Transcription analysis of TIMP-1 and NM23 genes in glioma cell invasion [PDF]
, 2004 Universidade Federal de São Paulo (UNIFESP) EPMUNIFESP ...
Santos, José Augusto Nasser dos
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The NM23-H1/H2 homolog NDK-1 is required for full activation of Ras signaling in C. elegans [PDF]
, 2013 The group I members of the Nm23 (non-metastatic) gene family encode nucleoside diphosphate kinases (NDPKs) that have been implicated in the regulation of cell migration, proliferation and differentiation.
Abdus-Saboor +41 more
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Nm23‐H1 inhibits lung cancer bone‐specific metastasis by upregulating miR‐660‐5p targeted SMARCA5
Thoracic Cancer, Volume 11, Issue 3, Page 640-650, March 2020., 2020 Abstract Background Nm23‐H1 gene has been found to be an inhibitor of tumor metastasis in lung cancer. MicroRNAs (miRNAs) play key roles in tumor metastasis through multiple signaling pathways. This study explored whether the nm23‐H1 gene could inhibit invasion and metastasis of lung cancer cells by regulating miRNA‐660‐5p targets. Methods Quantitative
Cheng Ai +8 more
wiley +1 more source
The dosage-dependent effect exerted by the NM23-H1/H2 homolog NDK-1 on distal tip cell migration in C. elegans [PDF]
, 2018 Abnormal regulation of cell migration and altered rearrangement of the cytoskeleton are fundamental properties of metastatic cells. The first identified metastasis suppressor NM23-H1, which displays nucleoside-diphosphate kinase (NDPK) activity is ...
A Diwakar +72 more
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STRAD in Peutz-Jeghers syndrome and sporadic cancers [PDF]
, 2005 Background/Aims: LKB1 is a tumour suppressor gene that is associated with Peutz-Jeghers syndrome (PJS), a rare autosomal dominant cancer predisposition syndrome.
Leng, W.W. de +10 more
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Proteomics of AML1/ETO Target Proteins: AML1–ETO Targets a C/EBP–NM23 Pathway [PDF]
, 2010 Introduction The rational design of targeted therapies for acute myeloid leukemia (AML) requires the discovery of novel protein pathways in the systems biology of a specific AML subtype.
Arun Kumar Trivedi +5 more
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17beta-hydroxysteroid dehydrogenase type 1 modulates breast cancer protein profile and impacts cell migration [PDF]
, 2012 INTRODUCTION: Human 17beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) is a steroid-converting enzyme that has long been known to play critical roles in estradiol synthesis and more recently in dihydrotestosterone (DHT) inactivation, showing a dual ...
François Houle +4 more
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Strand-specific miR-28-5p and miR-28-3p have distinct effects in colorectal cancer cells [PDF]
, 2012 The authors thank Sue Moreau from the Department of Scientific Publications at The University of Texas MD Anderson Cancer Center for English language editing of the manuscript.
Almeida +54 more
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Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.ABSTRACT Chimeric antigen receptor T cell (CAR‐T) therapy has demonstrated remarkable efficacy in haematologic malignancies but remains constrained in solid tumours due to limited tumour penetration, immunosuppressive microenvironments and the risk of cytokine release syndrome (CRS).
Ruyue Yang +10 more
wiley +1 more source
A competitive cell-permeable peptide impairs Nme-1 (NDPK-A) and Prune-1 interaction: therapeutic applications in cancer. [PDF]
, 2018 The understanding of protein–protein interactions is crucial in order to generate a second level of functional genomic analysis in human disease. Within a cellular microenvironment, protein–protein interactions generate new functions that can be defined ...
Asadzadeh, F. +4 more
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