Results 211 to 220 of about 157,319 (379)
Polymeric Giant Unilamellar Vesicles Support Longevity of Native Nuclei in Protocells
Small Science, EarlyView.Native nuclei are isolated and incorporated into polymeric giant unilamellar vesicles (pGUVs) using microfluidics. Nucleated pGUVs retain nuclear integrity and function, providing a new platform to study the import process of peptide‐based multicompartment micelles via nuclear localization signals. This bottom‐up chimeric system lays the groundwork for
Lukas Heuberger +7 more
wiley +1 more source
A Chemogenetic Toolkit for Inducible, Cell Type‐Specific Actin Disassembly
Small Methods, EarlyView.ChiActs are novel actin‐perturbing genetic tools that can be rapidly activated by chemical actuators and optogenetically targeted to distinct subcellular locations using light. ChiActs rapidly induce actin disassembly in several model cell types and are able to perturb actin‐dependent nano‐assembly and cellular functions, including inhibition of ...
Tien‐Hung Lan +5 more
wiley +1 more source
111In-Labeled Trastuzumab (Herceptin) Modified with Nuclear Localization Sequences (NLS): An Auger Electron-Emitting Radiotherapeutic Agent for HER2/neu-Amplified Breast Cancer [PDF]
, 2007 D. L. Costantini +4 more
openalex +1 more source
FASEB BioAdvances, Volume 7, Issue 4, April 2025.This study developed an Rbfox3‐iCre knock‐in mouse model to explore Cre‐loxP‐based genetic recombination. Gene recombination was observed in the central nervous system and heart during embryonic development and in neurons, but not glial or NeuN‐negative neural cells, in the adult brain.
Shiho Nishino +8 more
wiley +1 more source
Gender &History, EarlyView.Abstract This article uses rare and detailed data on matriculants to the University of Oxford during the middle decades of the twentieth century as a prism through which to consider gendered processes of recruitment to elite institutions. The article makes four key claims. First, the broader shifts in middle‐class women's labour market participation in
Eve Worth, Naomi Muggleton, Aaron Reeves
wiley +1 more source
The transformer gene controls sexual development in Drosophila suzukii
Insect Science, EarlyView.The transformer gene plays a key role in the genetic pathway for sexual development in Drosophila suzukii Abstract The genetic network of sex determination in the model organism Drosophila melanogaster was investigated in great detail. Such knowledge not only advances our understanding of the evolution and regulation of sexual dimorphism in insects ...
Ying Yan +8 more
wiley +1 more source
Annals of Applied Biology, EarlyView.Unveiling Bonelli's Eagle nestling growth rates. Abstract Understanding the growth rate of nestlings is essential for explaining developmental strategies and is particularly important for birds of prey. Given that they have lower reproduction rates than other species, the growth rate could be one of the critical factors determining parental fitness and
Savvas Iezekiel +4 more
wiley +1 more source
Andrology, EarlyView.Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos +4 more
wiley +1 more source