Results 21 to 30 of about 4,332,931 (306)

A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V

open access: yesNature Communications, 2022
Constriction of the selectivity filter is assumed to be a hallmark of C-type inactivation in K+ channels. Using different high-resolution methods, this study shows a distinct C-type inactivation mechanism in a KcsA mutant that emulates Kv-channels.
Ahmed Rohaim   +8 more
doaj   +1 more source

Low-field benchtop NMR spectroscopy: status and prospects in natural product analysis.

open access: yesPhytochemical Analysis, 2020
INTRODUCTION Since a couple of years, low-field (LF) nuclear magnetic resonance (NMR) spectrometers (40-100 MHz) have re-entered the market. They are used for various purposes including analyses of natural products. Similar to high-field instruments (300-
T. van Beek
semanticscholar   +1 more source

High-resolution solid state NMR experiments for the characterization of calcium phosphate biomaterials and biominerals [PDF]

open access: yes, 2011
Calcium phosphates form a vast family of biominerals, which have attracted much attention in fields like biology, medicine, and materials science, to name a few.
Hanna, John   +55 more
core   +5 more sources

Exploiting periodic first-principles calculations in NMR spectroscopy of disordered solids [PDF]

open access: yes, 2013
Much of the information contained within solid-state nuclear magnetic resonance (NMR) spectra remains unexploited because of the challenges in obtaining high-resolution spectra and the difficulty in assigning those spectra.
Ashbrook, Sharon Elizabeth   +3 more
core   +1 more source

Quantum diamond spectrometer for nanoscale NMR and ESR spectroscopy [PDF]

open access: yesNature Protocols, 2019
Nitrogen-vacancy (NV) quantum defects in diamond are sensitive detectors of magnetic fields. Owing to their atomic size and optical readout capability, they have been used for magnetic resonance spectroscopy of nanoscale samples on diamond surfaces. Here,
D. Bucher   +6 more
semanticscholar   +1 more source

Atomic-level insight into mRNA processing bodies by combining solid and solution-state NMR spectroscopy

open access: yesNature Communications, 2019
Processing bodies are membrane less organelles that contain enzymes involved in mRNA turnover, among them enhancer of decapping 3 (Edc3). Here the authors use solid- and solution-state NMR spectroscopy to characterize the structural organization and ...
Reinier Damman   +5 more
doaj   +1 more source

Solid-state NMR spectroscopy in pharmaceutical sciences

open access: yes, 2020
Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials in a non-disruptive and non-invasive manner. The obtained molecular properties at macroscopic and microscopic scales offer critical knowledge on the physiochemical ...
Mingyue Li, Wei Xu, Yongchao Su
semanticscholar   +1 more source

Methyl TROSY spectroscopy: A versatile NMR approach to study challenging biological systems.

open access: yesProgress in nuclear magnetic resonance spectroscopy, 2020
A major goal in structural biology is to unravel how molecular machines function in detail. To that end, solution-state NMR spectroscopy is ideally suited as it is able to study biological assemblies in a near natural environment.
S. Schütz, R. Sprangers
semanticscholar   +1 more source

Characterization of the cell wall of a mushroom forming fungus at atomic resolution using solid-state NMR spectroscopy

open access: yesThe Cell Surface, 2020
Cell walls are essential in the interaction of fungi with the (a)biotic environment and are also key to hyphal morphogenesis and mechanical strength. Here, we used solid-state NMR (ssNMR) spectroscopy combined with HPLC and GC–MS to study the structural ...
Helena Leona Ehren   +5 more
doaj   +1 more source

Combining NMR spectroscopy and organic synthesis : from small building blocks to large biomolecules [PDF]

open access: yes, 2014
Detailed knowledge of the structure of bio molecules with atomic resolution is essential for the understanding of their function. Moreover the identification and quantification of their dynamic processes are important, as they are the origin of molecular
Gsellinger, Heiko
core   +1 more source

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