Results 211 to 220 of about 135,752 (336)

Sulphonylureas as Adjunct Therapeutic Agents in the Treatment of Autoimmune Conditions: A Narrative Review. [PDF]

Pharmacol Res Perspect
Elford J, O'Reilly RJ, Babey AM, Rafeek RAM, Ketheesan N.   +4 more
europepmc   +1 more source

W1785 Loss of NLRP3 Signaling Results in Altered Dendritic Cells (DC) Population and Impaired Induction of Regulatory T Cells (Treg): Implications for Intestinal Inflammation

, 2010
Aito Ueno, Simon A. Hirota, Jeff Ng, Yan Li, Daniel A. Muruve, Jürg Tschopp, Paul L. Beck, Subrata Ghosh   +7 more
openalex   +1 more source

Gout and NLRP3 Inflammasome Biology

Arthritis &Rheumatology, EarlyView.
This review describes the three broad stages of acute inflammation in the context of gout: initiation, leucocyte mobilization, and self‐resolution. A typical case of a gout flare is presented. The role of the NLRP3 inflammasome in acute monosodium urate crystal–induced inflammation is reviewed in detail.
Raewyn Poulsen, Nicola Dalbeth
wiley   +1 more source

Unleashing the potential of exercise: conquering cardiovascular disease by targeting inflammasome activation. [PDF]

Eur J Med Res
Xiang L, Su Z.
europepmc   +1 more source

687 Loss of the NOD2-Related Molecule NLRP3 Results in Broad Changes in the Innate Immune Response and Intestinal Microbiota Resulting in an Increased Susceptibility to Intestinal Inflammation

, 2010
Simon A. Hirota, Jeff Ng, Maitham A. Khajah, Yan Li, Victor L. Lam, Kevin P. Rioux, Jürg Tschopp, Donna‐Marie McCafferty, Daniel A. Muruve, Justin A. MacDonald, Paul L. Beck   +10 more
openalex   +1 more source

Monocyte‐derived macrophages‐synovial fibroblasts crosstalk unravels oncostatin signaling network as a driver of synovitis in osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Osteoarthritis (OA) is a debilitating joint disease characterized by cartilage degradation, synovial inflammation, and pain. Macrophages have been implicated in OA pathology, but the origins and functions of diverse macrophage subsets seeding the synovial joint tissue remain incompletely understood.
Damien Laouteouet, Olivier Bortolotti, Léa Marineche, Nicole Hannemann, Manon Chambon, Yaël Glasson, Anne‐Sophie Dumé, Julien De Lima, Maud Fournial, Dylan Touchet, Dany Séverac, Felicia Leccia, Christophe Duperray, Henri‐Alexandre Michaud, Farida Djouad, Benoît Le Goff, Frédéric Blanchard, Florence Apparailly, Gabriel Courties   +18 more
wiley   +1 more source

The NLRP3 inflammasome in urogenital cancers: structure, dual function, and therapeutic potential. [PDF]

Front Oncol
Sun W, Ma R, Zhao R, Tian J, Liu W.
europepmc   +1 more source

Alu Overexpression Leads to an Increased Double‐stranded RNA Signature in Dermatomyositis

Arthritis &Rheumatology, Accepted Article.
Objective Dermatomyositis is an autoimmune condition characterized by a high interferon signature of unknown etiology. Because coding sequences constitute <1.2% of our genomes, there is a need to explore the role of the non‐coding genome in disease pathogenesis.
Rayan Najjar, Andrew Mammen, Tomas Mustelin   +2 more
wiley   +1 more source

Correction: Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation. [PDF]

Hepatol Int
Feng S, Xie X, Li J, Xu X, Chen C, Zou G, Lin G, Huang T, Hu R, Ran T, Han L, Zhang Q, Li Y, Zhao X.   +13 more
europepmc   +1 more source

Faculty Opinions recommendation of Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes.

, 2010
Steve Ward
openalex   +2 more sources