Results 321 to 330 of about 186,082 (377)
Disrupted callosal connectivity underlies long-lasting sensory-motor deficits in an NMDA receptor antibody encephalitis mouse model. [PDF]
J Clin InvestZhou J +21 more
europepmc +1 more source
Racial and Ethnic Disparities in the Incidence of Anti-NMDA Receptor Encephalitis. [PDF]
Neurol Neuroimmunol NeuroinflammAlsalek S +6 more
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NMDA receptor activation drives early synapse formationin vivo
Leibold NS +5 more
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The Neuroscientist, 2007
The amino acid L-Glutamate acts as the most ubiquitous mediator of excitatory synaptic transmission in the central nervous system. Glutamatergic transmission is central for diverse brain functions, being particularly important for learning, memory, and cognition. In brain pathology, excessive release of glutamate triggers excitotoxic neural cell death
Verkhratsky, Alexei, Kirchhoff, Frank
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The amino acid L-Glutamate acts as the most ubiquitous mediator of excitatory synaptic transmission in the central nervous system. Glutamatergic transmission is central for diverse brain functions, being particularly important for learning, memory, and cognition. In brain pathology, excessive release of glutamate triggers excitotoxic neural cell death
Verkhratsky, Alexei, Kirchhoff, Frank
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Alcohol, 1990
The actions of glutamate, the major excitatory amino acid in the CNS, are mediated by three receptor subtypes: kainate, quisqualate and N-methyl-D-aspartate (NMDA) receptors. Ethanol, in vitro, is a potent and selective inhibitor of the actions of agonists at the NMDA receptor.
Kathleen A. Grant +5 more
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The actions of glutamate, the major excitatory amino acid in the CNS, are mediated by three receptor subtypes: kainate, quisqualate and N-methyl-D-aspartate (NMDA) receptors. Ethanol, in vitro, is a potent and selective inhibitor of the actions of agonists at the NMDA receptor.
Kathleen A. Grant +5 more
openaire +3 more sources
Mechanisms of NMDA receptor regulation
Current Opinion in Neurobiology, 2023N-methyl-D-aspartate receptors (NMDARs) are glutamate-gated ion channels widely expressed in the central nervous system that play key role in brain development and plasticity. On the downside, NMDAR dysfunction, be it hyperactivity or hypofunction, is harmful to neuronal function and has emerged as a common theme in various neuropsychiatric disorders ...
Mony, Laetitia, Paoletti, Pierre
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Current Opinion in Neurobiology, 2004
Dynamic modulation of the number of postsynaptic glutamate receptors is considered one of the main mechanisms for altering the strength of excitatory synapses in the central nervous system (CNS). However, until recently N-methyl-d-aspartate (NMDA) receptors were considered relatively stable once in the plasma membrane, especially in comparison with ...
Yue-Qiao Huang +2 more
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Dynamic modulation of the number of postsynaptic glutamate receptors is considered one of the main mechanisms for altering the strength of excitatory synapses in the central nervous system (CNS). However, until recently N-methyl-d-aspartate (NMDA) receptors were considered relatively stable once in the plasma membrane, especially in comparison with ...
Yue-Qiao Huang +2 more
openaire +3 more sources
Synapse, 1991
AbstractIdentified crayfish visual interneurons respond to illumination with a compound EPSP of up to 40 mV. L‐gultamate, quisqualate, and kainate mimic the depolarizing action of the natural transmitter. In reduced Mg2+, N‐methyl‐D‐aspartate (NMDA) elicits a depolarization with a reversal potential (Erev) = −60 mV. Erev is independent of extracellular
Cindy Pfeiffer-Linn, Raymon M. Glantz
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AbstractIdentified crayfish visual interneurons respond to illumination with a compound EPSP of up to 40 mV. L‐gultamate, quisqualate, and kainate mimic the depolarizing action of the natural transmitter. In reduced Mg2+, N‐methyl‐D‐aspartate (NMDA) elicits a depolarization with a reversal potential (Erev) = −60 mV. Erev is independent of extracellular
Cindy Pfeiffer-Linn, Raymon M. Glantz
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NMDA receptors and schizophrenia
Current Opinion in Pharmacology, 2007The pathophysiology of schizophrenia is poorly understood but is likely to involve alterations in excitatory glutamatergic signaling molecules in several areas of the brain. Clinical and experimental evidence has shown that expression of the N-methyl-D-aspartate (NMDA) receptor and intracellular NMDA receptor-interacting proteins of the glutaminergic ...
James H. Meador-Woodruff +3 more
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