Neuronal surface and intracellular antibody testing in patients with long‐term epilepsy
Epilepsia Open, EarlyView.Abstract Objective We aimed to investigate the frequency of neuronal surface and intracellular antibodies in individuals with long‐term epilepsy and the associated clinical and laboratory characteristics. Methods We tested sera from 223 patients with epilepsy without signs of autoimmune encephalitis and 12 patients with epilepsy and a subacute onset of
Nancy Watanabe +9 more
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Neuronal oxidative injury in the development of the epileptic disease : a potential target for novel therapeutic approaches [PDF]
, 2011 Epileptic diseases affect about 50 million people in the world and approximately 30% of patients diagnosed with epilepsy are unresponsive to current medications.
Maio, Roberto di
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Erratum: Corrigendum: NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones [PDF]
, 1986 Amy B. MacDermott +4 more
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The GluN3-containing NMDA receptors
ChannelsN-methyl-D-aspartate receptors (NMDARs) are heterotetrameric ion channels that play crucial roles in brain function. Among all the NMDAR subtypes, GluN1-N3 receptors exhibit unique agonist binding and gating properties. Unlike "conventional" GluN1-N2 receptors, which require both glycine and glutamate for activation, GluN1-N3 receptors are activated ...
Kunlong Xiong +4 more
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Epilepsy and systemic autoimmune diseases: A bidirectional two‐sample Mendelian randomization study
Epilepsia Open, EarlyView.Abstract Objective Epidemiological data indicates that individuals with epilepsy exhibit an elevated susceptibility to autoimmune disorders, and conversely, those with systemic autoimmune diseases (SAD) demonstrate a heightened predisposition to epilepsy.
Ruoshi Tian +4 more
wiley +1 more source
D₂ Dopamine Receptors Colocalize Regulator of G-Protein Signaling 9-2 (RGS9-2) via the RGS9 DEP Domain, and RGS9 Knock-Out Mice Develop Dyskinesias Associated with Dopamine Pathways [PDF]
, 2005 Regulator of G-protein signaling 9-2 (RGS9-2), a member of the RGS family of Gα GTPase accelerating proteins, is expressed specifically in the striatum, which participates in antipsychotic-induced tardive dyskinesia and in levodopa-induced dyskinesia. We
Axelrod, Jeffrey D. +10 more
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Food Frontiers, EarlyView.LPSP exhibited considerable potential in reversing OTC‐induced anxiety‐like behavior. Combined with gut microbiomics and metabolomics, we revealed the underlying mechanisms. ABSTRACT The use of oxytetracycline (OTC) in aquaculture is crucial for fish health and disease prevention, but it might accumulate in humans through the food chain, potentially ...
Yang Qiu +6 more
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Interactions between the glycine and glutamate binding sites of the NMDA receptor [PDF]
, 1993 R.A.J. Lester, Gang Tong, CE Jahr
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Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen +10 more
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