Results 11 to 20 of about 4,332,931 (306)

Searching for the Best Values of NMR Shielding and Spin-Spin Coupling Parameters: CH_4-nF_n Series of Molecules as the Example

Molecules, 2023
Attempts at the theoretical interpretation of NMR spectra have a very long and fascinating history. Present quantum chemical calculations of shielding and indirect spin-spin couplings permit modeling NMR spectra when small, isolated molecules are studied.
Karol Jackowski, Mateusz A. Słowiński
doaj   +1 more source

Mapping the electrostatic potential of the nucleosome acidic patch [PDF]

, 2021
The nucleosome surface contains an area with negative electrostatic potential known as the acidic patch, which functions as a binding platform for various proteins to regulate chromatin biology.
Zhang, Heyi, Schellevis, Raymond, Horn, Velten, van Ingen, Hugo, Eerland, Jelmer, NMR Spectroscopy, Sub NMR Spectroscopy   +6 more
core  

Revising the mechanism of p75NTR activation: intrinsically monomeric state of death domains invokes the "helper" hypothesis

Scientific Reports, 2020
The neurotrophin receptor p75NTR plays crucial roles in neuron development and regulates important neuronal processes like degeneration, apoptosis and cell survival. At the same time the detailed mechanism of signal transduction is unclear.
Sergey A. Goncharuk, Lilya E. Artemieva, Kirill D. Nadezhdin, Alexander S. Arseniev, Konstantin S. Mineev   +4 more
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Secondary structure determination of conserved SARS-CoV-2 RNA elements by NMR spectroscopy

Nucleic Acids Research, 2020
The current pandemic situation caused by the Betacoronavirus SARS-CoV-2 (SCoV2) highlights the need for coordinated research to combat COVID-19. A particularly important aspect is the development of medication.
A. Wacker, J. Weigand, Sabine R. Akabayov, N. Altincekic, J. Bains, Elnaz Banijamali, O. Binas, J. Castillo-Martínez, E. Çetiner, B. Ceylan, Liang-Yuan Chiu, Jesse Davila-Calderon, K. Dhamotharan, E. Duchardt-Ferner, J. Ferner, L. Frydman, B. Fürtig, J. Gallego, J. T. Grün, C. Hacker, Christina Haddad, Martin J. Hähnke, M. Hengesbach, F. Hiller, Katharina F. Hohmann, Daniel Hymon, V. de Jesus, H. Jonker, H. Keller, Božana Knezic, Tom Landgraf, F. Löhr, Le Luo, K. Mertinkus, C. Muhs, Mihajlo Novakovic, Andreas Oxenfarth, Martina Palomino-Schätzlein, Katja Petzold, S. A. Peter, D. Pyper, N. Qureshi, Magdalena Riad, C. Richter, K. Saxena, Tatjana Schamber, T. Scherf, Judith Schlagnitweit, A. Schlundt, Robbin Schnieders, H. Schwalbe, Alvaro Simba-Lahuasi, S. Sreeramulu, E. Stirnal, Alexey Sudakov, Jan-Niklas Tants, B. Tolbert, Jennifer Vögele, Lena Weiß, J. Wirmer-Bartoschek, M. A. Wirtz Martin, J. Wöhnert, Heidi Zetzsche   +62 more
semanticscholar   +1 more source

Structural characterization of intrinsically disordered proteins by NMR spectroscopy. [PDF]

, 2013
Recent advances in NMR methodology and techniques allow the structural investigation of biomolecules of increasing size with atomic resolution. NMR spectroscopy is especially well-suited for the study of intrinsically disordered proteins (IDPs) and ...
Contreras-Martos, Sara, Peter Tompa, Cedeno, Cesyen, Simone Kosol, Kosol, Simone, Tompa, Péter, Sara Contreras-Martos, Cesyen Cedeño   +7 more
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Enantiotropy of Simvastatin as a Result of Weakened Interactions in the Crystal Lattice: Entropy-Driven Double Transitions and the Transient Modulated Phase as Seen by Solid-State NMR Spectroscopy

Molecules, 2022
In crystalline molecular solids, in the absence of strong intermolecular interactions, entropy-driven processes play a key role in the formation of dynamically modulated transient phases.
Jiri Brus, Jiri Czernek, Martina Urbanova, Ctirad Červinka   +3 more
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Protein folding on the ribosome studied using NMR spectroscopy [PDF]

, 2013
NMR spectroscopy is a powerful tool for the investigation of protein folding and misfolding, providing a characterization of molecular structure, dynamics and exchange processes, across a very wide range of timescales and with near atomic resolution.
Christodoulou, J, Christodoulou, John, Launay, H, Cabrita, L.D., Launay, H., Waudby, CA, Cabrita, LD, Waudby, Christopher A.   +7 more
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Energetics of Excitatory and Inhibitory Neurotransmission in Aluminum Chloride Model of Alzheimer’s Disease: Reversal of Behavioral and Metabolic Deficits by Rasa Sindoor

Frontiers in Molecular Neuroscience, 2017
Alzheimer’s disease (AD) is an age-related neurodegenerative disorder, characterized by progressive loss of cognitive functions and memory. Excessive intake of aluminum chloride in drinking water is associated with amyloid plaques and neurofibrillary ...
Kamal Saba, Niharika Rajnala, Pandichelvam Veeraiah, Vivek Tiwari, Rohit K. Rana, Subhash C. Lakhotia, Anant B. Patel   +6 more
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Formation of the β-barrel assembly machinery complex in lipid bilayers as seen by solid-state NMR

Nature Communications, 2018
The β-barrel assembly machinery (BAM) catalyzes β-barrel protein insertion into the outer membrane of E.coli. Here authors employ high-sensitivity solid-state NMR to reveal how the lipid environment and formation of the BamA-BamCDE complex affect BamA ...
Cecilia Pinto, Deni Mance, Tessa Sinnige, Mark Daniëls, Markus Weingarth, Marc Baldus   +5 more
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Regulation of the Target of Rapamycin and Other Phosphatidylinositol 3-Kinase-Related Kinases by Membrane Targeting

Membranes, 2015
Phosphatidylinositol 3-kinase-related kinases (PIKKs) play vital roles in the regulation of cell growth, proliferation, survival, and consequently metabolism, as well as in the cellular response to stresses such as ionizing radiation or redox changes. In
Maristella De Cicco, Munirah S. Abd Rahim, Sonja A. Dames   +2 more
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