Results 1 to 10 of about 190,531 (261)
Ultrahigh‐Resolution NMR Spectroscopy [PDF]
Angewandte Chemie - International Edition, 2014 All psyched up: A flexible and general pure shift experiment (PSYCHE) has been developed that offers superior sensitivity, spectral purity, and tolerance of strong coupling over existing methods for broadband homonuclear decoupling. The partial spectra of estradiol in [D6]DMSO obtained by normal 1H NMR spectroscopy and PSYCHE are shown for comparison.
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Hyperdimensional NMR Spectroscopy [PDF]
Journal of the American Chemical Society, 2006 Hyperdimensional NMR describes the multiple interactions between a large number, N, of coupled nuclear spins. We show how to construct a hypothetical N-dimensional spectrum from a limited set of low-dimensional measurements, exploiting the concept of projection-reconstruction.
Eriks, Kupce, Ray, Freeman
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In-Cell NMR Spectroscopy [PDF]
ChemBioChem, 2005 The role of a protein inside a cell is determined by both its location and its conformational state. Although fluorescence techniques are widely used to determine the cellular localization of proteins in vivo, these approaches cannot provide detailed information about a protein's three-dimensional state.
Zach, Serber +3 more
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Nuclear Dipole Moments and Shielding Constants of Light Nuclei Measured in Magnetic Fields
Magnetochemistry, 2023 Nuclear magnetic resonance (NMR) is a branch of spectroscopy commonly used for identifying the chemical structure of various materials. One of the areas in which NMR provides accurate data is the determination of nuclear magnetic moments.
Włodzimierz Makulski +2 more
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Glutamate and GABA Homeostasis and Neurometabolism in Major Depressive Disorder
Frontiers in Psychiatry, 2021 Major depressive disorder (MDD) is a leading cause of distress, disability, and suicides. As per the latest WHO report, MDD affects more than 260 million people worldwide.
Ajay Sarawagi +4 more
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Characterization of a fold in TANGO1 evolved from SH3 domains for the export of bulky cargos
Nature Communications, 2023 Bulky cargos like procollagens, apolipoproteins, and mucins exceed the size of conventional COPII vesicles. During evolution a process emerged in metazoans, predominantly governed by the TANGO1 protein family, that organizes cargo at the exit sites of ...
Oliver Arnolds, Raphael Stoll
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Molecules, 2023 Attempts at the theoretical interpretation of NMR spectra have a very long and fascinating history. Present quantum chemical calculations of shielding and indirect spin-spin couplings permit modeling NMR spectra when small, isolated molecules are studied.
Karol Jackowski, Mateusz A. Słowiński
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In-cell NMR spectroscopy [PDF]
Progress in Nuclear Magnetic Resonance Spectroscopy, 2011 Interactions between biological macromolecules give rise to and regulate biological activity. This activity is manifest through structural dynamics and changes in the macromolecular structures that comprise these interactions [1-3]. Until recently, mostly in vitro techniques have been used to study macromolecular interactions that govern biological ...
Andres Y, Maldonado +2 more
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Diffusion NMR spectroscopy [PDF]
NMR in Biomedicine, 2001 AbstractMR offers unique tools for measuring molecular diffusion. This review focuses on the use of diffusion‐weighted MR spectroscopy (DW‐MRS) to non‐invasively quantitate the translational displacement of endogenous metabolites in intact mammalian tissues.
Nicolay, K. +4 more
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Scientific Reports, 2020 The neurotrophin receptor p75NTR plays crucial roles in neuron development and regulates important neuronal processes like degeneration, apoptosis and cell survival. At the same time the detailed mechanism of signal transduction is unclear.
Sergey A. Goncharuk +4 more
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