Results 41 to 50 of about 3,123 (185)

Clinical significance of serum NM23‐H1 protein in neuroblastoma [PDF]

Cancer Science, 2005
We have previously reported that NM23 genes are overexpressed in various hematological malignancies and that serum NM23‐H1 protein levels are useful for predicting patient outcomes. In this study we assessed the clinical implications of serum NM23‐H1 protein on neuroblastoma.
Junko, Okabe-Kado, Takashi, Kasukabe, Yoshio, Honma, Ryoji, Hanada, Akira, Nakagawara, Yasuhiko, Kaneko   +5 more
openaire   +2 more sources

The centrosomal kinase Aurora-A/STK15 interacts with a putative tumor suppressor NM23-H1 [PDF]

, 2002
Alterations in the activity of the centrosomal kinase, Aurora-A/STK15, have been implicated in centrosome amplification, genome instability and cellular transformation. How STK15 participates in all of these processes remains largely mysterious.
Du, J., Hannon, G. J.
core   +1 more source

Expression of nm23-H1 gene product in esophageal squamous cell carcinoma and its association with vessel invasion and survival

BMC Cancer, 2001
Background We assessed the nm23-H1 gene product expression and its relationship with lymphatic and blood vessel invasion in patients with esophageal squamous cell carcinoma.
Shimizu Tetsuya, Maeda Masayuki, Edagawa Masao, Matsuzaki Yasunori, Ayabe Takanori, Tomita Masaki, Hara Masaki, Onitsuka Toshio   +7 more
doaj   +1 more source

Transactivation potential of the C‐terminus of human Nm23‐H1 [PDF]

FEBS Letters, 1998
The transactivation potential of Nm23‐H1, a homolog ofc‐myctranscription factor Nm23‐H2/PuF was assessed in yeast as a fusion protein with the DNA binding domains (DBDs) of GAL4 and LexA. The C‐terminal half of Nm23‐H1 exhibited strong transactivation of the reporter genes,LacZandLeu2carrying GAL4 and LexA upstream activating sequences (UASs), whereas ...
Chae, Suhn-Kee, Lee, Nam-Sihk, Lee, Kong-Joo, Kim, Eunhee   +3 more
openaire   +2 more sources

Alcohol promotes breast cancer cell invasion by regulating the Nm23-ITGA5 pathway [PDF]

, 2011
Background Alcohol consumption is an established risk factor for breast cancer metastasis. Yet, the mechanism by which alcohol promotes breast cancer metastases is unknown.
Amy W Wong, Qiwei X Paulson, Jina Hong, Renee E Stubbins, Karen Poh, Emily Schrader, Nomeli P Nunez   +6 more
core   +1 more source

Lentivirus-mediated Stable Silencing of nm23-H1 Gene in Lung Cancer Cells 
and the Influence on Biological Behavior

Chinese Journal of Lung Cancer, 2012
Background and objective The nm23-H1 gene is an important tumor metastatic suppressor gene. Our previous study showed that the downregulation of nm23-H1 gene expression using small interfering RNA (siRNA) in NL9980 lung cancer cells greatly enhanced ...
Meng LUO, Daxing ZHU, Lei GONG, Xiaoming QIU, Lingling ZU, Liya SUN, Zhihao WU, Qinghua ZHOU   +7 more
doaj   +1 more source

Transcription analysis of TIMP-1 and NM23 genes in glioma cell invasion [PDF]

, 2004
Universidade Federal de São Paulo (UNIFESP) EPMUNIFESP ...
Santos, José Augusto Nasser dos
core   +4 more sources

The dosage-dependent effect exerted by the NM23-H1/H2 homolog NDK-1 on distal tip cell migration in C. elegans [PDF]

, 2018
Abnormal regulation of cell migration and altered rearrangement of the cytoskeleton are fundamental properties of metastatic cells. The first identified metastasis suppressor NM23-H1, which displays nucleoside-diphosphate kinase (NDPK) activity is ...
A Diwakar, A Harłozińska, A Leone, A Leone, A Yokoyama, Alexandra Gráf, AM Rosengard, Anil Mehta, C Baughman, CE Horak, CE Horak, CM Meighan, CR Dearolf, D Ma, DJ Montell, DL Silver, EH Postel, EJ Cram, F Liu, FN Van Leeuwen, G Nallamothu, GP Bell, H Baba, H Miyazaki, H Tagashira, I Andolfo, J Schottenfeld, JA McDonald, JA Woolworth, K Takács-Vellai, KAP Mitchell, Krisztina Takács-Vellai, Krisztián Tárnok, KS Krishnan, L Fancsalszky, Luca Fancsalszky, M Affolter, M Boissan, M Boissan, M Boissan, M Boissan, M Engel, M Fukuda, M Ilijas, M Murakami, M Tokarska-Schlattner, M-C Wong, M-Y Lee, MT Hartsough, N Marino, N Masoudi, P Duchek, PS Steeg, PS Steeg, Q Zhang, R Ferru-Clément, R Lehmann, RF Epand, RK Thakur, RS Parhar, S. Klumpp, SJ Annesley, T Desvignes, T Hsu, T Mochizuki, T Ouatas, U Schlattner, V Dammai, Y Otsuki, Y-T Tee, Z Fan, Zsolt Farkas, Éva Saskői   +72 more
core   +2 more sources

nm23-H1 expression in nasopharyngeal carcinoma: correlation with clinical outcome [PDF]

International Journal of Cancer, 1998
The expression levels of nm23-H1 mRNA and its protein in human nasopharyngeal carcinoma (NPC) were detected to clarify the relationship between nm23-H1 and metastasis and prognosis of patients with NPC. nm23-H1 mRNA expression in fresh tissues from 78 patients with NPC was investigated by in situ hybridization and RT-PCR.
X, Guo, H Q, Min, M S, Zeng, C N, Qian, X M, Huang, J Y, Shao, J H, Hou   +6 more
openaire   +2 more sources

Functional Genomics of PRUNE1 in Neurodevelopmental Disorders (NDDs) Tied to Medulloblastoma (MB) and Other Tumors

Frontiers in Oncology, 2021
We analyze the fundamental functions of Prune_1 in brain pathophysiology. We discuss the importance and maintenance of the function of Prune_1 and how its perturbation influences both brain pathological conditions, neurodevelopmental disorder with ...
Francesca Bibbò, Francesca Bibbò, Carmen Sorice, Carmen Sorice, Veronica Ferrucci, Veronica Ferrucci, Massimo Zollo, Massimo Zollo   +7 more
doaj   +1 more source