Multifaceted role of TREX2 in the skin defense against UV-induced skin carcinogenesis [PDF]
TREX2 is a 3'-DNA exonuclease specifically expressed in keratinocytes. Here, we investigated the relevance and mechanisms of TREX2 in ultraviolet (UV)-induced skin carcinogenesis. TREX2 expression was up-regulated by chronic UV exposure whereas it was de-
Benito, Carmen +17 more
core +1 more source
Receptor Activation Regulates Cortical, but not Vesicular Localization of NDP Kinase [PDF]
We used immunofluorescence techniques to determine the localization of nucleoside diphosphate (NDP) kinase in NIH-3T3 fibroblasts. We found that cytoplasmic NDP kinase can be separated into two populations according to subcellular localization and ...
Gallagher, Betty C. +3 more
core +1 more source
Expression of antimetastatic gene nm23-H1 in epithelial ovarian cancer.
To investigate the expression of nm23-H1 in epithelial ovarian cancer.A total of 55 specimens from patients with epithelial ovarian cancers, 15 patients with serous cancers, 7 with mucinous cancers, 17 with endometrioid cancers and 16 with adenocarcinomas, were examined for the expression of nm23-H1 by means of the immunohistochemical technique.The ...
M, Qian +4 more
openaire +1 more source
Nasopharyngeal carcinoma: molecular biomarker discovery and progress [PDF]
Nasopharyngeal carcinoma (NPC) is a rare malignancy in most part of the world and it is one of the most confusing, commonly misdiagnosed and poorly understood diseases.
Cho William
core +2 more sources
Abstract Book: 25th Congress of the European Hematology Association Virtual Edition, 2020
HemaSphere, Volume 4, Issue S1, Page 1-1168, June 2020.
wiley +1 more source
Cytosolic Trypanosoma cruzi nucleoside diphosphate kinase generates large granules that depend on its quaternary structure [PDF]
Nucleoside diphosphate kinase (NDPK) is a key enzyme in the control of cellular concentrations of nucleoside triphosphates, and has been shown to play important roles in many cellular processes.
Di Girolamo, Fabio Augusto +4 more
core +1 more source
Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer [PDF]
Background Previous studies identified the human nonmetastatic gene 23 (NME1, hereafter Nm23-H1) as the first metastasis suppressor gene. An inverse relationship between Nm23-H1 and expression of lysophosphatidic acid receptor 1 gene (LPAR1, also known ...
Albaugh, Mary +11 more
core
A case study - Regulation and Functional Mechanisms of Cancer Cells and Control its Activity Using Plants and their Derivatives [PDF]
Novel exploiting to the understanding of conventional medicine was followed by the findings of many unique secondary metabolites and its biological property and is highly required for treating of many endemic diseases.
Gaanty Pragas, Maniam +3 more
core +1 more source
Leukemia and small round blue-cell tumor cancer detection using microarray gene expression data set: Combining data dimension reduction and variable selection technique [PDF]
Using gene expression data in cancer classification plays an important role for solving the fundamental problems relating to cancer diagnosis. Because of high throughput of gene expression data for healthy and patient samples, a variable selection ...
Farrokhnia, Maryam, Karimi, Sadegh
core

