Results 101 to 110 of about 61,577 (309)

The interactions between the Trn1 and the FUS-NLS.

, 2012
(A) Summary of the polar/electrostatic interactions between FUS-NLS (yellow) and Trn1 (cyan). FUS-NLS is divided into region I (E523–Y526), region II (D512–R522), and region III (P508–M511).
Liuqing Yang (128705), Chunyan Niu (128700), Jiayu Zhang (128702), Feng Gao (3548), Weimin Gong (120989), Minze Jia (128708), Haining Zhu (128711)   +6 more
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Palatable‐Food–Driven Top‐Down Circuit Inhibits PVNCRF Activity to Mitigate Stress Via Peri‐PVNCRFR1 Neurons

Advanced Science, EarlyView.
Palatable food alleviates stress and prevents anxiety. This study uncovers a dedicated neural pathway: dopamine release in the PFC activates D1R neurons, whose projections to the peri‐PVN engage a population of anxiolytic CRFR1 neurons. These neurons then inhibit stress‐induced hyperactivity of PVNCRF neurons, providing a circuit‐level explanation for ...
Yuchuan Hong, Shirui Jun, Tianjiao Deng, Gaojie Shao, Dan Liu, Yi Sun, Yan Chen, Qian Xiao, Jie Shao, Sheng Wang, Tianwen Huang, Fan Yang, Jie Tu   +12 more
wiley   +1 more source

Subcellular localization of unconventional NLS mutants.

, 2013
(A) Schematic diagram and subcellular localization of the N-terminal 110-amino acid region (NP110aa) NLS mutants. The unconventional NLS (aa 3-TKGTKRSYEQM-13), overlapping bipartite NLS (aa 90-KKTGGPIYRRVDGKWRRELILYDKEEIRRIWR-121) or bipartite NLS (aa ...
Yutaka Sasaki (286423), Kazunori Yamada (286428), Kyoji Hagiwara (286424), Yoko Aida (179321), Michinori Kakisaka (286426), Tomoyuki Murakami (195979)   +5 more
core   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Genomic fragments from high copy screen suppress Htt103Q-NLS toxicity.

, 2014
(A) Genomic fragments (GF) 1 through 12 suppress Htt103Q-NLS toxicity as monitored by growth assay plated in 5-fold dilutions on galactose containing media. (B) Impact of GF1-12 upon Htt103Q-NLS expression levels as monitored by Western blot.
Douglas M. Cyr (102586), Hong Yu Ren (102585), Katie J. Wolfe (102584), Philipp Trepte (564084)   +3 more
core   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Dynamic soliton solutions of NLS type equation

, 2016
The topic of these thesis is the study of different types of the Nonlinear Schrodinger Equation(NLS), like Gross-Pitaevskii and modified NLS with the present of weak nonlocality. Our study are based to analytical methods.
Μυλωνάς, Ιωάννης, Mylonas, Ioannis   +1 more
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A Symmetric Cogeneration Fuel Cell for Coupled Production of Hydrogen, Ammonia and Formate

Advanced Science, EarlyView.
A symmetric cogeneration fuel cell integrating value‐added chemical synthesis with electricity generation by coupling formaldehyde oxidation with the nitrate reduction was developed. This work highlights the broader potential of symmetric cogeneration fuel cells as a general platform for rational reaction pairing, offering a practical pathway to lower ...
Yingjie Song, Peimiao Zou, Renhang Wang, Qi Zhang, Yisong Han, Christopher Waldron, Marc Walker, Ben G. Breeze, Shanwen Tao   +8 more
wiley   +1 more source

Employer Provided Pension Data in the NLS Mature Women's Survey and in the Health and Retirement Study [PDF]

We compute pension wealth from employer provided pension plan descriptions matched to respondent surveys to the National Longitudinal Survey of Mature Women (NLS-MW) and the Health and Retirement Study (HRS).
Alan L. Gustman, Thomas L. Steinmeier
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NLS business law review.

, 2021
The NLS business law review is the oldest and leading national academic publication on business and corporate laws in India. The NLS business law review intends to recognize and foster academic research and scholarship in commercial law by examining the ...

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