshibany A, Elshenawy MA, Badran A, Elhassan T, Ajarim D, Alsayed A, Suleman K, Al-Tweigeri T   +8 more
doaj  

The allelic rice immune receptor Pikh confers extended resistance to strains of the blast fungus through a single polymorphism in the effector binding interface.

PLoS Pathogens, 2021
Arms race co-evolution drives rapid adaptive changes in pathogens and in the immune systems of their hosts. Plant intracellular NLR immune receptors detect effectors delivered by pathogens to promote susceptibility, activating an immune response that ...
Juan Carlos De la Concepcion, Josephine H R Maidment, Apinya Longya, Gui Xiao, Marina Franceschetti, Mark J Banfield   +5 more
doaj   +1 more source

Effects of Primary Tumor Resection on Metastatic Breast Cancer Survival and the Predictive Power of Neutrophil: Lymphocyte Ratio on Prognosis

European Journal of Breast Health, 2021
Objective:The aim was to investigate the effect of primary tumor resection (PTR) on survival in metastatic breast cancer patients and to assess the power of the neutrophil-to-lymphocyte ratio (NLR) regarding the prediction of prognosis in this patient ...
Yaşar Çöpelci, Umut Rıza Gündüz, Bülent Dinç, Nurhan Haluk Belen, Şeyda Gündüz   +4 more
doaj   +1 more source

Uncovering the repertoire of legume NLR immune receptors

, 2022
The legume family (Fabaceae) is the third-largest angiosperm family and is considered one of the most important crop families. Biotic stress constrains legume yield, and resistance breeding is currently considered the most sustainable management method to deal with pathogen pressure in the field.
Marques, Rita Maravilha, Santos, Carmen, Patto, Carlota Vaz, Kamoun, Sophien, Kourelis, Jiorgos   +4 more
openaire   +1 more source

Physiological and pathophysiological functions of NLRP6: pro- and anti-inflammatory roles

Communications Biology, 2022
This review discusses emerging roles for the NLR family pyrin domain containing 6 receptor (NLRP6) in intestinal homeostasis, inflammation, cancer, the nervous system and liver disease.
Diego Angosto-Bazarra, Cristina Molina-López, Pablo Pelegrín   +2 more
doaj   +1 more source