Results 191 to 200 of about 1,350,887 (263)

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

NMDA receptor-dependent structural plasticity links early life stress to persistent aggression. [PDF]

Neurobiol Stress
Jacobs JT, Nordman JC.
europepmc   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

Pairing ampakine with brief hypoxia evokes phrenic neuroplasticity via a spinal NMDA receptor-mediated mechanism. [PDF]

Function (Oxf)
Thakre PP, Rana S, Perim RR, Mitchell GS, Fuller DD.   +4 more
europepmc   +1 more source

Noise‐induced reduction and early recovery of superior paraolivary nucleus sound‐offset responses

The Journal of Physiology, EarlyView.
Abstract figure legend Acoustic over‐exposure transiently disrupts auditory temporal processing in mouse superior paraolivary nucleus neurons. In control conditions, neurons exhibit robust sound‐offset (OFF) responses, which are abolished immediately following noise trauma, indicating impaired temporal encoding.
Mihai Stancu, Ezhilarasan Rajaram, Joseph A. Kroeger, Benedikt Grothe, Conny Kopp‐Scheinpflug   +4 more
wiley   +1 more source

Anti-NMDA Receptor Encephalitis with Predominant Psychiatric Symptomatology and Diagnostic Dilemmas: A Case Report. [PDF]

Reports (MDPI)
Siladji D, Ljubotin L, Amidzic J, Kuljancic D, Stankovic Stevanovic N.   +4 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Incomplete T-cell tolerance and epitope-specific responses to the NR1 subunit in NMDA receptor antibody-associated encephalitis. [PDF]

Brain Commun
Brown RL, Albuquerque A, Thomas S, Holler A, Angus-Leppan H, Sette A, Lindestam Arlehamn C, Hart M, Zandi MS, Vincent A, Stauss HJ, Lunn MP, Morris EC.   +12 more
europepmc   +1 more source

Dextromethorphan Hydrobromide‐Bupropion Hydrochloride for Agitation in Dementia: Combination or Two Stand‐Alone Drugs

Journal of the American Geriatrics Society, EarlyView.
Eric E. Brown, Todd Semla, David B. Reuben   +2 more
wiley   +1 more source